Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2432651 | Fish & Shellfish Immunology | 2010 | 6 Pages |
Abstract
Immunogenicity of different antigen preparations of outer membrane proteins (OMP) of Aeromonas hydrophila such as Poly d, l-lactide-co-glycolic acid (PLGA) microparticles, oil emulsion, neat OMP and bacterial whole cells were compared through intra-peritoneal injection in fish, Labeo rohita. Among these preparations, PLGA encapsulated antigen stimulated both innate and adaptive immune parameters and the immunogenicity exhibited by PLGA microparticles was significantly higher (p < 0.05) at both 21 and 42 days post-immunization suggesting that the above delivery system would be a novel antigen carrier for parenteral immunization in fish, Labeo rohita
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Authors
T. Behera, P.K. Nanda, C. Mohanty, D. Mohapatra, P. Swain, B.K. Das, P. Routray, B.K. Mishra, S.K. Sahoo,