Downregulation of PP2ACdc55 Phosphatase by Separase Initiates Mitotic Exit in Budding Yeast Fulltext Access 14 Pages 2006
Systems Analyses Reveal Two Chaperone Networks with Distinct Functions in Eukaryotic Cells Fulltext Access 14 Pages 2006
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents Fulltext Access 14 Pages 2006
Type II Cadherin Ectodomain Structures: Implications for Classical Cadherin Specificity Fulltext Access 14 Pages 2006
A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator Fulltext Access 14 Pages 2006
The LDL Receptor-Related Protein LRP6 Mediates Internalization and Lethality of Anthrax Toxin Fulltext Access 14 Pages 2006
A Protein–Protein Interaction Network for Human Inherited Ataxias and Disorders of Purkinje Cell Degeneration Fulltext Access 14 Pages 2006
Nontranscriptional Regulation of SYK by the Coactivator OCA-B Is Required at Multiple Stages of B Cell Development Fulltext Access 14 Pages 2006
Ex Vivo Rapamycin Generates Th1/Tc1 or Th2/Tc2 Effector T Cells With Enhanced In Vivo Function and Differential Sensitivity to Post-transplant Rapamycin Therapy Fulltext Access 14 Pages 2006
Germ-Cell Loss Extends C. elegans Life Span through Regulation of DAF-16 by kri-1 and Lipophilic-Hormone Signaling Fulltext Access 14 Pages 2006
Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress Fulltext Access 14 Pages 2006
rRNA Promoter Regulation by Nonoptimal Binding of σ Region 1.2: An Additional Recognition Element for RNA Polymerase Fulltext Access 14 Pages 2006
Drosophila IKK-Related Kinase Regulates Nonapoptotic Function of Caspases via Degradation of IAPs Fulltext Access 14 Pages 2006
A Role for the Deubiquitinating Enzyme USP28 in Control of the DNA-Damage Response Fulltext Access 14 Pages 2006
In Vivo Two-Photon Imaging Reveals a Role of Arc in Enhancing Orientation Specificity in Visual Cortex Fulltext Access 14 Pages 2006
Histone Deacetylase 7 Maintains Vascular Integrity by Repressing Matrix Metalloproteinase 10 Fulltext Access 14 Pages 2006
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain Fulltext Access 14 Pages 2006
Copulatory organ musculature in Childia (Acoela) as revealed by phalloidin fluorescence and confocal microscopy Fulltext Access 14 Pages 2006
Prismatic dentine in the Australian lungfish, Neoceratodus forsteri (Osteichthyes: Dipnoi) Fulltext Access 14 Pages 2006
Mammalian RGS proteins: Multifunctional regulators of cellular signalling Fulltext Access 14 Pages 2006
A role for Wnt/planar cell polarity signaling during lens fiber cell differentiation? Fulltext Access 14 Pages 2006
The role of the lens actin cytoskeleton in fiber cell elongation and differentiation Fulltext Access 14 Pages 2006
Phosphorylation on Ser106 Modulates the Cellular Functions of the SHOX Homeodomain Protein Fulltext Access 14 Pages 2006
The Major Outer Membrane Protein of Fusobacterium nucleatum (FomA) Folds and Inserts into Lipid Bilayers via Parallel Folding Pathways Fulltext Access 14 Pages 2006
GATC Flanking Sequences Regulate Dam Activity: Evidence for how Dam Specificity may Influence pap Expression Fulltext Access 14 Pages 2006
Integrin α3 subunit participates in myoblast adhesion and fusion in vitro Fulltext Access 14 Pages 2006
Cells differentiated from mouse embryonic stem cells via embryoid bodies express renal marker molecules Fulltext Access 14 Pages 2006
Blown fuse regulates stretching and outgrowth but not myoblast fusion of the circular visceral muscles in Drosophila Fulltext Access 14 Pages 2006
Spatiotemporal Feedback between Actomyosin and Focal-Adhesion Systems Optimizes Rapid Cell Migration Fulltext Access 14 Pages 2006
Using small molecules to overcome drug resistance induced by a viral oncogene Fulltext Access 14 Pages 2006
Forced homo-oligomerization of RARα leads to transformation of primary hematopoietic cells Fulltext Access 14 Pages 2006
Forced retinoic acid receptor α homodimers prime mice for APL-like leukemia Fulltext Access 14 Pages 2006
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages Fulltext Access 14 Pages 2006
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis Fulltext Access 14 Pages 2006
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors Fulltext Access 14 Pages 2006
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia Fulltext Access 14 Pages 2006
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo Fulltext Access 14 Pages 2006
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint Fulltext Access 14 Pages 2006
A negative feedback signaling network underlies oncogene-induced senescence Fulltext Access 14 Pages 2006
Recommended Screening and Preventive Practices for Long-term Survivors after Hematopoietic Cell Transplantation: Joint Recommendations of the European Group for Blood and Marrow Transplantation, the Center for International Blood and Marrow Transplant Res Fulltext Access 14 Pages 2006
