Pou1f1, the key transcription factor related to somatic growth in tilapia (Orechromis niloticus), is regulated by two independent post-transcriptional regulation mechanisms Fulltext Access 7 Pages 2017
LncRNA Gm4419 contributes to OGD/R injury of cerebral microglial cells via IκB phosphorylation and NF-κB activation Fulltext Access 7 Pages 2017
High sugar diet disrupts gut homeostasis though JNK and STAT pathways in Drosophila Fulltext Access 7 Pages 2017
Apomorphine suppresses TNF-α-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells Fulltext Access 7 Pages 2017
miR-17-92 promotes leukemogenesis in chronic myeloid leukemia via targeting A20 and activation of NF-κB signaling Fulltext Access 7 Pages 2017
Effects of matsutake mushroom scent compounds on tyrosinase and murine B16-F10 melanoma cells Fulltext Access 7 Pages 2017
Brusatol inhibits growth and induces apoptosis in pancreatic cancer cells via JNK/p38 MAPK/NF-κb/Stat3/Bcl-2 signaling pathway Fulltext Access 7 Pages 2017
Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line Fulltext Access 7 Pages 2017
Prolyl-tRNA synthetase inhibition promotes cell death in SK-MEL-2Â cells through GCN2-ATF4 pathway activation Fulltext Access 7 Pages 2017
Assessing activity of Hepatitis A virus 3C protease using a cyclized luciferase-based biosensor Fulltext Access 7 Pages 2017
Identification of miR-601 as a novel regulator in the development of pancreatic cancer Fulltext Access 7 Pages 2017
Deficiency in ubiquitin-like protein Ubl4A impairs migration of fibroblasts and macrophages Fulltext Access 7 Pages 2017
MicroRNA-340 inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting JAK1 Fulltext Access 7 Pages 2017
Resistance-breaking population of Meloidogyne incognita utilizes plant peroxidase to scavenge reactive oxygen species, thereby promoting parasitism on tomato carrying Mi-1 gene Fulltext Access 7 Pages 2017
Identification of AcAP5 as a novel factor Xa inhibitor with both direct and allosteric inhibition Fulltext Access 7 Pages 2017
The Notch ligand delta-like 3 promotes tumor growth and inhibits Notch signaling in lung cancer cells in mice Fulltext Access 7 Pages 2017
Down-regulation of MsrB3 induces cancer cell apoptosis through reactive oxygen species production and intrinsic mitochondrial pathway activation Fulltext Access 7 Pages 2017
Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells Fulltext Access 7 Pages 2017
Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation Fulltext Access 7 Pages 2017
Direct transcriptional activation of BT genes by NLP transcription factors is a key component of the nitrate response in Arabidopsis Fulltext Access 7 Pages 2017
Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice Fulltext Access 7 Pages 2017
Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2) Fulltext Access 7 Pages 2017
Biophysical characterization of Ca2+-binding of S100A5 and Ca2+-induced interaction with RAGE Fulltext Access 7 Pages 2017
Repression of miR-217 protects against high glucose-induced podocyte injury and insulin resistance by restoring PTEN-mediated autophagy pathway Fulltext Access 7 Pages 2017
Identification and characterization of novel lncRNAs in Arabidopsis thaliana Fulltext Access 7 Pages 2017
Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells Fulltext Access 7 Pages 2017
Loss of MURC/Cavin-4 induces JNK and MMP-9 activity enhancement in vascular smooth muscle cells and exacerbates abdominal aortic aneurysm Fulltext Access 7 Pages 2017
Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8) Fulltext Access 7 Pages 2017
Probing the acidic residue within the integrin binding site of laminin-511 that interacts with the metal ion-dependent adhesion site of α6β1 integrin Fulltext Access 7 Pages 2017
MafB enhances the phagocytic activity of RAW264.7 macrophages by promoting Fcgr3 expression Fulltext Access 7 Pages 2017
Ectopical expression of FABP4 gene can induce bovine muscle-derived stem cells adipogenesis Fulltext Access 7 Pages 2017
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca2+-calcineurin-NFATc1 signaling pathway Fulltext Access 7 Pages 2017
