TGF-β1 induced fascin1 expression facilitates the migration and invasion of kidney carcinoma cells through ERK and JNK signaling pathways Fulltext Access 7 Pages 2018
CTP synthase knockdown during early development distorts the nascent vertebral column and causes fluid retention in multiple tissues in zebrafish Fulltext Access 7 Pages 2018
SGIP1 dimerizes via intermolecular disulfide bond in μHD domain during cellular endocytosis Fulltext Access 7 Pages 2018
An optimal serum-free defined condition for in vitro culture of kidney organoids Fulltext Access 7 Pages 2018
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy Fulltext Access 7 Pages 2018
PAFAH1B2 is a HIF1a target gene and promotes metastasis in pancreatic cancer Fulltext Access 7 Pages 2018
Proteasome-mediated protein degradation is enhanced by fusion ubiquitin with unstructured degron Fulltext Access 7 Pages 2018
Autophagy mediates enhancement of proangiogenic activity by hypoxia in mesenchymal stromal/stem cells Fulltext Access 7 Pages 2018
Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling Fulltext Access 7 Pages 2018
Identification and characterization of the zinc finger protein SjZF in Schistosoma japonicum Fulltext Access 7 Pages 2018
ELK1-induced upregulation of lncRNA HOXA10-AS promotes lung adenocarcinoma progression by increasing Wnt/β-catenin signaling Fulltext Access 7 Pages 2018
Circ-SATB2 upregulates STIM1 expression and regulates vascular smooth muscle cell proliferation and differentiation through miR-939 Fulltext Access 7 Pages 2018
Erybraedin A is a potential Src inhibitor that blocks the adhesion and viability of non-small-cell lung cancer cells Fulltext Access 7 Pages 2018
Crystal structure of WA352 provides insight into cytoplasmic male sterility in rice Fulltext Access 7 Pages 2018
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining Fulltext Access 7 Pages 2018
Different players generate positive responses in two in vitro cytokine assay formats with aqueous and immobilized TGN1412 analog Fulltext Access 7 Pages 2018
ATP6V1H regulates the growth and differentiation of bone marrow stromal cells Fulltext Access 7 Pages 2018
Cholesterol promotes the migration and invasion of renal carcinoma cells by regulating the KLF5/miR-27a/FBXW7 pathway Fulltext Access 7 Pages 2018
Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster Fulltext Access 7 Pages 2018
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice Fulltext Access 7 Pages 2018
Inhibition of microRNA-16 facilitates the paclitaxel resistance by targeting IKBKB via NF-κB signaling pathway in hepatocellular carcinoma Fulltext Access 7 Pages 2018
Cleavage of molybdopterin synthase MoaD-MoaE linear fusion by JAMM/MPN+ domain containing metalloprotease DR0402 from Deinococcus radiodurans Fulltext Access 7 Pages 2018
Multiple mutations in the aglycone binding pocket to convert the substrate specificity of dalcochinase to linamarase Fulltext Access 7 Pages 2018
miR-423-5p suppresses high-glucose-induced podocyte injury by targeting Nox4 Fulltext Access 7 Pages 2018
Upregulation of 24(R/S),25-epoxycholesterol and 27-hydroxycholesterol suppresses the proliferation and migration of gastric cancer cells Fulltext Access 7 Pages 2018
Gulo regulates the proliferation, apoptosis and mesenchymal-to-epithelial transformation of metanephric mesenchyme cells via inhibiting Six2 Fulltext Access 7 Pages 2018
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families Fulltext Access 7 Pages 2018
MicroRNA-613 promotes colon cancer cell proliferation, invasion and migration by targeting ATOH1 Fulltext Access 7 Pages 2018
miR-1306-3p targets FBXL5 to promote metastasis of hepatocellular carcinoma through suppressing snail degradation Fulltext Access 7 Pages 2018
Deletion of JDP2 improves neurological outcomes of traumatic brain injury (TBI) in mice: Inactivation of Caspase-3 Fulltext Access 7 Pages 2018
ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway Fulltext Access 7 Pages 2018
Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart Fulltext Access 7 Pages 2018
Dynamics of alternative polyadenylation in human preimplantation embryos Fulltext Access 7 Pages 2018
Depleting the carboxy-terminus of human Wnt5a attenuates collagen-induced arthritis in DBA/1 mice Fulltext Access 7 Pages 2018
