Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5143019 | Chinese Chemical Letters | 2017 | 5 Pages |
Abstract
To recognize the antineoplastic target(s) of DMAKO-05 and its analogs, four biotinylated DMAKO derivatives were designed and prepared. The biotin moiety was successfully introduced in the molecule through a modified Mitsunobu reaction, which conserved moderate to excellent anticancer activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Guang Huang, Qing-Qing Meng, Wen Zhou, Qi-Jing Zhang, Jin-Yun Dong, Shao-Shun Li,