Characterization of Dual Substrate Binding Sites in the Homodimeric Structure of Escherichia coli mRNA Interferase MazF Fulltext Access 12 Pages 2006
Characterization of the DNA Binding Features of Saccharomyces castellii Cdc13p Fulltext Access 12 Pages 2006
Effect of Hsp70 Chaperone on the Folding and Misfolding of Polypeptides Modeling an Elongating Protein Chain Fulltext Access 12 Pages 2006
d-3-Hydroxybutyrate Dehydrogenase from Pseudomonas fragi: Molecular Cloning of the Enzyme Gene and Crystal Structure of the Enzyme Fulltext Access 12 Pages 2006
Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion Fulltext Access 12 Pages 2006
GTP-dependent Formation of a Ribonucleoprotein Subcomplex Required for Ribosome Biogenesis Fulltext Access 12 Pages 2006
Cis and Trans-acting Effects on a Mutational Hotspot Involving a Replication Template Switch Fulltext Access 12 Pages 2006
Recognition of Oxidatively Modified Bases within the Biotin-binding Site of Avidin Fulltext Access 12 Pages 2006
The 1.6 Å X-ray Structure of the Unusual c-type Cytochrome, Cytochrome cL, from the Methylotrophic Bacterium Methylobacterium extorquens Fulltext Access 12 Pages 2006
Kinetic Studies of Folding of the B-domain of Staphylococcal Protein A with Molecular Dynamics and a United-residue (UNRES) Model of Polypeptide Chains Fulltext Access 12 Pages 2006
Early Effects of Topoisomerase I Inhibition on RNA Polymerase II Along Transcribed Genes in Human Cells Fulltext Access 12 Pages 2006
Model for RNA Binding and the Catalytic Site of the RNase Kid of the Bacterial parD Toxin–Antitoxin System Fulltext Access 12 Pages 2006
R-state Haemoglobin with Low Oxygen Affinity: Crystal Structures of Deoxy Human and Carbonmonoxy Horse Haemoglobin Bound to the Effector Molecule L35 Fulltext Access 12 Pages 2006
Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies Fulltext Access 12 Pages 2006
Amyloid-β Peptide Disruption of Lipid Membranes and the Effect of Metal Ions Fulltext Access 12 Pages 2006
Alanine Scanning of MS2 Coat Protein Reveals Protein–Phosphate Contacts Involved in Thermodynamic Hot Spots Fulltext Access 12 Pages 2006
Time-resolved Small-angle X-ray Scattering Investigation of the Folding Dynamics of Heme Oxygenase: Implication of the Scaling Relationship for the Submillisecond Intermediates of Protein Folding Fulltext Access 12 Pages 2006
Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1) Fulltext Access 12 Pages 2006
A Novel-type Substrate-selectivity Filter and ER-exit Determinants in the UapA Purine Transporter Fulltext Access 12 Pages 2006
A Pathway for the Transmission of Allosteric Signals in the Ribosome through a Network of RNA Tertiary Interactions Fulltext Access 12 Pages 2006
NMDA receptors mediate calcium-dependent, bidirectional changes in dendritic PICK1 clustering Fulltext Access 12 Pages 2006
Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system Fulltext Access 12 Pages 2006
The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1 Fulltext Access 12 Pages 2006
Network stability through homeostatic scaling of excitatory and inhibitory synapses following inactivity in CA3 of rat organotypic hippocampal slice cultures Fulltext Access 12 Pages 2006
A regulated switch of chick neurofascin isoforms modulates ligand recognition and neurite extension Fulltext Access 12 Pages 2006
Defective neuromuscular synaptogenesis in mice expressing constitutively active ErbB2 in skeletal muscle fibers Fulltext Access 12 Pages 2006
A novel role of circadian transcription factor DBP in hippocampal plasticity Fulltext Access 12 Pages 2006
Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion Fulltext Access 12 Pages 2006
Glial conversion of SVZ-derived committed neuronal precursors after ectopic grafting into the adult brain Fulltext Access 12 Pages 2006
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses Fulltext Access 12 Pages 2006
Site-specific dephosphorylation of doublecortin (DCX) by protein phosphatase 1 (PP1) Fulltext Access 12 Pages 2006
Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient Fulltext Access 12 Pages 2006
Activation of N-methyl-d-aspartate receptor induces a shift of drebrin distribution: Disappearance from dendritic spines and appearance in dendritic shafts Fulltext Access 12 Pages 2006
Activity-dependent scaling of GABAergic synapse strength is regulated by brain-derived neurotrophic factor Fulltext Access 12 Pages 2006
Increased myelinating capacity of embryonic stem cell derived oligodendrocyte precursors after treatment by interleukin-6/soluble interleukin-6 receptor fusion protein Fulltext Access 12 Pages 2006
The Drosophila microtubule associated protein Futsch is phosphorylated by Shaggy/Zeste-white 3 at an homologous GSK3β phosphorylation site in MAP1B Fulltext Access 12 Pages 2006
Expression of classical cadherins in the cerebellar anlage: Quantitative and functional aspects Fulltext Access 12 Pages 2006
Increased expression of the β4 and α5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines IL-6 or IFN-α in the central nervous system Fulltext Access 12 Pages 2006
Netrin1 exerts a chemorepulsive effect on migrating cerebellar interneurons in a Dcc-independent way Fulltext Access 12 Pages 2006
Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3β and a caspase-9-dependent apoptosis in cerebellar granule neurons Fulltext Access 12 Pages 2006
Dendritic arbors of developing retinal ganglion cells are stabilized by β1-integrins Fulltext Access 12 Pages 2006
