Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1258445 | Chinese Chemical Letters | 2008 | 4 Pages |
Abstract
Two series of novel derivatives of imidazo[4,5-b]pyridine were synthesized. These compounds could be used as side chains of semisynthesised ketolide antibiotics. The side chains have free amine group which can attached to ketolide core. Macrolides with this kind of side chains will show obvious activities against erythromycin-resistant strains. The structure of the side chains was confirmed by 1H, 13C NMR, MS, HMBC spectra.
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Authors
Lu Liu, Peng Xu, Liang Zhou, Ping Sheng Lei,