Functional and Structural Characterization of Spl Proteases from Staphylococcus aureus Fulltext Access 10 Pages 2006
Crystal Structure of Thermus aquaticus Gfh1, a Gre-factor Paralog that Inhibits rather than Stimulates Transcript Cleavage Fulltext Access 10 Pages 2006
Insights on a New PDI-like Family: Structural and Functional Analysis of a Protein Disulfide Oxidoreductase from the Bacterium Aquifex aeolicus Fulltext Access 10 Pages 2006
Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins Fulltext Access 10 Pages 2006
High-resolution Crystal Structure of a Truncated ColE7 Translocation Domain: Implications for Colicin Transport Across Membranes Fulltext Access 10 Pages 2006
Crystal Structure of Yeast Peroxisomal Multifunctional Enzyme: Structural Basis for Substrate Specificity of (3R)-hydroxyacyl-CoA Dehydrogenase Units Fulltext Access 10 Pages 2006
Shape of the Free Energy Barriers for Protein Folding Probed by Multiple Perturbation Analysis Fulltext Access 10 Pages 2006
Crystal Structures of an Enantioselective Fab-fragment in Free and Complex Forms Fulltext Access 10 Pages 2006
Structural Basis of the Suppressed Catalytic Activity of Wild-type Human Glutathione Transferase T1-1 Compared to its W234R Mutant Fulltext Access 10 Pages 2006
A Trans-dominant Negative 37 kDa/67 kDa Laminin Receptor Mutant Impairs PrPSc Propagation in Scrapie-infected Neuronal Cells Fulltext Access 10 Pages 2006
Analysis of Interactions Between Mismatch Repair Initiation Factors and the Replication Processivity Factor PCNA Fulltext Access 10 Pages 2006
Effects of Ser16 Phosphorylation on the Allosteric Transitions of Phospholamban/Ca2+-ATPase Complex Fulltext Access 10 Pages 2006
Rapid Synthesis of a Register-specific Heterotrimeric Type I Collagen Helix Encompassing the Integrin α2β1 Binding Site Fulltext Access 10 Pages 2006
The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies Fulltext Access 10 Pages 2006
Conformational and Quantitative Characterization of Oritavancin–Peptidoglycan Complexes in Whole Cells of Staphylococcus aureus by in Vivo13C and 15N Labeling Fulltext Access 10 Pages 2006
Crystal Structure and Functional Studies Reveal that PAS Factor from Vibrio vulnificus is a Novel Member of the Saposin-fold Family Fulltext Access 10 Pages 2006
Structure and Catalytic Properties of an Engineered Heterodimer of Enolase Composed of One Active and One Inactive Subunit Fulltext Access 10 Pages 2006
Identification of a furA cis Antisense RNA in the Cyanobacterium Anabaena sp. PCC 7120 Fulltext Access 10 Pages 2006
Cooperative Effects of Cofilin (ADF) on Actin Structure Suggest Allosteric Mechanism of Cofilin Function Fulltext Access 10 Pages 2006
Location of Trp265 in Metarhodopsin II: Implications for the Activation Mechanism of the Visual Receptor Rhodopsin Fulltext Access 10 Pages 2006
Sea Urchin Arylsulfatase Insulator Exerts its Anti-silencing Effect without Interacting with the Nuclear Matrix Fulltext Access 10 Pages 2006
Xin-repeats and Nebulin-like Repeats Bind to F-actin in a Similar Manner Fulltext Access 10 Pages 2006
Human Jagged 1 Mutants Cause Liver Defect in Alagille Syndrome by Overexpression of Hepatocyte Growth Factor Fulltext Access 10 Pages 2006
The Structure of Formylmethanofuran: Tetrahydromethanopterin Formyltransferase in Complex with its Coenzymes Fulltext Access 10 Pages 2006
K644E/M FGFR3 Mutants Activate Erk1/2 from the Endoplasmic Reticulum through FRS2α and PLCγ-independent Pathways Fulltext Access 10 Pages 2006
An Isoform of GTPase Regulator DOCK4 Localizes to the Stereocilia in the Inner Ear and Binds to Harmonin (USH1C) Fulltext Access 10 Pages 2006
Probing Intercellular Interactions between Vascular Endothelial Cadherin Pairs at Single-molecule Resolution and in Living Cells Fulltext Access 10 Pages 2006
Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM Fulltext Access 10 Pages 2006
Solution Scattering Reveals Large Differences in the Global Structures of Type II Protein Kinase A Isoforms Fulltext Access 10 Pages 2006
Common Motifs and Topological Effects in the Protein Folding Transition State Fulltext Access 11 Pages 2006
Seeding-dependent Propagation and Maturation of β2-Microglobulin Amyloid Fibrils Under High Pressure Fulltext Access 11 Pages 2006
Membrane-transferring Sequences of the HIV-1 Gp41 Ectodomain Assemble into an Immunogenic Complex Fulltext Access 11 Pages 2006
A Large Domain Swap in the VirB11 ATPase of Brucella suis Leaves the Hexameric Assembly Intact Fulltext Access 11 Pages 2006
Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases Fulltext Access 11 Pages 2006
Microsecond Dynamics of Protein–DNA Interactions: Direct Observation of the Wrapping/Unwrapping Kinetics of Single-stranded DNA around the E. coli SSB Tetramer Fulltext Access 11 Pages 2006
Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase Fulltext Access 11 Pages 2006
Crystal Structure of Neoculin: Insights into its Sweetness and Taste-modifying Activity Fulltext Access 11 Pages 2006
Sterol Regulatory Element-binding Protein-2 Negatively Regulates Low Density Lipoprotein Receptor-related Protein Transcription Fulltext Access 11 Pages 2006
The Crystal Structure of Mouse Nup35 Reveals Atypical RNP Motifs and Novel Homodimerization of the RRM Domain Fulltext Access 11 Pages 2006
