Phenotyping and Target Expression Profiling of CD34+/CD38â and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia Fulltext Access 11 Pages 2018
Rapamycin Synergizes with Cisplatin in Antiendometrial Cancer Activation by Improving IL-27-Stimulated Cytotoxicity of NK Cells Fulltext Access 11 Pages 2018
Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia Fulltext Access 11 Pages 2018
IDH1R132H Promotes Malignant Transformation of Benign Prostatic Epithelium by Dysregulating MicroRNAs: Involvement of IGF1R-AKT/STAT3 Signaling Pathway Fulltext Access 11 Pages 2018
A Heparin Binding Motif Rich in Arginine and Lysine is the Functional Domain of YKL-40 Fulltext Access 11 Pages 2018
Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression Fulltext Access 11 Pages 2018
COX-2 Forms Regulatory Loop with YAP to Promote Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells Fulltext Access 11 Pages 2018
Novel Regulatory Roles of Wnt1 in Infection-Associated Colorectal Cancer Fulltext Access 11 Pages 2018
Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer Fulltext Access 11 Pages 2018
Concomitant BCORL1 and BRAF Mutations in Vemurafenib-Resistant Melanoma Cells Fulltext Access 11 Pages 2018
Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma Fulltext Access 11 Pages 2018
A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors Fulltext Access 11 Pages 2018
Prognostic Significance of CSN2, CD8, and MMR Status-Associated Nomograms in Patients with Colorectal Cancer Fulltext Access 11 Pages 2018
DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts Fulltext Access 11 Pages 2018
Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2 Fulltext Access 11 Pages 2018
Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression Fulltext Access 11 Pages 2018
Eukaryotic DNA damage responses: Homologous recombination factors and ubiquitin modification Fulltext Access 11 Pages 2018
A patient with malignant pleural mesothelioma carrying BRAF V600E mutation responding to vemurafenib Fulltext Access 11 Pages 2018
Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms Fulltext Access 11 Pages 2018
Anti-CD19 chimeric antigen receptor targeting of CD19â¯+â¯acute myeloid leukemia Fulltext Access 11 Pages 2018
The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant Fulltext Access 11 Pages 2018
Targeting the IL-17/IL-6 axis can alter growth of Chronic Lymphocytic Leukemia in vivo/in vitro Fulltext Access 11 Pages 2018
A systematic review of patient reported outcomes in phase II or III clinical trials of myelodysplastic syndromes and acute myeloid leukemia Fulltext Access 11 Pages 2018
Association of fasting serum glucose level and type 2 diabetes with hepatocellular carcinoma in men with chronic hepatitis B infection: A large cohort study Fulltext Access 11 Pages 2018
PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents Fulltext Access 11 Pages 2018
The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer Fulltext Access 11 Pages 2018
Circulating tumour DNA is a potential biomarker for disease progression and response to targeted therapy in advanced thyroid cancer Fulltext Access 11 Pages 2018
UCBG 2-08: 5-year efficacy results from the UNICANCER-PACS08 randomised phase III trial of adjuvant treatment with FEC100 and then either docetaxel or ixabepilone in patients with early-stage, poor prognosis breast cancer Fulltext Access 11 Pages 2018
Expression of the Immune Checkpoint Modulator OX40 in Acute Lymphoblastic Leukemia Is Associated with BCR-ABL Positivity Fulltext Access 11 Pages 2018
Predictors of prolonged benefit from palbociclib plus fulvestrant in women with endocrine-resistant hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer in PALOMA-3 Fulltext Access 11 Pages 2018
Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis Fulltext Access 11 Pages 2018
How to MEK the best of uveal melanoma: A systematic review on the efficacy and safety of MEK inhibitors in metastatic or unresectable uveal melanoma Fulltext Access 11 Pages 2018
Estrogen/GPR30 Signaling Contributes to the Malignant Potentials of ER-Negative Cervical Adenocarcinoma via Regulation of Claudin-1 Expression Fulltext Access 11 Pages 2018
Chemotherapeutic Treatments Increase PD-L1 Expression in Esophageal Squamous Cell Carcinoma through EGFR/ERK Activation Fulltext Access 11 Pages 2018
BTLA marks a less cytotoxic T-cell subset in diffuse large B-cell lymphoma with high expression of checkpoints Fulltext Access 11 Pages 2018
Effects of ionizing radiation and HPSE1 inhibition on the invasion of oral tongue carcinoma cells on human extracellular matrices in vitro Fulltext Access 11 Pages 2018
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer Fulltext Access 11 Pages 2018
DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling Fulltext Access 11 Pages 2018
IFN-γ Induces Gastric Cancer Cell Proliferation and Metastasis Through Upregulation of Integrin β3-Mediated NF-κB Signaling Fulltext Access 11 Pages 2018
Machine Learning Based Prediction of Brain Metastasis of Patients with IIIA-N2 Lung Adenocarcinoma by a Three-miRNA Signature Fulltext Access 11 Pages 2018
The Chemokine Receptor CXCR4 and c-MET Cooperatively Promote Epithelial-Mesenchymal Transition in Gastric Cancer Cells Fulltext Access 11 Pages 2018
Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment Fulltext Access 11 Pages 2018
Biphasic Alteration of Butyrylcholinesterase (BChE) During Prostate Cancer Development Fulltext Access 11 Pages 2018
p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer Fulltext Access 11 Pages 2018
Hydrogen Sulfide Demonstrates Promising Antitumor Efficacy in Gastric Carcinoma by Targeting MGAT5 Fulltext Access 11 Pages 2018
Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion Fulltext Access 11 Pages 2018
Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer Fulltext Access 11 Pages 2018