Daunorubicin, a topoisomerase II poison, suppresses viral production of hepatitis B virus by inducing cGAS-dependent innate immune response Fulltext Access 7 Pages 2018
Overexpression of TUSC7 inhibits the inflammation caused by microglia activation via regulating miR-449a/PPAR-γ Fulltext Access 7 Pages 2018
Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method Fulltext Access 7 Pages 2018
Downregulated miR-1247-5p associates with poor prognosis and facilitates tumor cell growth via DVL1/Wnt/β-catenin signaling in breast cancer Fulltext Access 7 Pages 2018
Exploring the role of methionine residues on the oligomerization and neurotoxic properties of DOPAL-modified α-synuclein Fulltext Access 7 Pages 2018
Visualization of specific collagen-producing cells by Col1-GFP transgenic mice revealed novel type I collagen-producing cells other than fibroblasts in systemic organs/tissues Fulltext Access 7 Pages 2018
The circular RNA circ-ITCH suppresses ovarian carcinoma progression through targeting miR-145/RASA1 signaling Fulltext Access 7 Pages 2018
Integrin β1 promotes gemcitabine resistance in pancreatic cancer through Cdc42 activation of PI3K p110β signaling Fulltext Access 7 Pages 2018
Elucidation of the crystal structure of FabD from the multidrug-resistant bacterium Acinetobacter baumannii Fulltext Access 7 Pages 2018
The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca2+ signals, ERK and PI3K Fulltext Access 7 Pages 2018
Induction of apoptosis by morusin in human non-small cell lung cancer cells by suppression of EGFR/STAT3 activation Fulltext Access 7 Pages 2018
Phosphoproteomic analysis reveals PAK2 as a therapeutic target for lapatinib resistance in HER2-positive breast cancer cells Fulltext Access 7 Pages 2018
YY1-induced upregulation of lncRNA KCNQ1OT1 regulates angiotensin II-induced atrial fibrillation by modulating miR-384b/CACNA1C axis Fulltext Access 7 Pages 2018
Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A Fulltext Access 7 Pages 2018
Aspirin restores ABT-737-mediated apoptosis in human renal carcinoma cells Fulltext Access 7 Pages 2018
Mechanisms involved in epigenetic down-regulation of Gfap under maternal hypothyroidism Fulltext Access 7 Pages 2018
Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells Fulltext Access 7 Pages 2018
Circular RNA HIPK3 promotes gallbladder cancer cell growth by sponging microRNA-124 Fulltext Access 7 Pages 2018
SIRT1 promotes proliferation, migration, and invasion of breast cancer cell line MCF-7 by upregulating DNA polymerase delta1 (POLD1) Fulltext Access 7 Pages 2018
Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation Fulltext Access 7 Pages 2018
Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice Fulltext Access 7 Pages 2018
Long non-coding RNA MALAT1 interacts with transcription factor Foxo1 to regulate SIRT1 transcription in high glucose-induced HK-2â¯cells injury Fulltext Access 7 Pages 2018
LRP4 promotes proliferation, migration, and invasion in papillary thyroid cancer Fulltext Access 7 Pages 2018
SKLPT imaging: Efficient in vivo pre-evaluation of genome-editing modules using fluorescent protein with peroxisome targeting signal Fulltext Access 7 Pages 2018
MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex Fulltext Access 7 Pages 2018
HIF-1α induces immune escape of prostate cancer by regulating NCR1/NKp46 signaling through miR-224 Fulltext Access 7 Pages 2018
Lactic acid induces lactate transport and glycolysis/OXPHOS interconversion in glioblastoma Fulltext Access 7 Pages 2018
Increase of SOX9 promotes hepatic ischemia/reperfusion (IR) injury by activating TGF-β1 Fulltext Access 7 Pages 2018
Long noncoding RNA ANCR suppresses bone formation of periodontal ligament stem cells via sponging miRNA-758 Fulltext Access 7 Pages 2018
Alternative translation initiation from two in-frame start codons in DHX33 gene Fulltext Access 7 Pages 2018
Inhibition of TBK1 reduces choroidal neovascularization in vitro and in vivo Fulltext Access 7 Pages 2018
miRNA editing landscape reveals miR-34c regulated spermatogenesis through structure and target change in pig and mouse Fulltext Access 7 Pages 2018
Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference Fulltext Access 7 Pages 2018
