Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7693134 | Chinese Chemical Letters | 2018 | 12 Pages |
Abstract
A glucosidic indole-lignan conjugate with a novel carbon skeleton, named isatindolignanoside A (1), was isolated from an aqueous extract of the Isatis indigotica roots “ban lan gen”. Its structure was determined by comprehensive analysis of spectroscopic data, enzyme hydrolysis, and electronic CD calculations. Compound 1 is active against Coxsackie virus B3 and represents the first example of natural product having a structural feature of conjugation between indole and lignan, and its plausible biosynthetic pathway is postulated.
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Physical Sciences and Engineering
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Authors
Lingjie Meng, Qinglan Guo, Minghua Chen, Jiandong Jiang, Yuhuan Li, Jiangong Shi,