Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7693376 | Chinese Chemical Letters | 2018 | 11 Pages |
Abstract
Low molecular weight heparins (LMWHs) are the most widely used anticoagulant drugs produced by chemical or enzymatic modification of parent heparin polysaccharides. The present article reviews recent advances in orthogonal and complementary mass spectrometry (MS) methodologies towards complete elucidation of natural and modified structures in LMWHs that possibly affect the drug quality, safety and efficacy.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Zhangjie Wang, Lianli Chi,