| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7693267 | Chinese Chemical Letters | 2018 | 6 Pages |
Abstract
Linaclotide and its d-enantiomer were obtained through Fmoc solid phase peptide synthesis method and co-crystalized through racemic crystallization. The crystal structure showed that linaclotide has a tight, three-beta turns structure immobilized by three pairs of disulfide bonds.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Chenchen Chen, Shuai Gao, Qian Qu, Pengcheng Mi, Anjin Tao, Yi-Ming Li,