In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or -2 Fulltext Access 12 Pages 2006
Non-random distribution of instability-associated chromosomal rearrangement breakpoints in human lymphoblastoid cells Fulltext Access 12 Pages 2006
Environmental and nutritional effects on the epigenetic regulation of genes Fulltext Access 12 Pages 2006
Influence of DNA repair gene polymorphisms of hOGG1, XRCC1, XRCC3, ERCC2 and the folate metabolism gene MTHFR on chromosomal aberration frequencies Fulltext Access 12 Pages 2006
Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay Fulltext Access 12 Pages 2006
Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate α11 integrin chain expression in mesenchymal cells Fulltext Access 12 Pages 2006
Differential cell adhesion to vocal fold extracellular matrix constituents Fulltext Access 12 Pages 2006
Both direct and collagen-mediated signals are required for active vitamin D3-elicited differentiation of human osteoblastic cells: Roles of osterix, an osteoblast-related transcription factor Fulltext Access 12 Pages 2006
Effects of covalently attached chondroitin sulfate on aggrecan cleavage by ADAMTS-4 and MMP-13 Fulltext Access 12 Pages 2006
The N-terminal 70-kDa fragment of fibronectin binds to cell surface fibronectin assembly sites in the absence of intact fibronectin Fulltext Access 12 Pages 2006
Clinicopathologic features and prognostic implications of epidermal growth factor receptor (EGFR) gene copy number and protein expression in non-small cell lung cancer Fulltext Access 12 Pages 2006
Intratumoral administration of cisplatin through a bronchoscope followed by irradiation for treatment of inoperable non-small cell obstructive lung cancer Fulltext Access 12 Pages 2006
Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer Fulltext Access 12 Pages 2006
Formamidopyrimidine adducts are detected using the comet assay in human cells treated with reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Fulltext Access 12 Pages 2006
A Fas agonist induces high levels of apoptosis in haematological malignancies Fulltext Access 12 Pages 2006
Depsipeptide-resistant KU812 cells show reversible P-glycoprotein expression, hyper-acetylated histones, and modulated gene expression profile Fulltext Access 12 Pages 2006
The chemosensitivity to therapy of childhood early B acute lymphoblastic leukemia could be determined by the combined expression of CD34, SPI-B and BCR genes Fulltext Access 12 Pages 2006
Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines Fulltext Access 12 Pages 2006
Inhibitory effect of 8-oxo-7,8-dihydro-2′-deoxyguanosine on the growth of KG-1 myelosarcoma in Balb/c nude mice Fulltext Access 12 Pages 2006
CXCR4 and CCR5 mediate homing of primitive bone marrow–derived hematopoietic cells to the postnatal thymus Fulltext Access 12 Pages 2006
Identification of HLA-A33-restricted CMV pp65 epitopes as common targets for CD8+ CMV-specific cytotoxic T lymphocytes Fulltext Access 12 Pages 2006
Human herpesvirus 6 impairs differentiation of monocytes to dendritic cells Fulltext Access 12 Pages 2006
Leukemia-stimulated bone marrow endothelium promotes leukemia cell survival Fulltext Access 12 Pages 2006
Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1 Fulltext Access 12 Pages 2006
Early appearance of stem/progenitor cells with neural-like characteristics in human cord blood mononuclear fraction cultured in vitro Fulltext Access 12 Pages 2006
Application of public-domain statistical analysis software for evaluation and comparison of comet assay data Fulltext Access 12 Pages 2006
Antigenotoxic effects of three essential oils in diploid yeast (Saccharomyces cerevisiae) after treatments with UVC radiation, 8-MOP plus UVA and MMS Fulltext Access 12 Pages 2006
iMARS—Mutation analysis reporting software: An analysis of spontaneous cII mutation spectra Fulltext Access 12 Pages 2006
The role of steric effects in the direct mutagenicity of N-acyloxy-N-alkoxyamides Fulltext Access 12 Pages 2006
Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes Fulltext Access 12 Pages 2006
Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats Fulltext Access 12 Pages 2006
Role of nucleotide excision repair deficiency in intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice Fulltext Access 12 Pages 2006
A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp. (honeybush) and Camellia sinensis teas Fulltext Access 12 Pages 2006
Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair Fulltext Access 12 Pages 2006
Bystander-mediated genomic instability after high LET radiation in murine primary haemopoietic stem cells Fulltext Access 12 Pages 2006
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces Phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver Fulltext Access 12 Pages 2006
Granulocyte colony-stimulating factor enhances the in vitro cytotoxicity of gemtuzumab ozogamicin against acute myeloid leukemia cell lines and primary blast cells Fulltext Access 12 Pages 2006
Molecular mechanisms for maintenance of G-rich short tandem repeats capable of adopting G4 DNA structures Fulltext Access 12 Pages 2006
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid Fulltext Access 12 Pages 2006
Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci Fulltext Access 12 Pages 2006
Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) Fulltext Access 12 Pages 2006
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae Fulltext Access 12 Pages 2006
Efficient repair of bleomycin-induced double-strand breaks in barley ribosomal genes Fulltext Access 12 Pages 2006
