Proline Isomerization of Histone H3 Regulates Lysine Methylation and Gene Expression Fulltext Access 12 Pages 2006
Cyclin-Dependent Kinase Directly Regulates Initiation of Meiotic Recombination Fulltext Access 12 Pages 2006
Live-Cell Imaging Reveals Replication of Individual Replicons in Eukaryotic Replication Factories Fulltext Access 12 Pages 2006
Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates Fulltext Access 12 Pages 2006
Structural Insights into RNA-Dependent Ring Closure and ATPase Activation by the Rho Termination Factor Fulltext Access 12 Pages 2006
The HAMP Domain Structure Implies Helix Rotation in Transmembrane Signaling Fulltext Access 12 Pages 2006
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases Fulltext Access 12 Pages 2006
Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III Fulltext Access 12 Pages 2006
Yersinia Virulence Depends on Mimicry of Host Rho-Family Nucleotide Dissociation Inhibitors Fulltext Access 12 Pages 2006
Postnatal Deletion of Numb/Numblike Reveals Repair and Remodeling Capacity in the Subventricular Neurogenic Niche Fulltext Access 12 Pages 2006
The Fly CAMTA Transcription Factor Potentiates Deactivation of Rhodopsin, a G Protein-Coupled Light Receptor Fulltext Access 12 Pages 2006
The DNA Damage Machinery and Homologous Recombination Pathway Act Consecutively to Protect Human Telomeres Fulltext Access 12 Pages 2006
RORα-Mediated Purkinje Cell Development Determines Disease Severity in Adult SCA1 Mice Fulltext Access 12 Pages 2006
Activation of Glucosidase via Stress-Induced Polymerization Rapidly Increases Active Pools of Abscisic Acid Fulltext Access 12 Pages 2006
Making or Breaking the Heart: From Lineage Determination to Morphogenesis Fulltext Access 12 Pages 2006
Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas Fulltext Access 12 Pages 2006
DEMETER DNA Glycosylase Establishes MEDEA Polycomb Gene Self-Imprinting by Allele-Specific Demethylation Fulltext Access 12 Pages 2006
Molecular nature of methicillin-resistant Staphylococcus aureus derived from explosive nosocomial outbreaks of the 1980s in Japan Fulltext Access 12 Pages 2006
Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia Fulltext Access 12 Pages 2006
Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine α-amidating monooxygenase (PAM) Fulltext Access 12 Pages 2006
The molecular basis of multidrug resistance in cancer: The early years of P-glycoprotein research Fulltext Access 12 Pages 2006
Roles of ethylene receptor NTHK1 domains in plant growth, stress response and protein phosphorylation Fulltext Access 12 Pages 2006
STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein β-catenin recognized by a selective monoclonal antibody Fulltext Access 12 Pages 2006
Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine Fulltext Access 12 Pages 2006
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response Fulltext Access 12 Pages 2006
Deletion of DDB1 in Mouse Brain and Lens Leads to p53-Dependent Elimination of Proliferating Cells Fulltext Access 12 Pages 2006
The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin Fulltext Access 12 Pages 2006
Perception of the Bacterial PAMP EF-Tu by the Receptor EFR Restricts Agrobacterium-Mediated Transformation Fulltext Access 12 Pages 2006
A Checkpoint Protein That Scans the Chromosome for Damage at the Start of Sporulation in Bacillus subtilis Fulltext Access 12 Pages 2006
Crystal Structure of the CSL-Notch-Mastermind Ternary Complex Bound to DNA Fulltext Access 12 Pages 2006
In Vitro Reconstitution of Eukaryotic Translation Reveals Cooperativity between Release Factors eRF1 and eRF3 Fulltext Access 12 Pages 2006
Sequence-Resolved Detection of Pausing by Single RNA Polymerase Molecules Fulltext Access 12 Pages 2006
Sequential Quality-Control Checkpoints Triage Misfolded Cystic Fibrosis Transmembrane Conductance Regulator Fulltext Access 12 Pages 2006
A Novel Role for High-Mobility Group A Proteins in Cellular Senescence and Heterochromatin Formation Fulltext Access 12 Pages 2006
New Evidence Supporting Megakaryocyte-Erythrocyte Potential of Flk2/Flt3+ Multipotent Hematopoietic Progenitors Fulltext Access 12 Pages 2006
Tertiary Contacts Distant from the Active Site Prime a Ribozyme for Catalysis Fulltext Access 12 Pages 2006
Cockayne Syndrome A and B Proteins Differentially Regulate Recruitment of Chromatin Remodeling and Repair Factors to Stalled RNA Polymerase II In Vivo Fulltext Access 12 Pages 2006
Combinatorial Analysis of Transcription Factor Partners Reveals Recruitment of c-MYC to Estrogen Receptor-α Responsive Promoters Fulltext Access 12 Pages 2006
