Article ID Journal Published Year Pages File Type
5143212 Chinese Chemical Letters 2016 4 Pages PDF
Abstract
A series of chiral N-allyl-N-benzylamides that contain a 2H-chromen-2-one moiety were designed for the synthesis of benzo[f]isoindol-1-ones via an intramolecular Diels-Alder and a subsequent retro-Diels-Alder reaction with the expulsion of CO2. Both the yield (80%-89%) and absolute stereocontrol of the tandem reaction were high when an electron-withdrawing group was attached to the dienophile.
Related Topics
Physical Sciences and Engineering Chemistry Chemistry (General)
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