Cell membrane-bound CD200 signals both via an extracellular domain and following nuclear translocation of a cytoplasmic fragment Fulltext Access 9 Pages 2018
Economic impact of preventing brain metastases with alectinib in ALK-positive non-small cell lung cancer Fulltext Access 9 Pages 2018
Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance Fulltext Access 9 Pages 2018
Functional cooperation between HIF-1α and c-Jun in mediating primary and acquired resistance to gefitinib in NSCLC cells with activating mutation of EGFR Fulltext Access 9 Pages 2018
Cost-effectiveness of low-dose CT screening for lung cancer in a European country with high prevalence of smoking-A modelling study Fulltext Access 9 Pages 2018
Nivolumab in advanced non-small-cell lung cancer patients who failed prior platinum-based chemotherapy Fulltext Access 9 Pages 2018
HOXA9 methylation and blood vessel invasion in FFPE tissues for prognostic stratification of stage I lung adenocarcinoma patients Fulltext Access 9 Pages 2018
The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer Fulltext Access 9 Pages 2018
Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer Fulltext Access 9 Pages 2018
Inhibition of sonic hedgehog signaling blocks cell migration and growth but induces apoptosis via suppression of FOXQ1 in natural killer/T-cell lymphoma Fulltext Access 9 Pages 2018
Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia Fulltext Access 9 Pages 2018
The combination of TRAIL and MG-132 induces apoptosis in both TRAIL-sensitive and TRAIL-resistant human follicular lymphoma cells Fulltext Access 9 Pages 2018
Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients Fulltext Access 9 Pages 2018
HER2 copy number of circulating tumour DNA functions as a biomarker to predict and monitor trastuzumab efficacy in advanced gastric cancer Fulltext Access 9 Pages 2018
Long-term efficacy analysis of the randomised, phase II TRYPHAENA cardiac safety study: Evaluating pertuzumab and trastuzumab plus standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive ea Fulltext Access 9 Pages 2018
3-Methoxytyramine: An independent prognostic biomarker that associates with high-risk disease and poor clinical outcome in neuroblastoma patients Fulltext Access 9 Pages 2018
A randomised phase II trial of docetaxel versus docetaxel plus carboplatin in patients with castration-resistant prostate cancer who have progressed after response to prior docetaxel chemotherapy: The RECARDO trial Fulltext Access 9 Pages 2018
Kinetics and nadir of responses to immune checkpoint blockade by anti-PD1 in patients with classical Hodgkin lymphoma Fulltext Access 9 Pages 2018
Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study Fulltext Access 9 Pages 2018
Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival Fulltext Access 9 Pages 2018
PICCA study: panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer-a randomised biomarker-driven clinical phase II AIO study Fulltext Access 9 Pages 2018
Randomised phase III trial of concurrent chemoradiotherapy with extended nodal irradiation and erlotinib in patients with inoperable oesophageal squamous cell cancer Fulltext Access 9 Pages 2018
A Quantitative Evaluation of MIRU-VNTR Typing Against Whole-Genome Sequencing for Identifying Mycobacterium tuberculosis Transmission: A Prospective Observational Cohort Study Fulltext Access 9 Pages 2018
Genomic aberrations involving 12p/ETV6 are highly prevalent in blastic plasmacytoid dendritic cell neoplasms and might represent early clonal events Fulltext Access 9 Pages 2018
Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTALÂ and COIN-B trials in the ARCAD databa Fulltext Access 9 Pages 2018
Optimal human iPS cell culture method for efficient hepatic differentiation Fulltext Access 9 Pages 2018
Expression of the miR-150 tumor suppressor is restored by and synergizes with rapamycin in a human leukemia T-cell line Fulltext Access 9 Pages 2018
Apport de la radiothérapie guidée par l'image et repositionnement du patient dans le cancer anorectal Fulltext Access 9 Pages 2018
Apport du guidage par l'image pour le repositionnement au cours de la radiothérapie des tumeurs encéphaliques Fulltext Access 9 Pages 2018
Surgical quality assurance in head and neck cancer trials: an EORTC Head and Neck Cancer Group position paper based on the EORTC 1420 'Best of' and 24954 'larynx preservation' study Fulltext Access 9 Pages 2018
Adjuvant dose-dense doxorubicin-cyclophosphamide versus docetaxel-doxorubicin-cyclophosphamide for high-risk breast cancer: First results of the randomised MATADOR trial (BOOG 2004-04) Fulltext Access 9 Pages 2018