A secretome analysis reveals that PPARα is upregulated by fractionated-dose γ-irradiation in three-dimensional keratinocyte cultures Fulltext Access 7 Pages 2017
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells Fulltext Access 7 Pages 2017
Hypoxia pretreatment and EPO-modification enhance the protective effects of MSC on neuron-like PC12Â cells in a similar way Fulltext Access 7 Pages 2017
miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity Fulltext Access 7 Pages 2017
Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity Fulltext Access 7 Pages 2017
Circadian clock and steroidogenic-related gene expression profiles in mouse Leydig cells following dexamethasone stimulation Fulltext Access 7 Pages 2017
Transcriptional activation of NANOG by YBX1 promotes lung cancer stem-like properties and metastasis Fulltext Access 7 Pages 2017
SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer Fulltext Access 7 Pages 2017
Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia Fulltext Access 7 Pages 2017
Function of Nup98 subtypes and their fusion proteins, Nup98-TopIIβ and Nup98-SETBP1 in nuclear-cytoplasmic transport Fulltext Access 7 Pages 2017
Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway Fulltext Access 7 Pages 2017
MicroRNA-29 regulates myocardial microvascular endothelial cells proliferation and migration in association with IGF1 in type 2 diabetes Fulltext Access 7 Pages 2017
Transcriptional repression of HER2 by ANO1 Clâ channel inhibition in human breast cancer cells with resistance to trastuzumab Fulltext Access 7 Pages 2017
Glaucocalyxin A improves survival in bleomycin-induced pulmonary fibrosis in mice Fulltext Access 7 Pages 2017
Angiogenic factor with G patch and FHA domains 1 (Aggf1) promotes hepatic steatosis in mice Fulltext Access 7 Pages 2017
Functional characterization of archaeal homologs of human nuclear RNase P proteins Rpp21 and Rpp29 provides insights into the molecular basis of their cooperativity in catalysis Fulltext Access 7 Pages 2017
Genetic disruption of tubulin acetyltransferase, αTAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/β-catenin signaling Fulltext Access 7 Pages 2017
MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia Fulltext Access 7 Pages 2017
TRB3 gene silencing activates AMPK in adipose tissue with beneficial metabolic effects in obese and diabetic rats Fulltext Access 7 Pages 2017
Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development Fulltext Access 7 Pages 2017
JNJ10181457, a histamine H3 receptor inverse agonist, regulates in vivo microglial functions and improves depression-like behaviours in mice Fulltext Access 7 Pages 2017
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro Fulltext Access 7 Pages 2017
Differences in the effects of four TRPV1 channel antagonists on lipopolysaccharide-induced cytokine production and COX-2 expression in murine macrophages Fulltext Access 7 Pages 2017
K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology Fulltext Access 7 Pages 2017
Nickel(II) diacetyl monoxime-2-pyridyl hydrazone complex can inhibit Ehrlich solid tumor growth in mice: A potential new antitumor drug Fulltext Access 7 Pages 2017
Inhibition of Drp1 attenuates mitochondrial damage and myocardial injury in Coxsackievirus B3 induced myocarditis Fulltext Access 7 Pages 2017
4-PBA reverses autophagic dysfunction and improves insulin sensitivity in adipose tissue of obese mice via Akt/mTOR signaling Fulltext Access 7 Pages 2017
USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination Fulltext Access 7 Pages 2017
KLF4 expression enhances the efficacy of chemotherapy drugs in ovarian cancer cells Fulltext Access 7 Pages 2017
Tetrameric structure of the flagellar cap protein FliD from Serratia marcescens Fulltext Access 7 Pages 2017
Identification of repaglinide as a therapeutic drug for glioblastoma multiforme Fulltext Access 7 Pages 2017
Synergistic anti-tumor effects of bevacizumab and tumor targeted polymerized VEGF siRNA nanoparticles Fulltext Access 7 Pages 2017
AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes Fulltext Access 7 Pages 2017
Combined blockade of Tim-3 and MEK inhibitor enhances the efficacy against melanoma Fulltext Access 7 Pages 2017
