Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor Fulltext Access 10 Pages 2005
Reduced regional cerebral blood flow in SPG4-linked hereditary spastic paraplegia Fulltext Access 10 Pages 2005
Neuroimaging as a marker of the onset and progression of Alzheimer's disease Fulltext Access 10 Pages 2005
Lipid peroxidation during ischemia depends on ischemia time in warm ischemia and reperfusion of rat liver Fulltext Access 10 Pages 2005
CD36 overexpression in ritonavir-treated THP-1 cells is reversed by α-tocopherol Fulltext Access 10 Pages 2005
Nitric oxide-related species-induced protein oxidation: Reversible, irreversible, and protective effects on enzyme function of papain Fulltext Access 10 Pages 2005
Sensitivity and specificity of electrodiagnostic criteria for CIDP using ROC curves: comparison to patients with diabetic and MGUS associated neuropathies Fulltext Access 10 Pages 2005
Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease Fulltext Access 10 Pages 2005
Thiopurine methyltransferase (TPMT) heterozygosity and enzyme activity as predictive tests for the development of azathioprine-related adverse events Fulltext Access 10 Pages 2005
Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study Fulltext Access 10 Pages 2005
Treatment adherence in the Estonian postmenopausal hormone therapy (EPHT) trial [ISRCTN35338757] Fulltext Access 10 Pages 2005
Estimated numbers of postmenopausal women treated by hormone therapy in France Fulltext Access 10 Pages 2005
Prevalence and correlates of hormonal therapy among Israeli women in the post-WHI era Fulltext Access 10 Pages 2005
Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced downregulation of Akt Fulltext Access 11 Pages 2005
Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats Fulltext Access 11 Pages 2005
Synergism of Helicobacter pylori infection and stress on the augmentation of gastric mucosal damage and its prevention with α-tocopherol Fulltext Access 11 Pages 2005
Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox Fulltext Access 11 Pages 2005
Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Fulltext Access 11 Pages 2005
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFκB activation in vivo Fulltext Access 11 Pages 2005
Characterization of Nrf2 activation and heme oxygenase-1 expression in NIH3T3 cells exposed to aqueous extracts of cigarette smoke Fulltext Access 11 Pages 2005
Central role of PKCδ in glycoxidation-dependent apoptosis of human neurons Fulltext Access 11 Pages 2005
Mitochondrial permeability transition as a source of superoxide anion induced by the nitroaromatic drug nimesulide in vitro Fulltext Access 11 Pages 2005
Mechanistic similarities between oxidation of hydroethidine by Fremy's salt and superoxide: Stopped-flow optical and EPR studies Fulltext Access 11 Pages 2005
Identification of an E-box motif as a transcriptional repressor element in the proximal promoter region of the GCLC gene in rat lung epithelial L2 cells Fulltext Access 11 Pages 2005
Modification of endoplasmic reticulum Ca2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease Fulltext Access 11 Pages 2005
Exogenous superoxide mediates pro-oxidative, proinflammatory, and procoagulatory changes in primary endothelial cell cultures Fulltext Access 11 Pages 2005
Mitochondrial redox state regulates transcription of the nuclear-encoded mitochondrial protein manganese superoxide dismutase: a proposed adaptive response to mitochondrial redox imbalance Fulltext Access 11 Pages 2005
Redox properties of the lipocalin α1-microglobulin: Reduction of cytochrome c, hemoglobin, and free iron Fulltext Access 11 Pages 2005
Neurotoxicity of nitroxyl: Insights into HNO and NO biochemical imbalance Fulltext Access 11 Pages 2005
Macrophage uptake and recycling of ascorbic acid: Response to activation by lipopolysaccharide Fulltext Access 11 Pages 2005
Drosophila simulans as a novel model for studying mitochondrial metabolism and aging Fulltext Access 11 Pages 2005
Visual event-related potentials under different interstimulus intervals in Parkinson's disease: Relation to motor disability, WAIS-R, and regional cerebral blood flow Fulltext Access 11 Pages 2005
Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women Fulltext Access 11 Pages 2005
Construction of two instruments for the presumptive detection of post-menopausal women with low spinal bone mass by means of clinical risk factors Fulltext Access 11 Pages 2005
Patient-reported impact of urinary incontinence-Results from treatment seeking women in 14 European countries Fulltext Access 11 Pages 2005
Characteristics of female outpatients with urinary incontinence participating in a 6-month observational study in 14 European countries Fulltext Access 11 Pages 2005
Trends in middle-aged women's reports of symptoms, use of hormone therapy and attitudes towards it Fulltext Access 11 Pages 2005
Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite Fulltext Access 11 Pages 2005
Hidden function of neuronal nicotinic acetylcholine receptor β2 subunits in ganglionic transmission: comparison to α5 and β4 subunits Fulltext Access 11 Pages 2005
Nitric oxide-induced resistance to hydrogen peroxide stress is a glutamate cysteine ligase activity-dependent process Fulltext Access 11 Pages 2005
Glutathione depletion inhibits lipopolysaccharide-induced intercellular adhesion molecule 1 synthesis Fulltext Access 11 Pages 2005