Condensin I Interacts with the PARP-1-XRCC1 Complex and Functions in DNA Single-Strand Break Repair Fulltext Access 12 Pages 2006
A Homotrimer–Heterotrimer Switch in Sir2 Structure Differentiates rDNA and Telomeric Silencing Fulltext Access 12 Pages 2006
Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase Fulltext Access 12 Pages 2006
Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1 Fulltext Access 12 Pages 2006
Differential Regulation of EGF Receptor Internalization and Degradation by Multiubiquitination within the Kinase Domain Fulltext Access 12 Pages 2006
The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Fulltext Access 12 Pages 2006
Proteomic Profiling of ClpXP Substrates after DNA Damage Reveals Extensive Instability within SOS Regulon Fulltext Access 12 Pages 2006
A Spliceosomal Intron Binding Protein, IBP160, Links Position-Dependent Assembly of Intron-Encoded Box C/D snoRNP to Pre-mRNA Splicing Fulltext Access 12 Pages 2006
Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions Fulltext Access 12 Pages 2006
Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey Fulltext Access 12 Pages 2006
The E3 SUMO Ligase PIASy Is a Regulator of Cellular Senescence and Apoptosis Fulltext Access 12 Pages 2006
SeqA Blocking of DnaA-oriC Interactions Ensures Staged Assembly of the E. coli Pre-RC Fulltext Access 12 Pages 2006
Architecture of the 99 bp DNA-Six-Protein Regulatory Complex of the λ att Site Fulltext Access 12 Pages 2006
Evaluation of a Diffusion-Driven Mechanism for Substrate Ubiquitination by the SCF-Cdc34 Ubiquitin Ligase Complex Fulltext Access 12 Pages 2006
Mapping the Phosphoinositide-Binding Site on Chick Cofilin Explains How PIP2 Regulates the Cofilin-Actin Interaction Fulltext Access 12 Pages 2006
SV40 VP2 and VP3 Insertion into ER Membranes Is Controlled by the Capsid Protein VP1: Implications for DNA Translocation out of the ER Fulltext Access 12 Pages 2006
Mechanistic Insights into Sulfur Relay by Multiple Sulfur Mediators Involved in Thiouridine Biosynthesis at tRNA Wobble Positions Fulltext Access 12 Pages 2006
Coherence and Timing of Cell Cycle Start Examined at Single-Cell Resolution Fulltext Access 12 Pages 2006
Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric ABC Transporter Fulltext Access 12 Pages 2006
ATP Binding and ATP Hydrolysis Play Distinct Roles in the Function of 26S Proteasome Fulltext Access 12 Pages 2006
Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer Fulltext Access 12 Pages 2006
Identification of an Intestinal Folate Transporter and the Molecular Basis for Hereditary Folate Malabsorption Fulltext Access 12 Pages 2006
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators Fulltext Access 12 Pages 2006
Structural Analysis of E. coli hsp90 Reveals Dramatic Nucleotide-Dependent Conformational Rearrangements Fulltext Access 12 Pages 2006
Insulin Degrading Enzyme Is a Cellular Receptor Mediating Varicella-Zoster Virus Infection and Cell-to-Cell Spread Fulltext Access 12 Pages 2006
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q Fulltext Access 12 Pages 2006
UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Fulltext Access 12 Pages 2006
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells Fulltext Access 12 Pages 2006
Synergistic Functions of SII and p300 in Productive Activator-Dependent Transcription of Chromatin Templates Fulltext Access 12 Pages 2006
Resolution of Chiasmata in Oocytes Requires Separase-Mediated Proteolysis Fulltext Access 12 Pages 2006
A Transient Heterochromatic State in Xist Preempts X Inactivation Choice without RNA Stabilization Fulltext Access 12 Pages 2006
A Nitric Oxide Signaling Pathway Controls CREB-Mediated Gene Expression in Neurons Fulltext Access 12 Pages 2006
Crystal Structure of a Cbf5-Nop10-Gar1 Complex and Implications in RNA-Guided Pseudouridylation and Dyskeratosis Congenita Fulltext Access 12 Pages 2006
Opening Closed Arms: Long-Distance Activation of SMC ATPase by Hinge-DNA Interactions Fulltext Access 12 Pages 2006
The Control Mechanism for Lagging Strand Polymerase Recycling during Bacteriophage T4 DNA Replication Fulltext Access 12 Pages 2006
Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds through a Concerted β Strand Displacement Mechanism Fulltext Access 12 Pages 2006
Is Dimerization Required for the Catalytic Activity of Bacterial Biotin Carboxylase? Fulltext Access 12 Pages 2006
IRBIT Suppresses IP3 Receptor Activity by Competing with IP3 for the Common Binding Site on the IP3 Receptor Fulltext Access 12 Pages 2006