17β-estradiol protects nucleus pulposus cells from serum deprivation-induced apoptosis and regulates expression of MMP-3 and MMP-13 through promotion of autophagy Fulltext Access 7 Pages 2018
9-cis-retinoic acid elevates MRP3 expression by inhibiting sumoylation of RXRα to alleviate cholestatic liver injury Fulltext Access 7 Pages 2018
Ectopic expression of the TAL effector AvrXa7 in Xanthomonas citri subsp. citri hinders citrus canker symptom formation by modulating transcriptional profile of citrus genes Fulltext Access 7 Pages 2018
Synthesis and detoxification of nitric oxide in the plant beneficial rhizobacterium Bacillus amyloliquefaciens SQR9 and its effect on biofilm formation Fulltext Access 7 Pages 2018
Anti-viral immune response in the lung and thymus: Molecular characterization and expression analysis of immunoproteasome subunits LMP2, LMP7 and MECL-1 in pigs Fulltext Access 7 Pages 2018
A preliminary study of photoacoustic/ultrasound dual-mode imaging in melanoma using MAGE-targeted gold nanoparticles Fulltext Access 7 Pages 2018
RNA interference in vivo in Schistosoma japonicum: Establishing and optimization of RNAi mediated suppression of gene expression by long dsRNA in the intra-mammalian life stages of worms Fulltext Access 7 Pages 2018
Amelioration of myocardial ischemia-reperfusion injury by SIRT4 involves mitochondrial protection and reduced apoptosis Fulltext Access 7 Pages 2018
The E3 ubiquitin ligase RNF146 promotes colorectal cancer by activating the Wnt/β-catenin pathway via ubiquitination of Axin1 Fulltext Access 7 Pages 2018
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy Fulltext Access 7 Pages 2018
MicroRNA 148a-3p promotes Thrombospondin-4 expression and enhances angiogenesis during tendinopathy development by inhibiting Krüppel-like factor 6 Fulltext Access 7 Pages 2018
Neuregulin-4 is an angiogenic factor that is critically involved in the maintenance of adipose tissue vasculature Fulltext Access 7 Pages 2018
YY1 promotes IL-6 expression in LPS-stimulated BV2 microglial cells by interacting with p65 to promote transcriptional activation of IL-6 Fulltext Access 7 Pages 2018
Loss of virulence in NAD(P)H cytochrome b5 oxidoreductase deficient Leishmania major Fulltext Access 7 Pages 2018
Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice Fulltext Access 7 Pages 2018
The long non-coding RNA PCSEAT exhibits an oncogenic property in prostate cancer and functions as a competing endogenous RNA that associates with EZH2 Fulltext Access 7 Pages 2018
Overexpressing circular RNA hsa_circ_0002052 impairs osteosarcoma progression via inhibiting Wnt/β-catenin pathway by regulating miR-1205/APC2 axis Fulltext Access 7 Pages 2018
Amide-linked local anesthetics preferentially target leukemia stem cell through inhibition of Wnt/β-catenin Fulltext Access 7 Pages 2018
Expression of ZO1, vimentin, pan-cadherin and AGTR1 in tanycyte-like cells of the sulcus medianus organum Fulltext Access 7 Pages 2018
Enhancement of neuronal differentiation by using small molecules modulating Nodal/Smad, Wnt/β-catenin, and FGF signaling Fulltext Access 7 Pages 2018
Readthrough of ACTN3 577X nonsense mutation produces full-length α-actinin-3 protein Fulltext Access 7 Pages 2018
Mechanical stress to Drosophila larvae stimulates a cellular immune response through the JAK/STAT signaling pathway Fulltext Access 7 Pages 2018
miRNA-mediated apoptosis activation through TMEM 48 inhibition in A549 cell line Fulltext Access 7 Pages 2018
Allethrin and prallethrin stimulates MUC5AC expression through oxidative stress in human airway epithelial cells Fulltext Access 7 Pages 2018
Anti-melanogenic activity of schaftoside in Rhizoma Arisaematis by increasing autophagy in B16F1 cells Fulltext Access 7 Pages 2018
PTP1B promotes the malignancy of ovarian cancer cells in a JNK-dependent mechanism Fulltext Access 7 Pages 2018
Delavatine A, an unusual isoquinoline alkaloid exerts anti-inflammation on LPS-induced proinflammatory cytokines production by suppressing NF-κB activation in BV-2 microglia Fulltext Access 7 Pages 2018
Histone methyltransferase SETD2 regulates osteosarcoma cell growth and chemosensitivity by suppressing Wnt/β-catenin signaling Fulltext Access 7 Pages 2018