Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5143212 | Chinese Chemical Letters | 2016 | 4 Pages |
Abstract
A series of chiral N-allyl-N-benzylamides that contain a 2H-chromen-2-one moiety were designed for the synthesis of benzo[f]isoindol-1-ones via an intramolecular Diels-Alder and a subsequent retro-Diels-Alder reaction with the expulsion of CO2. Both the yield (80%-89%) and absolute stereocontrol of the tandem reaction were high when an electron-withdrawing group was attached to the dienophile.
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Authors
Jian Zhang, Jin-Long Wu,