Towards understanding the interaction between oligosaccharides and water molecules Fulltext Access 14 Pages 2005
Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase Fulltext Access 14 Pages 2005
Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase Fulltext Access 14 Pages 2005
Synthesis and biological evaluation of new symmetrical derivatives as cytotoxic agents and apoptosis inducers Fulltext Access 14 Pages 2005
Mapping enzymatic functionalities of mannuronan C-5 epimerases and their modular units by dynamic force spectroscopy Fulltext Access 14 Pages 2005
Complex O-acetylation in non-typeable Haemophilus influenzae lipopolysaccharide: evidence for a novel site of O-acetylation Fulltext Access 14 Pages 2005
Effect of saccharide length on the immunogenicity of neoglycoconjugates from synthetic fragments of the O-SP of Vibrio cholerae O1, serotype Ogawa Fulltext Access 14 Pages 2005
On the generalized valence bond description of the anomeric and exo-anomeric effects: an ab initio conformational study of 2-methoxytetrahydropyran Fulltext Access 14 Pages 2005
Structure–affinity relationship studies of non-competitive NMDA receptor antagonists derived from dexoxadrol and etoxadrol Fulltext Access 14 Pages 2005
Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy-α,β-unsaturated sugar aldehydes derived from respective glycals Fulltext Access 14 Pages 2005
α-cycloalkyl-substituted Ï-keto-dicarboxylic acids as lipid regulating agents Fulltext Access 14 Pages 2005
Diphenylcyclohexylamine derivatives as new potent multidrug resistance (MDR) modulators Fulltext Access 14 Pages 2005
Hantzsch 1,4-dihydropyridines containing a diazen-1-ium-1,2-diolate nitric oxide donor moiety to study calcium channel antagonist structure-activity relationships and nitric oxide release Fulltext Access 14 Pages 2005
Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-l-prolyl-l-glutamic acid (GPE) Fulltext Access 14 Pages 2005
Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues Fulltext Access 14 Pages 2005
Discovery of 1,7-cyclized indoles as a new class of potent and highly selective human β3-adrenergic receptor agonists with high cell permeability Fulltext Access 14 Pages 2005
Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure Fulltext Access 14 Pages 2005
Selective anti-tubercular purines: Synthesis and chemotherapeutic properties of 6-aryl- and 6-heteroaryl-9-benzylpurines Fulltext Access 14 Pages 2005
QSAR modeling of blood:air and tissue:air partition coefficients using theoretical descriptors Fulltext Access 14 Pages 2005
Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites Fulltext Access 14 Pages 2005
Terpene trilactones from Gingko biloba: From ancient times to the 21st century Fulltext Access 14 Pages 2005
Nuclear receptor antagonists designed based on the helix-folding inhibition hypothesis Fulltext Access 14 Pages 2005
Substrate specificity of the bovine serum amine oxidase and in situ characterisation of aminoaldehydes by NMR spectroscopy Fulltext Access 14 Pages 2005
1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: Synthesis, biological evaluation, and molecular modeling study Fulltext Access 14 Pages 2005
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation Fulltext Access 14 Pages 2005
Lysine–spermine conjugates: hydrophobic polyamine amides as potent lipopolysaccharide sequestrants Fulltext Access 14 Pages 2005
Synthesis and pharmacological evaluation of benzamide derivatives as selective 5-HT4 receptor agonists Fulltext Access 14 Pages 2005
Role of CpG islands in the up-regulation of NMDA receptor NR2B gene expression following chronic ethanol treatment of cultured cortical neurons of mice Fulltext Access 15 Pages 2005
Pertussis-toxin-sensitive Gα subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex Fulltext Access 15 Pages 2005
Stereoselective synthesis of E-64 and related cysteine proteases inhibitors from 2,3-epoxyamides Fulltext Access 15 Pages 2005
Acute and chronic continuous methamphetamine have different long-term behavioral and neurochemical consequences Fulltext Access 15 Pages 2005
Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues Fulltext Access 15 Pages 2005
Concise syntheses of arabinogalactans with β-(1â6)-linked galactopyranose backbones and α-(1â3)- and α-(1â2)-linked arabinofuranose side chains Fulltext Access 15 Pages 2005
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridin-(5H)ones Fulltext Access 15 Pages 2005
N-Acyl-N-alkyl-sulfonamide anchors derived from Kenner's safety-catch linker: powerful tools in bioorganic and medicinal chemistry Fulltext Access 15 Pages 2005
Activation of p38 and p42/44 MAP kinase in neuropathic pain: Involvement of VPAC2 and NK2 receptors and mediation by spinal glia Fulltext Access 15 Pages 2005
Characterization of four receptor cDNAs: PAC1, VPAC1, a novel PAC1 and a partial GHRH in zebrafish Fulltext Access 15 Pages 2005
Corepressor subnuclear organization is regulated by estrogen receptor via a mechanism that requires the DNA-binding domain Fulltext Access 15 Pages 2005
Selective hormone-dependent repression of estrogen receptor beta by a p38-activated ErbB2/ErbB3 pathway Fulltext Access 15 Pages 2005
Effects of dehydroepiandrosterone, Premarin and Acolbifene on histomorphology and sex steroid receptors in the rat vagina Fulltext Access 15 Pages 2005
Increased Wnt levels in the neural tube impair the function of adherens junctions during neurulation Fulltext Access 15 Pages 2005
Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels Fulltext Access 15 Pages 2005
