| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1258421 | Chinese Chemical Letters | 2008 | 5 Pages |
Abstract
A series of novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine were synthesized and structurally characterized by 1H NMR and MS. Their in vivo anti-platelet aggregation activities were evaluated. A 3D-QSAR was performed using the CoMFA and the CoMSIA. This model provided useful guidelines for novel anti-platelet thienopyridines design.
Keywords
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Physical Sciences and Engineering
Chemistry
Chemistry (General)
![Synthesis, activity evaluation and 3D-QSAR study of some novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine](/preview/png/1258421.png "First Page Preview: Synthesis, activity evaluation and 3D-QSAR study of some novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine")
Authors
Die Cheng, Deng Ke Liu, Mo Liu, Ying Liu, Wei Ren Xu, Chang Xiao Liu,