NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss Fulltext Access 12 Pages 2006
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells Fulltext Access 12 Pages 2006
Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton Fulltext Access 12 Pages 2006
The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Fulltext Access 12 Pages 2006
Cbfβ-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia Fulltext Access 12 Pages 2006
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis Fulltext Access 12 Pages 2006
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis Fulltext Access 12 Pages 2006
Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations Fulltext Access 12 Pages 2006
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma Fulltext Access 12 Pages 2006
The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans Fulltext Access 12 Pages 2006
Differential promoter usage for insulin-like growth factor-II gene in Chinese hepatocellular carcinoma with hepatitis B virus infection Fulltext Access 12 Pages 2006
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Fulltext Access 12 Pages 2006
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Fulltext Access 12 Pages 2006
Oncogenic MITF dysregulation in clear cell sarcoma: Defining the MiT family of human cancers Fulltext Access 12 Pages 2006
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer Fulltext Access 12 Pages 2006
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature Fulltext Access 12 Pages 2006
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate Fulltext Access 12 Pages 2006
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-κB activation and cell survival Fulltext Access 12 Pages 2006
C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells Fulltext Access 12 Pages 2006
Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation Fulltext Access 12 Pages 2006
A subset of prostate basal cells lacks the expression of corresponding phenotypic markers Fulltext Access 12 Pages 2006
New approaches to identification of antigenic candidates for future prostate cancer immunotherapy Fulltext Access 12 Pages 2006
The Clinical and Biologic Importance of Neovascularization and Angiogenic Signaling Pathways in Chronic Lymphocytic Leukemia Fulltext Access 12 Pages 2006
Neoplastic Meningitis From Systemic Malignancies: Diagnosis, Prognosis and Treatment Fulltext Access 12 Pages 2006
The Hypoxic Inducible Stress Response as a Target for Cancer Drug Discovery Fulltext Access 12 Pages 2006
Thalidomide prevents rat liver cirrhosis via inhibition of oxidative stress Fulltext Access 12 Pages 2006
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations Fulltext Access 12 Pages 2006
Immunohistochemical α- and β-catenin and E-cadherin expression and their clinicopathological significance in human lung adenocarcinoma Fulltext Access 12 Pages 2006
Preparation and in vivo evaluation of a novel stabilized linker for 211At labeling of protein Fulltext Access 12 Pages 2006
CXCR4 Chemokine Receptor Mediates Prostate Tumor Cell Adhesion through α5 and β3 Integrins 1 Fulltext Access 12 Pages 2006
Novel Genes Implicated in Embryonal, Alveolar, and Pleomorphic Rhabdomyosarcoma: A Cytogenetic and Molecular Analysis of Primary Tumors 1 Fulltext Access 12 Pages 2006
Valproic Acid, an Antiepileptic Drug with Histone Deacetylase Inhibitory Activity, Potentiates the Cytotoxic Effect of Apo2L/TRAIL on Cultured Thoracic Cancer Cells through Mitochondria-Dependent Caspase Activation 1 Fulltext Access 12 Pages 2006
Noninvasive Optical Tracking of Red Fluorescent Protein-Expressing Cancer Cells in a Model of Metastatic Breast Cancer Fulltext Access 12 Pages 2006
Overlapping 3q28 amplifications in the COMA cell line and undifferentiated primary sarcoma Fulltext Access 12 Pages 2006
Functional flexibility of Bacillus stearothermophilus formamidopyrimidine DNA-glycosylase Fulltext Access 12 Pages 2006
Advances in prevention and treatment of hepatic disorders following hematopoietic cell transplantation Fulltext Access 12 Pages 2006
Autologous immune strategies to reduce the risk of leukemic relapse: Consideration for IL-15 Fulltext Access 12 Pages 2006
Recent advances in understanding of the DNA double-strand break repair machinery of plants Fulltext Access 12 Pages 2006
Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2 Fulltext Access 12 Pages 2006
Roles of DNA ligase III and XRCC1 in regulating the switch between short patch and long patch BER Fulltext Access 12 Pages 2006
Translesion DNA synthesis across non-DNA segments in cultured human cells Fulltext Access 12 Pages 2006
Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity Fulltext Access 12 Pages 2006
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance Fulltext Access 12 Pages 2006
Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability Fulltext Access 12 Pages 2006
MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants Fulltext Access 12 Pages 2006
MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides Fulltext Access 12 Pages 2006
Closely opposed apurinic/apyrimidinic sites are converted to double strand breaks in Escherichia coli even in the absence of exonuclease III, endonuclease IV, nucleotide excision repair and AP lyase cleavage Fulltext Access 12 Pages 2006
Specific amino acid residues in the β sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli Fulltext Access 12 Pages 2006
Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations Fulltext Access 12 Pages 2006
Transpositions and translocations induced by site-specific double-strand breaks in budding yeast Fulltext Access 12 Pages 2006
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Fulltext Access 12 Pages 2006
Nonmyeloablative Stem Cell Transplantation Is an Effective Therapy for Refractory or Relapsed Hodgkin Lymphoma: Results of a Spanish Prospective Cooperative Protocol Fulltext Access 12 Pages 2006
Impaired Allogeneic Activation and T-helper 1 Differentiation of Human Cord Blood Naive CD4 T Cells Fulltext Access 12 Pages 2006
The immunophenotype of acute myeloid leukemia: is there a relationship with prognosis? Fulltext Access 12 Pages 2006
Toward Biomarkers for Chronic Graft-versus-Host Disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: III. Biomarker Working Group Report Fulltext Access 12 Pages 2006
Reduced Incidence of Acute and Chronic Graft-versus-Host Disease with the Addition of Thymoglobulin to a Targeted Busulfan/Cyclophosphamide Regimen Fulltext Access 12 Pages 2006
Immune Tolerance to Self-Major Histocompatability Complex Class II Antigens after Bone Marrow Transplantation: Role of Regulatory T Cells Fulltext Access 12 Pages 2006
Unmanipulated HLA 2–3 Antigen-Mismatched (Haploidentical) Stem Cell Transplantation Using Nonmyeloablative Conditioning Fulltext Access 12 Pages 2006
Impact of Donor and Recipient Sex and Parity on Outcomes of HLA-Identical Sibling Allogeneic Hematopoietic Stem Cell Transplantation Fulltext Access 12 Pages 2006
Symposium Summary Fourth Annual International Umbilical Cord Blood Transplantation Symposium, Los Angeles, California, May 19-20, 2006 Fulltext Access 12 Pages 2006
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia Fulltext Access 12 Pages 2006
Unrelated Donor Status and High Donor Age Independently Affect Immunologic Recovery after Nonmyeloablative Conditioning Fulltext Access 12 Pages 2006
Expression of Chemokines in GVHD Target Organs Is Influenced by Conditioning and Genetic Factors and Amplified by GVHR Fulltext Access 12 Pages 2006
Unrelated Donor Granulocyte Colony-Stimulating Factor–Mobilized Peripheral Blood Mononuclear Cell Transplantation after Nonmyeloablative Conditioning: The Effect of Postgrafting Mycophenolate Mofetil Dosing Fulltext Access 12 Pages 2006
Emerging applications for phospho-proteomics in cancer molecular therapeutics Fulltext Access 12 Pages 2006
Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner Fulltext Access 12 Pages 2006
Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling Fulltext Access 12 Pages 2006
BRCA1—A good predictive marker of drug sensitivity in breast cancer treatment? Fulltext Access 12 Pages 2006
Preclinical and Clinical Development of Novel Agents That Target the Protein Kinase C Family Fulltext Access 13 Pages 2006
Tubulin-Associated Drug Targets: Aurora Kinases, Polo-like Kinases, and Others Fulltext Access 13 Pages 2006
Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth Fulltext Access 13 Pages 2006
Prostate Tumor Growth and Recurrence Can Be Modulated by the ω-6:ω-3 Ratio in Diet: Athymic Mouse Xenograft Model Simulating Radical Prostatectomy 1 Fulltext Access 13 Pages 2006
Conditional Expression of Human 15-Lipoxygenase-1 in Mouse Prostate Induces Prostatic Intraepithelial Neoplasia: The FLiMP Mouse Model 1 Fulltext Access 13 Pages 2006
SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection 1 Fulltext Access 13 Pages 2006
Children's exposure to environmental pollutants and biomarkers of genetic damage: I. Overview and critical issues Fulltext Access 13 Pages 2006
Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine Fulltext Access 13 Pages 2006
Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies Fulltext Access 13 Pages 2006