| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1258450 | Chinese Chemical Letters | 2008 | 4 Pages |
Abstract
Tetracycline analogs were designed and synthesized and their bone affinities were tested on hydroxyapatite. The results showed that the carbonyl-amide-enol structure in A ring and phenol–ketone structure in BCD ring may be responsible for tetracycline's high bone affinity and either A ring or BCD ring has a planar conformation is essential.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Wen Cai Huang, Hu Zheng, Ling Ling Weng,