Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1258702 | Chinese Chemical Letters | 2007 | 4 Pages |
Abstract
To enable insulin as multi-drug carrier, we designed and synthesized dendritic linker molecule bearing three 5-fluorouracil residues at the branch ends. The new conjugate showed excellent water solubility. The stabilities under different conditions were investigated. The results showed that the conjugate was a potential prodrug to release free 5-Fu.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Juan Huang, Jian Wei Wang, Tao Gong, Zhi Rong Zhang,