Oligodendrocyte Progenitor Cells and Macrophages/Microglia Produce Glioma Stem Cell Niches at the Tumor Border Fulltext Access 11 Pages 2018
A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study Fulltext Access 11 Pages 2018
RankProd Combined with Genetic Algorithm Optimized Artificial Neural Network Establishes a Diagnostic and Prognostic Prediction Model that Revealed C1QTNF3 as a Biomarker for Prostate Cancer Fulltext Access 11 Pages 2018
Gefitinib for Epidermal Growth Factor Receptor Activated Osteoarthritis Subpopulation Treatment Fulltext Access 11 Pages 2018
TGF-β3 Promotes MUC5AC Hyper-Expression by Modulating Autophagy Pathway in Airway Epithelium Fulltext Access 11 Pages 2018
Immune Characteristics of Chinese Diffuse Large B-Cell Lymphoma Patients: Implications for Cancer Immunotherapies Fulltext Access 11 Pages 2018
Lnc-PCDH9-13:1 Is a Hypersensitive and Specific Biomarker for Early Hepatocellular Carcinoma Fulltext Access 11 Pages 2018
Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice Fulltext Access 11 Pages 2018
How the Warburg effect supports aggressiveness and drug resistance of cancer cells? Fulltext Access 11 Pages 2018
N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy Fulltext Access 11 Pages 2018
MLKL-PITPα signaling-mediated necroptosis contributes to cisplatin-triggered cell death in lung cancer A549 cells Fulltext Access 11 Pages 2018
Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals Fulltext Access 11 Pages 2018
Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma Fulltext Access 11 Pages 2018
FOXF2 deficiency permits basal-like breast cancer cells to form lymphangiogenic mimicry by enhancing the response of VEGF-C/VEGFR3 signaling pathway Fulltext Access 11 Pages 2018
Combined inhibition of PI3Kδ and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia Fulltext Access 11 Pages 2018
LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85 Fulltext Access 11 Pages 2018
LncRNA n335586/miR-924/CKMT1A axis contributes to cell migration and invasion in hepatocellular carcinoma cells Fulltext Access 11 Pages 2018
MiRNAs: dynamic regulators of immune cell functions in inflammation and cancer Fulltext Access 11 Pages 2018
Pharmacologic inhibition of AKT leads to cell death in relapsed multiple myeloma Fulltext Access 11 Pages 2018
Delivery of MGMT mRNA to glioma cells by reactive astrocyte-derived exosomes confers a temozolomide resistance phenotype Fulltext Access 11 Pages 2018
Nemo-like kinase (NLK) primes colorectal cancer progression by releasing the E2F1 complex from HDAC1 Fulltext Access 11 Pages 2018
Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon Fulltext Access 11 Pages 2018
Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update Fulltext Access 11 Pages 2018
Aberrant determination of phenotypic markers in chronic lymphocytic leukemia (CLL) lymphocytes after cryopreservation Fulltext Access 11 Pages 2018
Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase Fulltext Access 11 Pages 2018
Tsc1-dependent transcriptional programming of dendritic cell homeostasis and function Fulltext Access 11 Pages 2018
Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy Fulltext Access 11 Pages 2018
microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression Fulltext Access 11 Pages 2018
Knockdown of MALAT1 enhances chemosensitivity of ovarian cancer cells to cisplatin through inhibiting the Notch1 signaling pathway Fulltext Access 11 Pages 2018
Spatial and temporal translocation of PKCα in single endothelial cell in response to mechanical stimulus Fulltext Access 11 Pages 2018
Prognostic impact of interval breast cancer detection in women with pT1a N0M0 breast cancer with HER2-positive status: Results from a multicentre population-based cancer registry study Fulltext Access 11 Pages 2018
Tumour endothelial marker 1/endosialin-mediated targeting of human sarcoma Fulltext Access 11 Pages 2018
Histamine H4 receptor as a novel therapeutic target for the treatment of Leydig-cell tumours in prepubertal boys Fulltext Access 11 Pages 2018
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial Fulltext Access 11 Pages 2018
Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation Fulltext Access 11 Pages 2018
First-in human, phase 1, dose-escalation pharmacokinetic and pharmacodynamic study of the oral dual PI3K and mTORC1/2 inhibitor PQR309 in patients with advanced solid tumors (SAKK 67/13) Fulltext Access 11 Pages 2018
Treatment strategies and outcomes in diffuse large B-cell lymphoma among 1011 patients aged 75 years or older: A Danish population-based cohort study Fulltext Access 11 Pages 2018
Adjuvant endocrine therapy in premenopausal patients with hormone receptor-positive early breast cancer: Evidence evaluation and GRADE recommendations by the Italian Association of Medical Oncology (AIOM) Fulltext Access 11 Pages 2018
Palbociclib plus endocrine therapy in older women with HR+/HER2- advanced breast cancer: a pooled analysis of randomised PALOMA clinical studies Fulltext Access 11 Pages 2018
Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells Fulltext Access 11 Pages 2018
Glucocorticoids Regulate the Vascular Remodeling of Aortic Dissection Via the p38 MAPK-HSP27 Pathway Mediated by Soluble TNF-RII Fulltext Access 11 Pages 2018
LDL Receptor Gene-ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia With Dominant Inheritance and Diet-induced Coronary Atherosclerosis Fulltext Access 11 Pages 2018
HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles Fulltext Access 11 Pages 2018
Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers Fulltext Access 11 Pages 2018
Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization Fulltext Access 11 Pages 2018
Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy Fulltext Access 11 Pages 2018