Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7693299 | Chinese Chemical Letters | 2018 | 6 Pages |
Abstract
A potent peptide inhibitor of estrogen receptor α (ER-α) with significantly increased cellular uptake and cellular distribution was developed by cell penetrating peptide attachment. The resulted peptide conjugate showed selective toxicity towards estrogen receptor positive cell lines and induced decreased transcription of estrogen receptor α downstream genes.
Related Topics
Physical Sciences and Engineering
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Chemistry (General)
Authors
Xuan Qin, Hui Zhao, Yanhong Jiang, Feng Yin, Yuan Tian, Mingsheng Xie, Xiyang Ye, Naihan Xu, Zigang Li,