Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8483823 | Journal of Exotic Pet Medicine | 2018 | 18 Pages |
Abstract
A 2-year-old pet budgerigar was presented after a period of general malaise that was unresponsive to supportive therapy. Radiographic images revealed a marked hepatomegaly. Hematology results indicated the bird had a severe leukocytosis with marked discrepancy between the hemocytometer white blood cell (WBC) count and WBC estimated from the smear. The leukocytosis was characterized by an extreme heterophilia with marked left shift, including the presence of metamyelocytes and promyelocytes with marked toxic changes, and a marked monocytosis, consistent with a leukemoid response. The bird died despite supportive treatment. Hepatosplenomegaly was present at necropsy. Histopathology of multiple tissues demonstrated acid-fast organisms on Ziehl-Neelsen staining, subsequently identified as Mycobacterium genavese by polymerase chain reaction analysis. Mycobacteriosis should be considered as a differential diagnosis in the presence of a severe leukemoid response with multiple heterophilic precursors in avian species.
Keywords
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Animal Science and Zoology
Authors
Michelle BVM&S, MANZCVS (Avian Health), CertAVP (ZooMed) MRCVS, Natalie BVSc, MVS, MANZCVS (SA Medicine, Pathology), GCUT, Dip. ACVP (Clinical Pathology), Philip BVSc, MANZCVS (Avian Health), Patricia BVSc, PhD, FANZCVS (Avian),