| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1373109 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
Herein we describe the design and synthesis of a novel series of potent thienopyrimidine P2Y12 inhibitors and the negative impact protein binding has on the inhibition of platelet aggregation.
Graphical abstractHerein we describe the design and synthesis of a novel series of potent thienopyrimidine P2Y12 inhibitors and the negative impact protein binding has on the inhibition of platelet aggregation.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Steven W. Kortum, Rhonda M. Lachance, Barbara A. Schweitzer, Gopichand Yalamanchili, Hayat Rahman, Michael D. Ennis, Rita M. Huff, Ruth E. TenBrink,