Tyrosine phosphorylation in mitochondria: A new frontier in mitochondrial signaling Fulltext Access 11 Pages 2005
Effects of vitamin restriction and supplementation on rat intestinal epithelial cell apoptosis Fulltext Access 11 Pages 2005
Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide-A role for GFRP? Fulltext Access 11 Pages 2005
A novel protocol to identify and quantify all spin trapped free radicals from in vitro/in vivo interaction of HO and DMSO: LC/ESR, LC/MS, and dual spin trapping combinations Fulltext Access 11 Pages 2005
4-Hydroxynonenal modulation of p53 family gene expression in the SK-N-BE neuroblastoma cell line Fulltext Access 11 Pages 2005
Gene expression profiling of pulpal tissue reveals the molecular complexity of dental caries Fulltext Access 11 Pages 2005
Aberrant accentuation of neurofibrillary degeneration in the hippocampus of Alzheimer's disease with amyloid precursor protein 717 and presenilin-1 gene mutations Fulltext Access 11 Pages 2005
Predictors of mortality: an international comparison of socio-demographic and health characteristics from six longitudinal studies on aging: the CLESA project Fulltext Access 11 Pages 2005
Lifelong heterogeneity in fecundity is insufficient to explain late-life fecundity plateaus in Drosophila melanogaster Fulltext Access 11 Pages 2005
Human aging alters the first phase of the molecular response to stress in T-cells Fulltext Access 11 Pages 2005
Stability of RNA isolated from human trabecular bone at post-mortem and surgery Fulltext Access 11 Pages 2005
Identification of Li+ binding sites and the effect of Li+ treatment on phospholipid composition in human neuroblastoma cells: a 7Li and 31P NMR study Fulltext Access 11 Pages 2005
The healing rabbit medial collateral ligament of the knee responds to systemically administered glucocorticoids differently than the uninjured tissues of the same joint or the uninjured MCL: A paradoxical shift in impact on specific mRNA levels and MMP-13 Fulltext Access 11 Pages 2005
Intrahippocampal administration of the branched-chain α-hydroxy acids accumulating in maple syrup urine disease compromises rat performance in aversive and non-aversive behavioral tasks Fulltext Access 11 Pages 2005
Relationship between constitutive nuclear factor-kappaB (NF-κB) and inhibitor kappaB-alpha (IκB-α) in an interferon-α-sensitive human Burkitt lymphoma cell line Fulltext Access 11 Pages 2005
Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background Fulltext Access 11 Pages 2005
Molecular misreading: the frequency of dinucleotide deletions in neuronal mRNAs for β-amyloid precursor protein and ubiquitin B Fulltext Access 11 Pages 2005
Temporal evolution of mouse striatal gene expression following MPTP injury Fulltext Access 11 Pages 2005
Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP Fulltext Access 11 Pages 2005
Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role Fulltext Access 11 Pages 2005
Aging affects choroidal proteins involved in CSF production in Sprague-Dawley rats Fulltext Access 11 Pages 2005
Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction Fulltext Access 11 Pages 2005
Age-related decline in caloric intake and motivation for food in rhesus monkeys Fulltext Access 11 Pages 2005
Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation Fulltext Access 11 Pages 2005
Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus Fulltext Access 11 Pages 2005
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4 Fulltext Access 11 Pages 2005
Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity Fulltext Access 11 Pages 2005
The essential mechanisms of aging: Irreparable damage accumulation of biochemical side-reactions Fulltext Access 11 Pages 2005
Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease Fulltext Access 11 Pages 2005
Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration Fulltext Access 11 Pages 2005
Soleus muscles of SAMP8 mice provide an accelerated model of skeletal muscle senescence Fulltext Access 11 Pages 2005
Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes Fulltext Access 11 Pages 2005
Neurodegenerative conditions associated with ageing: a molecular interplay? Fulltext Access 11 Pages 2005
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians Fulltext Access 11 Pages 2005
Genetic epidemiology of skeletal system aging in apparently healthy human population Fulltext Access 11 Pages 2005
Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis Fulltext Access 11 Pages 2005
Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition Fulltext Access 11 Pages 2005
The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome Fulltext Access 11 Pages 2005
Behavioral screening for nightblindness mutants in zebrafish reveals three new loci that cause dominant photoreceptor cell degeneration Fulltext Access 11 Pages 2005
Differential expression of genes associated with telomere length homeostasis and oncogenesis in an avian model Fulltext Access 11 Pages 2005
Protection against hydrogen peroxide-induced cell death in cultured human retinal pigment epithelial cells by 17β-estradiol: A differential gene expression profile Fulltext Access 11 Pages 2005
Reproductive and dietary determinants of the age at menopause in EPIC-Heidelberg Fulltext Access 11 Pages 2005