Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2093985 | Stem Cell Research | 2016 | 5 Pages |
Abstract
The human embryonic stem cell line RCe009-A (RC-5) was derived from a frozen and thawed Day 2 embryo voluntarily donated as unsuitable and surplus to requirement for fertility treatment following informed consent under licence from the UK Human Fertilisation and Embryology Authority. RCe009-A carries the common DF508 mutation on the cystic fibrosis trans-membrane regulator gene associated with the disease cystic fibrosis. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available.
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Authors
P.A. De Sousa, B. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, J. Gardner, J.M. Downie, M. Bateman, A. Courtney,