Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7693288 | Chinese Chemical Letters | 2018 | 4 Pages |
Abstract
We further emphasized the key roles of the A342xxxG346xxG349xxxT353xxL356xxxV360 motif in the left-handed configuration and the L345xxxG349xxG352xxxL356 motif in the right-handed configuration. In addition, we revealed that the juxtamembrane (JM) domain within A375 could determine the RAGE TM dimeric structure. Overall, we provide the molecular insights into the switching dimerization of RAGE TM domains, as well as the regulation from the JM domains mediated by the anionic lipids.
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Authors
Jialin Chen, Fude Sun, Peng Chen, Mengya Chai, Lida Xu, Shi-Zhong Luo,