Can individual repair kinetics of UVC-induced DNA damage in human lymphocytes be assessed through the comet assay? Fulltext Access 12 Pages 2006
Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair Fulltext Access 12 Pages 2006
Pir51, a Rad51-interacting protein with high expression in aggressive lymphoma, controls mitomycin C sensitivity and prevents chromosomal breaks Fulltext Access 12 Pages 2006
Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation Fulltext Access 12 Pages 2006
Comparative investigations of sodium arsenite, arsenic trioxide and cadmium sulphate in combination with gamma-radiation on apoptosis, micronuclei induction and DNA damage in a human lymphoblastoid cell line Fulltext Access 12 Pages 2006
Proteomic analysis of ursolic acid-induced apoptosis in cervical carcinoma cells Fulltext Access 12 Pages 2006
Chemosensitization of bladder cancer cells by survivin-directed antisense oligodeoxynucleotides and siRNA Fulltext Access 12 Pages 2006
Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases Fulltext Access 12 Pages 2006
Transfection of mouse macrophage metalloelastase gene into murine CT-26 colon cancer cells suppresses orthotopic tumor growth, angiogenesis and vascular endothelial growth factor expression Fulltext Access 12 Pages 2006
FTY720, a fungus metabolite, inhibits invasion ability of androgen-independent prostate cancer cells through inactivation of RhoA-GTPase Fulltext Access 12 Pages 2006
Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2 Fulltext Access 12 Pages 2006
Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis Fulltext Access 12 Pages 2006
SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines Fulltext Access 12 Pages 2006
Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells Fulltext Access 12 Pages 2006
Selenium- or quercetin-induced retardation of DNA synthesis in primary prostate cells occurs in the presence of a concomitant reduction in androgen-receptor activity Fulltext Access 12 Pages 2006
Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line Fulltext Access 12 Pages 2006
Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases Fulltext Access 12 Pages 2006
Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis Fulltext Access 12 Pages 2006
Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore Fulltext Access 12 Pages 2006
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes Fulltext Access 12 Pages 2006
Localization of a mutant p53 response element on the Tissue Inhibitor of Metalloproteinase-3 promoter: Mutant p53 activities are distinct from wild-type Fulltext Access 12 Pages 2006
Prognostic significance of p53 mutation in suboptimally resected advanced ovarian carcinoma treated with the combination chemotherapy of paclitaxel and carboplatin Fulltext Access 12 Pages 2006
Tumor quantification of several fluoropyrimidines resistance gene expression with a unique quantitative RT-PCR method. Implications for pretherapeutic determination of tumor resistance phenotype Fulltext Access 12 Pages 2006
Relative and absolute risk of colorectal cancer for individuals with a family history: A meta-analysis Fulltext Access 12 Pages 2006
Efficient gene transfer into hematopoietic cells by a retargeting adenoviral vector system with a chimeric fiber of adenovirus serotype 5 and 11p Fulltext Access 12 Pages 2006
Stromal cell lines from the aorta-gonado-mesonephros region are potent supporters of murine and human hematopoiesis Fulltext Access 12 Pages 2006
Bone marrow production of lung cells: The impact of G-CSF, cardiotoxin, graded doses of irradiation, and subpopulation phenotype Fulltext Access 12 Pages 2006
Cellular foundation of curcumin-induced apoptosis in follicular lymphoma cell lines Fulltext Access 12 Pages 2006
Chemoattractants, extracellular proteases, and the integrated host defense response Fulltext Access 12 Pages 2006
Hematopoietic chimerism induces renal and skin allograft tolerance in DLA-identical dogs Fulltext Access 12 Pages 2006
Lenticular chaperones suppress the aggregation of the cataract-causing mutant T5P γC-crystallin Fulltext Access 12 Pages 2006
Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway Fulltext Access 12 Pages 2006
Metabolic regulation of neutrophil spreading, membrane tubulovesicular extensions (cytonemes) formation and intracellular pH upon adhesion to fibronectin Fulltext Access 12 Pages 2006
Evidence for serpinB2-independent protection from TNF-α-induced apoptosis Fulltext Access 12 Pages 2006
Intracellular localization and concentration as well as photodynamic effects of benzoporphyrin derivative monoacid ring A in four types of rodent tumor cells Fulltext Access 12 Pages 2006
Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development Fulltext Access 12 Pages 2006
Bone tumours in European children and adolescents, 1978–1997. Report from the Automated Childhood Cancer Information System project Fulltext Access 12 Pages 2006
Malignant renal tumours incidence and survival in European children (1978–1997): Report from the Automated Childhood Cancer Information System project Fulltext Access 12 Pages 2006
Evidence-based treatment of metastatic breast cancer – 2006 recommendations by the AGO Breast Commission Fulltext Access 12 Pages 2006
DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity Fulltext Access 12 Pages 2006
Literature Highlights: Recent research in infectious disease drug resistance Fulltext Access 12 Pages 2006
Human endogenous retrovirus HERV-H family in human tissues and cancer cells: expression, identification, and phylogeny Fulltext Access 12 Pages 2006
Low-frequency common fragile sites: Link to neuropsychiatric disorders? Fulltext Access 12 Pages 2006