| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1364796 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
The synthesis of mono- and bisphosphorothioate analogues of 3′,5′-cyclic diguanylic acid (cdiGMP) via the modified H-phosphonate chemistry is reported. The immunostimulatory properties of these analogues were compared with those of cdiGMP.
Graphical abstractThe phosphorothioate analogues of cdiGMP were synthesized and their immunostimulatory properties were compared.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hongbin Yan, Xiaolu Wang, Rhonda KuoLee, Wangxue Chen,