Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International CardioOncology Society-one trial Fulltext Access 12 Pages 2018
Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events Fulltext Access 12 Pages 2018
Arginine inhibits the malignant transformation induced by interferon-gamma through the NF-κB-GCN2/eIF2α signaling pathway in mammary epithelial cells in vitro and in vivo Fulltext Access 12 Pages 2018
Silencing PFKP inhibits starvation-induced autophagy, glycolysis, and epithelial mesenchymal transition in oral squamous cell carcinoma Fulltext Access 12 Pages 2018
Analysis of NRAS gain in 657 patients with melanoma and evaluation of its sensitivity to a MEK inhibitor Fulltext Access 12 Pages 2018
Fatty Acid Metabolism is Associated With Disease Severity After H7N9 Infection Fulltext Access 12 Pages 2018
Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging Fulltext Access 12 Pages 2018
A Genomic-clinicopathologic Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer Fulltext Access 12 Pages 2018
Integrative (epi) Genomic Analysis to Predict Response to Androgen-Deprivation Therapy in Prostate Cancer Fulltext Access 12 Pages 2018
MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors Fulltext Access 12 Pages 2018
The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model Fulltext Access 12 Pages 2018
Hydroxylase Activity of ASPH Promotes Hepatocellular Carcinoma Metastasis Through Epithelial-to-Mesenchymal Transition Pathway Fulltext Access 12 Pages 2018
Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma Fulltext Access 12 Pages 2018
Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis Fulltext Access 12 Pages 2018
IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal Fulltext Access 12 Pages 2018
Prognostic relevance of distant metastases versus locally advanced disease in soft tissue sarcomas: An EORTC-STBSG database study Fulltext Access 12 Pages 2018
GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes Fulltext Access 12 Pages 2018
The tyrosine kinase inhibitor crizotinib does not have clinically meaningful activity in heavily pre-treated patients with advanced alveolar rhabdomyosarcoma with FOXO rearrangement: European Organisation for Research and Treatment of Cancer phase 2 trial Fulltext Access 12 Pages 2018
Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family Fulltext Access 12 Pages 2018
Dasatinib sensitises KRAS-mutant cancer cells to mitogen-activated protein kinase kinase inhibitor via inhibition of TAZ activity Fulltext Access 12 Pages 2018
Assessing the impact of benzo[a]pyrene with the in vitro fish gut model: An integrated approach for eco-genotoxicological studies Fulltext Access 12 Pages 2018
A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs Fulltext Access 12 Pages 2018
Early antioxidant responses via the concerted activation of NF-κB and Nrf2 characterize the gamma-radiation-induced adaptive response in quiescent human peripheral blood mononuclear cells Fulltext Access 12 Pages 2018
ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma Fulltext Access 12 Pages 2018
Image-guided tumour biopsies in a prospective molecular triage study (MOSCATO-01): What are the real risks? Fulltext Access 12 Pages 2018
Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing Fulltext Access 12 Pages 2018
Treatment of Del17p and/or aberrant TP53 chronic lymphocytic leukemia in the era of novel therapies Fulltext Access 12 Pages 2018
Reduced intensity is preferred over myeloablative conditioning allogeneic HCT in chronic lymphocytic leukemia whenever indicated: A systematic review/meta-analysis Fulltext Access 12 Pages 2018
A statistical approach for analyzing data from the in vivo Pig-a gene mutation assay Fulltext Access 12 Pages 2018
Place de la radiothérapie stéréotaxique extracrânienne dans la prise en charge des patients atteints de cancer Fulltext Access 12 Pages 2018
Extracellular Vesicles Secreted by Human Adipose-derived Stem Cells (hASCs) Improve Survival Rate of Rats with Acute Liver Failure by Releasing lncRNA H19 Fulltext Access 12 Pages 2018
Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells Fulltext Access 12 Pages 2018
The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice Fulltext Access 12 Pages 2018
Novel cancer gene variants and gene fusions of triple-negative breast cancers (TNBCs) reveal their molecular diversity conserved in the patient-derived xenograft (PDX) model Fulltext Access 12 Pages 2018
HDAC inhibitor suppresses proliferation and tumorigenicity of drug-resistant chronic myeloid leukemia stem cells through regulation of hsa-miR-196a targeting BCR/ABL1 Fulltext Access 12 Pages 2018
γ-Taxilin temporally regulates centrosome disjunction in a Nek2A-dependent manner Fulltext Access 12 Pages 2018
Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer Fulltext Access 12 Pages 2018
Reprogramming tumor stroma using an endogenous lipid lipoxin A4 to treat pancreatic cancer Fulltext Access 12 Pages 2018
Inhibition of the mitochondrial calcium uniporter prevents IL-13 and allergen-mediated airway epithelial apoptosis and loss of barrier function Fulltext Access 12 Pages 2018
Up-regulated miR-548k promotes esophageal squamous cell carcinoma progression via targeting long noncoding RNA-LET Fulltext Access 12 Pages 2018
Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel Fulltext Access 12 Pages 2018
Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation Fulltext Access 12 Pages 2018
Palbociclib enhances radiosensitivity of hepatocellular carcinoma and cholangiocarcinoma via inhibiting ataxia telangiectasia-mutated kinase-mediated DNA damage response Fulltext Access 13 Pages 2018
FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway Fulltext Access 13 Pages 2018
Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats Fulltext Access 13 Pages 2018
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy-Resistant Glioblastoma Fulltext Access 13 Pages 2018
Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs Fulltext Access 13 Pages 2018
Prognostic impact of elevated pretreatment serum ferritin in patients with high-risk MDS treated with azacitidine Fulltext Access 13 Pages 2018
CXCR3 expression in colorectal cancer cells enhanced invasion through preventing CXCR4 internalization Fulltext Access 13 Pages 2018
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity Fulltext Access 13 Pages 2018
ESTRO ACROP consensus guideline on CT- and MRI-based target volume delineation for primary radiation therapy of localized prostate cancer Fulltext Access 13 Pages 2018
The European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology guidelines for the management of patients with cervical cancer Fulltext Access 13 Pages 2018
γH2AX is increased in peripheral blood lymphocytes of Alzheimer's disease patients in the South Australian Neurodegeneration, Nutrition and DNA Damage (SAND) study of aging Fulltext Access 13 Pages 2018
PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma Fulltext Access 13 Pages 2018
Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth Fulltext Access 13 Pages 2018
In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile-Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa Fulltext Access 13 Pages 2018
BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells Fulltext Access 13 Pages 2018
Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation Fulltext Access 13 Pages 2018
Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor Fulltext Access 13 Pages 2018
Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation Fulltext Access 13 Pages 2018
DNA damage in rats with streptozotocin-induced diabetes; protective effect of silibinin Fulltext Access 13 Pages 2018
SEC-induced activation of ANXA7 GTPase suppresses prostate cancer metastasis Fulltext Access 13 Pages 2018
Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo Fulltext Access 13 Pages 2018
Bidirectional juxtacrine ephrinB2/Ephs signaling promotes angiogenesis of ECs and maintains self-renewal of MSCs Fulltext Access 13 Pages 2018
Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy Fulltext Access 13 Pages 2018
One-pot synthesis of pH-responsive charge-switchable PEGylated nanoscale coordination polymers for improved cancer therapy Fulltext Access 13 Pages 2018
Engineering detoxified pneumococcal pneumolysin derivative ÎA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models Fulltext Access 13 Pages 2018
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles Fulltext Access 13 Pages 2018
Effects of manganese toxicity on the protein profile of tomato (Solanum lycopersicum) roots as revealed by two complementary proteomic approaches, two-dimensional electrophoresis and shotgun analysis Fulltext Access 13 Pages 2018
N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas Fulltext Access 13 Pages 2018
USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma Fulltext Access 13 Pages 2018
The TGFβ-induced lncRNA TBILA promotes non-small cell lung cancer progression in vitro and in vivo via cis-regulating HGAL and activating S100A7/JAB1 signaling Fulltext Access 13 Pages 2018
Perspectives on the physiological roles of microRNAs in immune-metabolism: Where are we now? Fulltext Access 13 Pages 2018
Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress Fulltext Access 13 Pages 2018
Imaging of human epidermal growth factor receptors for patient selection and response monitoring - From PET imaging and beyond Fulltext Access 13 Pages 2018
Palmatine suppresses glutamine-mediated interaction between pancreatic cancer and stellate cells through simultaneous inhibition of survivin and COL1A1 Fulltext Access 13 Pages 2018
Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura Fulltext Access 13 Pages 2018
Flubendazole overcomes trastuzumab resistance by targeting cancer stem-like properties and HER2 signaling in HER2-positive breast cancer Fulltext Access 13 Pages 2018
Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens Fulltext Access 13 Pages 2018
The role of gastrulation brain homeobox 2 (gbx2) in the development of the ventral telencephalon in zebrafish embryos Fulltext Access 13 Pages 2018
Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation Fulltext Access 13 Pages 2018
Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling Fulltext Access 13 Pages 2018
Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders Fulltext Access 13 Pages 2018
Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue Fulltext Access 13 Pages 2018
T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties Fulltext Access 13 Pages 2018
Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis Fulltext Access 13 Pages 2018
Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages Fulltext Access 13 Pages 2018
Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells Fulltext Access 13 Pages 2018
Construction of humanized anti-HER2 single-chain variable fragments (husFvs) and achievement of potent tumor suppression with the reconstituted husFv-Fdt-tBid immunoapoptotin Fulltext Access 13 Pages 2018
The GNASR201C mutation associated with clonal hematopoiesis supports transplantable hematopoietic stem cell activity Fulltext Access 13 Pages 2018
Incidence, risk factors and prognostic characteristics of bone metastases and skeletal-related events (SREs) in breast cancer patients: A systematic review of the real world data Fulltext Access 13 Pages 2018