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells Fulltext Access 14 Pages 2006
The Structure of the ζζ Transmembrane Dimer Reveals Features Essential for Its Assembly with the T Cell Receptor Fulltext Access 14 Pages 2006
CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta Fulltext Access 14 Pages 2006
Global Survey of Organ and Organelle Protein Expression in Mouse: Combined Proteomic and Transcriptomic Profiling Fulltext Access 14 Pages 2006
Structural and Functional Organization of the ESCRT-I Trafficking Complex Fulltext Access 14 Pages 2006
The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage Fulltext Access 14 Pages 2006
Target-Induced Transcriptional Control of Dendritic Patterning and Connectivity in Motor Neurons by the ETS Gene Pea3 Fulltext Access 14 Pages 2006
The Proteasome Restricts Permissive Transcription at Tissue-Specific Gene Loci in Embryonic Stem Cells Fulltext Access 14 Pages 2006
A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging Fulltext Access 14 Pages 2006
Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa Fulltext Access 14 Pages 2006
Toxoplasma gondii Sequesters Lysosomes from Mammalian Hosts in the Vacuolar Space Fulltext Access 14 Pages 2006
Redox Regulation Facilitates Optimal Peptide Selection by MHC Class I during Antigen Processing Fulltext Access 14 Pages 2006
An ARGONAUTE4-Containing Nuclear Processing Center Colocalized with Cajal Bodies in Arabidopsis thaliana Fulltext Access 14 Pages 2006
The Arabidopsis Chromatin-Modifying Nuclear siRNA Pathway Involves a Nucleolar RNA Processing Center Fulltext Access 14 Pages 2006
Pot1 Deficiency Initiates DNA Damage Checkpoint Activation and Aberrant Homologous Recombination at Telomeres Fulltext Access 14 Pages 2006
The subcellular fractionation properties and function of insulin receptor substrate-1 (IRS-1) are independent of cytoskeletal integrity Fulltext Access 14 Pages 2006
The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C Fulltext Access 14 Pages 2006
Dipeptidyl peptidase IV inhibitors: A promising new therapeutic approach for the management of type 2 diabetes Fulltext Access 14 Pages 2006
In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion Fulltext Access 14 Pages 2006
Geminin is bound to chromatin in G2/M phase to promote proper cytokinesis Fulltext Access 14 Pages 2006
RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward Fulltext Access 14 Pages 2006
A Protein Kinase, Interacting with Two Calcineurin B-like Proteins, Regulates K+ Transporter AKT1 in Arabidopsis Fulltext Access 14 Pages 2006
Intracellular Nucleotides Act as Critical Prosurvival Factors by Binding to Cytochrome C and Inhibiting Apoptosome Fulltext Access 14 Pages 2006
The Pattern of Gene Amplification Is Determined by the Chromosomal Location of Hairpin-Capped Breaks Fulltext Access 14 Pages 2006
Ubiquitin Hydrolase Uch-L1 Rescues β-Amyloid-Induced Decreases in Synaptic Function and Contextual Memory Fulltext Access 14 Pages 2006
ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation Fulltext Access 14 Pages 2006
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Fulltext Access 14 Pages 2006
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks Fulltext Access 14 Pages 2006
The BRCA1/BARD1 Heterodimer Modulates Ran-Dependent Mitotic Spindle Assembly Fulltext Access 14 Pages 2006
Ubc9- and Mms21-Mediated Sumoylation Counteracts Recombinogenic Events at Damaged Replication Forks Fulltext Access 14 Pages 2006
Increased Ethanol Resistance and Consumption in Eps8 Knockout Mice Correlates with Altered Actin Dynamics Fulltext Access 14 Pages 2006
RalB GTPase-Mediated Activation of the IκB Family Kinase TBK1 Couples Innate Immune Signaling to Tumor Cell Survival Fulltext Access 14 Pages 2006
Human neoplastic mesothelial cells express voltage-gated sodium channels involved in cell motility Fulltext Access 14 Pages 2006
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth Fulltext Access 14 Pages 2006
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells Fulltext Access 14 Pages 2006
Developmental Origin of a Bipotential Myocardial and Smooth Muscle Cell Precursor in the Mammalian Heart Fulltext Access 14 Pages 2006
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α Fulltext Access 14 Pages 2006
The Architecture of the Multisubunit TRAPP I Complex Suggests a Model for Vesicle Tethering Fulltext Access 14 Pages 2006
E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation Fulltext Access 14 Pages 2006
Ligand-Induced Asymmetry in Histidine Sensor Kinase Complex Regulates Quorum Sensing Fulltext Access 14 Pages 2006
Kinetochore Microtubule Dynamics and Attachment Stability Are Regulated by Hec1 Fulltext Access 14 Pages 2006
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis Fulltext Access 14 Pages 2006
Gradients of the Drosophila Chinmo BTB-Zinc Finger Protein Govern Neuronal Temporal Identity Fulltext Access 14 Pages 2006