Ãvolutions dans la prise en charge des métastases ganglionnaires cervicales sans cancer primitif retrouvé : doses et volumes cibles de la radiothérapie avec modulation d'intensité Fulltext Access 9 Pages 2018
Multimodality imaging using PET/CT (18F)-fluorodeoxyglucose for radiotherapy field delineation of localized Hodgkin lymphoma Fulltext Access 9 Pages 2018
Goal Directed and Self-Control Systems in Bulimia Nervosa: An fMRI Study Fulltext Access 9 Pages 2018
Integrative expression quantitative trait locus-based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression Fulltext Access 9 Pages 2018
BKV, CMV, and EBV Interactions and their Effect on Graft Function One Year Post-Renal Transplantation: Results from a Large Multi-Centre Study Fulltext Access 9 Pages 2018
Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell Renal Carcinoma and the Antitumor Effects of SBI-0206965 Fulltext Access 9 Pages 2018
Development and Validation of an MRI-Based Radiomics Signature for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer Fulltext Access 9 Pages 2018
Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR Fulltext Access 9 Pages 2018
Polo-like kinase 1 inhibitor BI 6727 induces DNA damage and exerts strong antitumor activity in small cell lung cancer Fulltext Access 9 Pages 2018
In vivo antimutagenic and antiatherogenic effects of the (1â¯ââ¯3)(1â¯ââ¯6)-β-d- glucan botryosphaeran Fulltext Access 9 Pages 2018
Assessment of the predictive capacity of the optimized in vitro comet assay using HepG2 cells Fulltext Access 9 Pages 2018
Kinetics of ROS generation induced by polycyclic aromatic hydrocarbons and organic extracts from ambient air particulate matter in model human lung cell lines Fulltext Access 9 Pages 2018
Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique Fulltext Access 9 Pages 2018
Drosophila bendless catalyzes K63-linked polyubiquitination and is involved in the response to DNA damage Fulltext Access 9 Pages 2018
Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage Fulltext Access 9 Pages 2018
Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth Fulltext Access 9 Pages 2018
Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination Fulltext Access 9 Pages 2018
Safety and clinical activity of atezolizumab monotherapy in metastatic non-small-cell lung cancer: final results from a phase I study Fulltext Access 9 Pages 2018
Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy Fulltext Access 9 Pages 2018
Treatment and outcomes of patients in the Brain Metastases in Breast Cancer Network Registry Fulltext Access 9 Pages 2018
Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment Fulltext Access 9 Pages 2018
Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma Fulltext Access 9 Pages 2018
Potential Diagnostic Power of Blood Circular RNA Expression in Active Pulmonary Tuberculosis Fulltext Access 9 Pages 2018
Low Bioavailability and High Immunogenicity of a New Brand of E. colil-Asparaginase with Active Host Contaminating Proteins Fulltext Access 9 Pages 2018
Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer Fulltext Access 9 Pages 2018
Plectin-1 Targeted Dual-modality Nanoparticles for Pancreatic Cancer Imaging Fulltext Access 9 Pages 2018
Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ Fulltext Access 9 Pages 2018
Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma Fulltext Access 9 Pages 2018
Impact of primary tumour location and RAS/BRAF mutational status in metastatic colorectal cancer treated with first-line regimens containing oxaliplatin and bevacizumab: Prognostic factors from the AIO KRK0207 first-line and maintenance therapy trial Fulltext Access 9 Pages 2018
Réirradiation des tumeurs de la tête et du cou : volumes cibles, évolutions techniques et perspectives Fulltext Access 9 Pages 2018
Metastatic mediastinal mature teratoma with malignant transformation in a young man with an adenocarcinoma in a Klinefelter's syndrome: Case report and review of the literature Fulltext Access 9 Pages 2018
Long noncoding RNA LINC00675 enhances phosphorylation of vimentin on Ser83 to suppress gastric cancer progression Fulltext Access 9 Pages 2018
High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma Fulltext Access 9 Pages 2018
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Fulltext Access 9 Pages 2018
Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma Fulltext Access 9 Pages 2018