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4E-hepten-3-one alleviates Aβ1-42 induced cytotoxicity through PI3K-mTOR pathways Fulltext Access 7 Pages 2017
Fluid shear stress stimulates MATE2-K expression via Nrf2 pathway activation Fulltext Access 7 Pages 2017
MicroRNA-365 accelerates cardiac hypertrophy by inhibiting autophagy via the modulation of Skp2 expression Fulltext Access 7 Pages 2017
Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions Fulltext Access 7 Pages 2017
CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse model Fulltext Access 7 Pages 2017
Conditional knockout of microRNA-31 promotes the development of colitis associated cancer Fulltext Access 7 Pages 2017
RETRACTED: Association of angiotensin II receptor 1 and lectin-like oxidized low-density lipoprotein receptor-1 mediates the cardiac hypertrophy induced by oxidized low-density lipoprotein Fulltext Access 7 Pages 2017
Berberine protects against ischemia/reperfusion injury after orthotopic liver transplantation via activating Sirt1/FoxO3α induced autophagy Fulltext Access 7 Pages 2017
Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis Fulltext Access 7 Pages 2017
Role of extracellular vesicles in the interaction between epithelial and mesenchymal cells during oviductal ciliogenesis Fulltext Access 7 Pages 2017
LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway Fulltext Access 7 Pages 2017
AtGIS, a C2H2 zinc-finger transcription factor from Arabidopsis regulates glandular trichome development through GA signaling in tobacco Fulltext Access 7 Pages 2017
The alteration of serine transporter activity in a cell line model of amyotrophic lateral sclerosis (ALS) Fulltext Access 7 Pages 2017
Structural and functional characterization of the alanine racemase from Streptomyces coelicolor A3(2) Fulltext Access 7 Pages 2017
Characterization of divergent pseudo-sucrose isomerase from Azotobacter vinelandii: Deciphering the absence of sucrose isomerase activity Fulltext Access 7 Pages 2017
Systematic time-dependent visualization and quantitation of the neurogenic rate in brain organoids Fulltext Access 7 Pages 2017
MiR-107 induces TNF-α secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury Fulltext Access 7 Pages 2017
Hypoxia promotes mitochondrial glutamine metabolism through HIF1α-GDH pathway in human lung cancer cells Fulltext Access 7 Pages 2017
Antibiotic tigecycline enhances cisplatin activity against human hepatocellular carcinoma through inducing mitochondrial dysfunction and oxidative damage Fulltext Access 7 Pages 2017
mTOR up-regulation of PFKFB3 is essential for acute myeloid leukemia cell survival Fulltext Access 7 Pages 2017
A causal relationship between the neurotherapeutic effects of miR182/7a and decreased expression of PRDM5 Fulltext Access 7 Pages 2017
NDRG2 overexpression suppresses hepatoma cells survival during metabolic stress through disturbing the activation of fatty acid oxidation Fulltext Access 7 Pages 2017
RNF8 negatively regulates NF-kappaB signaling by targeting IkappaB kinase: implications for the regulation of inflammation signaling Fulltext Access 7 Pages 2017
Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies Fulltext Access 7 Pages 2017
Crucial role of ATP-bound Sse1 in Upf1-dependent degradation of the truncated product Fulltext Access 7 Pages 2017
Role of PI3K p110β in the differentiation of human embryonic stem cells into islet-like cells Fulltext Access 7 Pages 2017
Nitric oxide modifies root growth by S-nitrosylation of plastidial glyceraldehyde-3-phosphate dehydrogenase Fulltext Access 7 Pages 2017
Long non-coding RNA FBXL19-AS1 plays oncogenic role in colorectal cancer by sponging miR-203 Fulltext Access 7 Pages 2017
Overexpression of microRNA-125b inhibits human acute myeloid leukemia cells invasion, proliferation and promotes cells apoptosis by targeting NF-κB signaling pathway Fulltext Access 7 Pages 2017
Green fluorescence protein-based content-mixing assay of SNARE-driven membrane fusion Fulltext Access 7 Pages 2017
Autophagy promotes osteogenic differentiation of human bone marrow mesenchymal stem cell derived from osteoporotic vertebrae Fulltext Access 7 Pages 2017