Conditional labeling of newborn granule cells to visualize their integration into established circuits in hippocampal slice cultures Fulltext Access 12 Pages 2006
Cryo-electron Microscopy Reveals Conserved and Divergent Features of Gag Packing in Immature Particles of Rous Sarcoma Virus and Human Immunodeficiency Virus Fulltext Access 12 Pages 2006
Mapping a Neutralizing Epitope on the SARS Coronavirus Spike Protein: Computational Prediction Based on Affinity-selected Peptides Fulltext Access 12 Pages 2006
Local Kinetic Measures of Macromolecular Structure Reveal Partitioning among Multiple Parallel Pathways from the Earliest Steps in the Folding of a Large RNA Molecule Fulltext Access 12 Pages 2006
The Type III Flagellar Export Specificity Switch is Dependent on FliK Ruler and a Molecular Clock Fulltext Access 12 Pages 2006
Viscous Drag as the Source of Active Site Perturbation during Protease Translocation: Insights into how Inhibitory Processes are Controlled by Serpin Metastability Fulltext Access 12 Pages 2006
Do Proteins with Similar Folds Have Similar Transition State Structures? A Diffuse Transition State of the 169 Residue Apoflavodoxin Fulltext Access 12 Pages 2006
The Importance of RNA Structure in RNA Editing and a Potential Proofreading Mechanism for Correct Guide RNA:pre-mRNA Binary Complex Formation Fulltext Access 12 Pages 2006
Structure of the Neuronal Protein Calexcitin Suggests a Mode of Interaction in Signalling Pathways of Learning and Memory Fulltext Access 12 Pages 2006
Multiple Solvent Crystal Structures: Probing Binding Sites, Plasticity and Hydration Fulltext Access 12 Pages 2006
Binding Properties of Pyochelin and Structurally Related Molecules to FptA of Pseudomonas aeruginosa Fulltext Access 12 Pages 2006
Entropically Driven MHC Class I Recognition by Human Inhibitory Receptor Leukocyte Ig-like Receptor B1 (LILRB1/ILT2/CD85j) Fulltext Access 12 Pages 2006
The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor Fulltext Access 12 Pages 2006
Role of E. coli NusA in Phage HK022 Nun-mediated Transcription Termination Fulltext Access 12 Pages 2006
Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase Fulltext Access 12 Pages 2006
Self-association of the Transmembrane Domain of an Anthrax Toxin Receptor Fulltext Access 12 Pages 2006
The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for β-Catenin Fulltext Access 12 Pages 2006
Molecular Dynamics Simulations of the Tetracycline-repressor Protein: The Mechanism of Induction Fulltext Access 12 Pages 2006
Domain Organization and Crystal Structure of the Catalytic Domain of E. coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA Fulltext Access 12 Pages 2006
Calcium-dependent Tetramer Formation of S100A8 and S100A9 is Essential for Biological Activity Fulltext Access 12 Pages 2006
Structural Basis for Substrate Recognition by the Editing Domain of Isoleucyl-tRNA Synthetase Fulltext Access 12 Pages 2006
The N-terminal Half of the Peroxisomal Cycling Receptor Pex5p is a Natively Unfolded Domain Fulltext Access 12 Pages 2006
Visualization of the Annealing of Complementary Single-stranded DNA Catalyzed by the Herpes Simplex Virus Type 1 ICP8 SSB/Recombinase Fulltext Access 12 Pages 2006
Efficient Prediction of Nucleic Acid Binding Function from Low-resolution Protein Structures Fulltext Access 12 Pages 2006
Reconstitution of Calmodulin from Domains and Subdomains: Influence of Target Peptide Fulltext Access 12 Pages 2006
The Crystal Structure of the Apoenzyme of the Iron–Sulphur Cluster-free Hydrogenase Fulltext Access 12 Pages 2006
Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen Fulltext Access 12 Pages 2006
Filling Small, Empty Protein Cavities: Structural and Energetic Consequences Fulltext Access 12 Pages 2006
Bacillus subtilis Bacteriophage SPP1 G40P Helicase Lacking the N-terminal Domain Unwinds DNA Bidirectionally Fulltext Access 12 Pages 2006
High-resolution Crystal Structure of Aldose Reductase Complexed with the Novel Sulfonyl-pyridazinone Inhibitor Exhibiting an Alternative Active Site Anchoring Group Fulltext Access 12 Pages 2006
The Crystal Structure of Polyhydroxybutyrate Depolymerase from Penicillium funiculosum Provides Insights into the Recognition and Degradation of Biopolyesters Fulltext Access 12 Pages 2006
Structure and Substrate Recognition of the Escherichia coli DNA Adenine Methyltransferase Fulltext Access 12 Pages 2006
Crystal Structure of a Novel Viral Protease with a Serine/Lysine Catalytic Dyad Mechanism Fulltext Access 12 Pages 2006
Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.) Fulltext Access 12 Pages 2006
Artemis Phosphorylated by DNA-dependent Protein Kinase Associates Preferentially with Discrete Regions of Chromatin Fulltext Access 12 Pages 2006
Nanopore–Protein Interactions Dramatically Alter Stability and Yield of the Native State in Restricted Spaces Fulltext Access 12 Pages 2006
Structure of the α-Actinin–Vinculin Head Domain Complex Determined by Cryo-electron Microscopy Fulltext Access 12 Pages 2006
Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide Fulltext Access 12 Pages 2006
Structural Basis of the Nucleotide Driven Conformational Changes in the AAA+ Domain of Transcription Activator PspF Fulltext Access 12 Pages 2006
Concordant Exploration of the Kinetics of RNA Folding from Global and Local Perspectives Fulltext Access 12 Pages 2006
Structure of the Escherichia coli Quorum Sensing Protein SdiA: Activation of the Folding Switch by Acyl Homoserine Lactones Fulltext Access 12 Pages 2006