Structural Differences in Aβ Amyloid Protofibrils and Fibrils Mapped by Hydrogen Exchange – Mass Spectrometry with On-line Proteolytic Fragmentation Fulltext Access 11 Pages 2006
From Monomeric to Homodimeric Endonucleases and Back: Engineering Novel Specificity of LAGLIDADG Enzymes Fulltext Access 11 Pages 2006
Structure-based Stability Engineering of the Mouse IgG1 Fab Fragment by Modifying Constant Domains Fulltext Access 11 Pages 2006
Chimeric Fc Receptors Identify Ligand Binding Regions in Human Glycoprotein VI Fulltext Access 11 Pages 2006
Identification of Two Interaction Sites in SecY that Are Important for the Functional Interaction with SecA Fulltext Access 11 Pages 2006
Chain Length-dependent Binding of Fatty Acid Anions to Human Serum Albumin Studied by Site-directed Mutagenesis Fulltext Access 11 Pages 2006
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP Fulltext Access 11 Pages 2006
Crucial Steps in the Structure Determination of the Na+/H+ Antiporter NhaA in its Native Conformation Fulltext Access 11 Pages 2006
Crystal Structure of a Multi-domain Immunophilin from Arabidopsis thaliana: A Paradigm for Regulation of Plant ABC Transporters Fulltext Access 11 Pages 2006
Thermus thermophilus Bacteriophage ϕYS40 Genome and Proteomic Characterization of Virions Fulltext Access 11 Pages 2006
Energetics and Kinetics of Cooperative Cofilin–Actin Filament Interactions Fulltext Access 11 Pages 2006
Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS Fulltext Access 11 Pages 2006
Structure of the Bet3–Tpc6B Core of TRAPP: Two Tpc6 Paralogs Form Trimeric Complexes with Bet3 and Mum2 Fulltext Access 11 Pages 2006
Expression of Connexin47 in Oligodendrocytes is Regulated by the Sox10 Transcription Factor Fulltext Access 11 Pages 2006
Osmolyte Trimethylamine N-Oxide Converts Recombinant α-Helical Prion Protein to its Soluble β-Structured Form at High Temperature Fulltext Access 11 Pages 2006
The Crystal Structure of an ADP Complex of Bacillus subtilis Pyridoxal Kinase Provides Evidence for the Parallel Emergence of Enzyme Activity During Evolution Fulltext Access 11 Pages 2006
Point Mutations in Protein Globular Domains: Contributions from Function, Stability and Misfolding Fulltext Access 11 Pages 2006
Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae Fulltext Access 11 Pages 2006
Two Parts of the T3S4 Domain of the Hook-length Control Protein FliK Are Essential for the Substrate Specificity Switching of the Flagellar Type III Export Apparatus Fulltext Access 11 Pages 2006
Localization of Prefoldin Interaction Sites in the Hyperthermophilic Group II Chaperonin and Correlations between Binding Rate and Protein Transfer Rate Fulltext Access 11 Pages 2006
Structure of a Hyper-cleavable Monomeric Fragment of Phage λ Repressor Containing the Cleavage Site Region Fulltext Access 11 Pages 2006
The 2.1 Å Crystal Structure of copGFP, a Representative Member of the Copepod Clade Within the Green Fluorescent Protein Superfamily Fulltext Access 11 Pages 2006
The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein Fulltext Access 11 Pages 2006
Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism Fulltext Access 11 Pages 2006
Recognition and Positioning of mRNA in the Ribosome by tRNAs with Expanded Anticodons Fulltext Access 11 Pages 2006
Asp302 Determines Potassium Dependence of a RadA Recombinase from Methanococcus voltae Fulltext Access 11 Pages 2006
The Crystal Structure of the Transthyretin-like Protein from Salmonella dublin, a Prokaryote 5-Hydroxyisourate Hydrolase Fulltext Access 11 Pages 2006
Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis Fulltext Access 11 Pages 2006
Hydrogen Bonding Markedly Reduces the pK of Buried Carboxyl Groups in Proteins Fulltext Access 11 Pages 2006
Direct Observation of Oligomeric Species formed in the Early Stages of Amyloid Fibril Formation using Electrospray Ionisation Mass Spectrometry Fulltext Access 11 Pages 2006
Opening of Holes in Liposomal Membranes Is Induced by Proteins Possessing the FERM Domain Fulltext Access 11 Pages 2006
Rapid Kinetics of Protein–Nucleic Acid Interaction is a Major Component of HIV-1 Nucleocapsid Protein’s Nucleic Acid Chaperone Function Fulltext Access 11 Pages 2006
The Evolution of Catalytic Efficiency and Substrate Promiscuity in Human Theta Class 1-1 Glutathione Transferase Fulltext Access 11 Pages 2006
Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer Fulltext Access 11 Pages 2006
A Mutation in the S-switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for CBFβ Regulation Fulltext Access 11 Pages 2006
A Conserved Base-pair between tRNA and 23 S rRNA in the Peptidyl Transferase Center Is Important for Peptide Release Fulltext Access 11 Pages 2006
Physical and Functional Interactions between the Prostate Suppressor Homeoprotein NKX3.1 and Serum Response Factor Fulltext Access 11 Pages 2006
The UAA/GAN Internal Loop Motif: A New RNA Structural Element that Forms a Cross-strand AAA Stack and Long-range Tertiary Interactions Fulltext Access 11 Pages 2006
Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis Fulltext Access 11 Pages 2006
Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation Fulltext Access 11 Pages 2006