DRR1 promotes glioblastoma cell invasion and epithelial-mesenchymal transition via regulating AKT activation Fulltext Access 9 Pages 2018
Efficacy and safety of single-agent pan-human epidermal growth factor receptor (HER) inhibitor dacomitinib in locally advanced unresectable or metastatic skin squamous cell cancer Fulltext Access 9 Pages 2018
A phase III study comparing SB3 (a proposed trastuzumab biosimilar) and trastuzumab reference product in HER2-positive early breast cancer treated with neoadjuvant-adjuvant treatment: Final safety, immunogenicity and survival results Fulltext Access 9 Pages 2018
Efficacy of gemcitabine plus erlotinib in rash-positive patients with metastatic pancreatic cancer selected according to eligibility for FOLFIRINOX: A prospective phase II study of the 'Arbeitsgemeinschaft Internistische Onkologie' Fulltext Access 9 Pages 2018
Adjuvant zoledronic acid reduces fractures in breast cancer patients; an AZURE (BIG 01/04) study Fulltext Access 9 Pages 2018
Is alpha-fetoprotein decline a prognostic factor of childhood non-seminomatous germ cell tumours? Results of the French TGM95 study Fulltext Access 9 Pages 2018
Endocrine therapy or chemotherapy as first-line therapy in hormone receptor-positive HER2-negative metastatic breast cancer patients Fulltext Access 9 Pages 2018
Comparable results of autologous and allogeneic haematopoietic stem cell transplantation for adults with Philadelphia-positive acute lymphoblastic leukaemia in first complete molecular remission: An analysis by the Acute Leukemia Working Party of the EBMT Fulltext Access 9 Pages 2018
Diagnostic value of 18F-fluordesoxyglucose positron emission tomography for patients with brain metastasis from unknown primary site Fulltext Access 9 Pages 2018
Influence of side-effects on early therapy persistence with letrozole in post-menopausal patients with early breast cancer: Results of the prospective EvAluate-TM study Fulltext Access 9 Pages 2018
A randomised phase II trial of capecitabine plus cisplatin versus S-1 plus cisplatin as a first-line treatment for advanced gastric cancer: Capecitabine plus cisplatin ascertainment versus S-1 plus cisplatin randomised PII trial (XParTS II) Fulltext Access 9 Pages 2018
Geriatric analysis from PRODIGE 20 randomized phase II trial evaluating bevacizumab + chemotherapy versus chemotherapy alone in older patients with untreated metastatic colorectal cancer Fulltext Access 9 Pages 2018
Overweight is associated to a better prognosis in metastatic colorectal cancer: A pooled analysis of FFCD trials Fulltext Access 9 Pages 2018
Efficacy and safety of regorafenib compared to placebo and to post-cross-over regorafenib in advanced non-adipocytic soft tissue sarcoma Fulltext Access 9 Pages 2018
Clinical consequences of chemotherapy dose reduction in obese patients with stage III colon cancer: A retrospective analysis from the PETACC 3 study Fulltext Access 9 Pages 2018
The EORTC CAT Core-The computer adaptive version of the EORTC QLQ-C30 questionnaire Fulltext Access 9 Pages 2018
Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations Fulltext Access 9 Pages 2018
Use of nivolumab in elderly patients with advanced squamous non-small-cell lung cancer: results from the Italian cohort of an expanded access programme Fulltext Access 9 Pages 2018
Stereotactic radiation therapy in the strategy of treatment of metastatic renal cell carcinoma: A study of the Getug group Fulltext Access 10 Pages 2018
A randomised-controlled trial of 1-year adjuvant chemotherapy with oral tegafur-uracil versus surgery alone in stage II colon cancer: SACURA trial Fulltext Access 10 Pages 2018
Advanced cutaneous squamous cell carcinoma: A retrospective analysis of patient profiles and treatment patterns-Results of a non-interventional study of the DeCOG Fulltext Access 10 Pages 2018
The role of genomic profiling in adolescents and young adults (AYAs) with advanced cancer participating in phase I clinical trials Fulltext Access 10 Pages 2018
Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis Fulltext Access 10 Pages 2018
A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer Fulltext Access 10 Pages 2018
First-line mFOLFOX plus cetuximab followed by mFOLFOX plus cetuximab or single-agent cetuximab as maintenance therapy in patients with metastatic colorectal cancer: Phase II randomised MACRO2 TTD study Fulltext Access 10 Pages 2018
The role of immune microenvironment in small-cell lung cancer: Distribution of PD-L1 expression and prognostic role of FOXP3-positive tumour infiltrating lymphocytes Fulltext Access 10 Pages 2018