Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8483777 | Journal of Exotic Pet Medicine | 2018 | 13 Pages |
Abstract
The objective of this preliminary study was to establish a reference range for plasma fructosamine concentration and fructosamine-albumin ratio in healthy ferrets and to compare these reference intervals to values obtained from hypoglycemic ferrets. Fructosamine concentration has been shown to reflect blood glucose concentration over the previous 1 to 2 weeks in other animal species, and may be a useful indicator of chronic hypoglycemia in ferrets diagnosed with insulinoma. Plasma fructosamine was measured with an automated colorimetric assay using nitroblue tetrazolium. Thirty-two clinically healthy and 5 hypoglycemic ferrets were included in the study. The reference interval in healthy ferrets for fructosamine was 110 (98 to 123) - 203 (191 to 218) μmol/L, and the reference interval for plasma fructosamine-albumin ratio was 5.1 (4.6 to 5.6) - 8.6 (8.2 to 9.0) μmol/g. Results for hypoglycemic ferrets were within the ranges for both fructosamine and fructosamine-albumin ratio. As there were no significant differences between the healthy and hypoglycemic ferrets, this study suggests that fructosamine concentration and fructosamine-albumin ratio are not likely to be useful in determining insulinoma-associated chronic hypoglycemia in ferrets.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Animal Science and Zoology
Authors
Alexis DVM, IPSAV (Zoological Medicine), Frederic DVM, Elodie MSc, Sylvain DVM, MSc, DES (Zoological Medicine), Dip. ACZM,