Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1258105 | Chinese Chemical Letters | 2010 | 4 Pages |
Abstract
Fatty acid modified glucagon-like peptide-1 (7-36) amide was synthesized efficiently on Rink-Amide-MBHA resin by microwave-assisted solid phase method. The method of thermal and controlled microwave irradiation provided impressive enhancements in product yield, selectivity, and reaction rate. The coupling time was dramatically decreased to 6 min, and the desired products were obtained in high yield and purity.
Related Topics
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Chemistry
Chemistry (General)
Authors
Shuai Jian Ni, Hui Bin Zhang, Wen Long Huang, Jin Pei Zhou, Hai Qian,