Anterograde axonal transport of BDNF and NT-3 by retinal ganglion cells: Roles of neurotrophin receptors Fulltext Access 15 Pages 2005
Structural analysis of xyloglucans in the primary cell walls of plants in the subclass Asteridae Fulltext Access 15 Pages 2005
Detection and measurement of alternative splicing using splicing-sensitive microarrays Fulltext Access 15 Pages 2005
New aspects of the location of neuronal nitric oxide synthase in the skeletal muscle: A light and electron microscopic study Fulltext Access 15 Pages 2005
Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo Fulltext Access 15 Pages 2005
Disinhibition of neurotrophin-induced dorsal root ganglion cell neurite outgrowth on CNS myelin by siRNA-mediated knockdown of NgR, p75NTR and Rho-A Fulltext Access 15 Pages 2005
Production of pediocin PA-1 in the methylotrophic yeast Pichia pastoris reveals unexpected inhibition of its biological activity due to the presence of collagen-like material Fulltext Access 15 Pages 2005
Two separate metalloproteinase activities are responsible for the shedding and processing of the NG2 proteoglycan in vitro Fulltext Access 15 Pages 2005
Matrix metalloproteases: degradation of the inhibitory environment of the transected optic nerve and the scar by regenerating axons Fulltext Access 15 Pages 2005
Description of complete DNA sequence of two plasmids from the nukacin ISK-1 producer, Staphylococcus warneri ISK-1 Fulltext Access 15 Pages 2005
Lipopolysaccharide and lipoteichoic acid induce different innate immune responses in bovine mammary epithelial cells Fulltext Access 15 Pages 2005
The multidrug resistance protein BMDP/ABCG2: A new and highly relevant efflux pump at the blood-brain barrier Fulltext Access 15 Pages 2005
The priorities/needs of the pharmaceutical industry in drug delivery to the brain Fulltext Access 15 Pages 2005
A physically interpretable quantum-theoretic QSAR for some carbonic anhydrase inhibitors with diverse aromatic rings, obtained by a new QSAR procedure Fulltext Access 15 Pages 2005
Structure–activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors Fulltext Access 15 Pages 2005
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity Fulltext Access 15 Pages 2005
A comparative study of MHC Class-II HLA-DRβ1*0401-Col II and HLA-DRβ1*0101-HA complexes: a theoretical point of view Fulltext Access 15 Pages 2005
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies Fulltext Access 15 Pages 2005
Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: Synthesis and kinetic characterization as aminopeptidase P inhibitors Fulltext Access 15 Pages 2005
A novel class of sodium/calcium exchanger inhibitor: design, synthesis, and structure–activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives Fulltext Access 15 Pages 2005
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide Fulltext Access 15 Pages 2005
C3′-cis-Substituted carboxycyclopropyl glycines as metabotropic glutamate 2/3 receptor agonists: Synthesis and SAR studies Fulltext Access 15 Pages 2005
Molecular modeling, design, synthesis, and biological evaluation of novel 3′,4′-dicamphanoyl-(+)-cis-khellactone (DCK) analogs as potent anti-HIV agents Fulltext Access 15 Pages 2005
Molecular evidence for the polyphyly of the genus Hemitragus (Mammalia, Bovidae) Fulltext Access 15 Pages 2005
Ecomorphological diversification among South American spiny rats (Rodentia; Echimyidae): a phylogenetic and chronological approach Fulltext Access 15 Pages 2005
Extensive paraphylies within sharks of the order Carcharhiniformes inferred from nuclear and mitochondrial genes Fulltext Access 15 Pages 2005
A molecular phylogenetic analysis of the “true thrushes” (Aves: Turdinae) Fulltext Access 15 Pages 2005
Systematics and evolution of the subfamily Gerbillinae (Mammalia, Rodentia, Muridae) Fulltext Access 15 Pages 2005
Model-based multi-locus estimation of decapod phylogeny and divergence times Fulltext Access 15 Pages 2005
Evolutionary history of freshwater sculpins, genus Cottus (Teleostei; Cottidae) and related taxa, as inferred from mitochondrial DNA phylogeny Fulltext Access 15 Pages 2005
Mitochondrial phylogeny of pine cone beetles (Scolytinae, Conophthorus) and their affiliation with geographic area and host Fulltext Access 15 Pages 2005
Enzymes involved in the formation and transformation of steroid hormones in the fetal and placental compartments Fulltext Access 15 Pages 2005
Evolution and phylogeography of Halimeda section Halimeda (Bryopsidales, Chlorophyta) Fulltext Access 15 Pages 2005
Nuclear ribosomal DNA and karyotypes indicate a NW African origin of South American Hypochaeris (Asteraceae, Cichorieae) Fulltext Access 15 Pages 2005
Phylogeny and biogeography of the freshwater crayfish Euastacus (Decapoda: Parastacidae) based on nuclear and mitochondrial DNA Fulltext Access 15 Pages 2005
Phylogenetic and phylogeographic relationships in the crayfish genus Austropotamobius inferred from mitochondrial COI gene sequences Fulltext Access 15 Pages 2005
Molecular phylogenetics and evolution of host plant use in the Neotropical rolled leaf 'hispine' beetle genus Cephaloleia (Chevrolat) (Chrysomelidae: Cassidinae) Fulltext Access 15 Pages 2005
Gelechioidea (Insecta: Lepidoptera) systematics: A reexamination using combined morphology and mitochondrial DNA data Fulltext Access 15 Pages 2005
Gene expression in Plasmodium berghei ookinetes and early oocysts in a co-culture system with mosquito cells Fulltext Access 15 Pages 2005
An expressed sequence tag analysis of the life-cycle of the parasitic nematode Strongyloides ratti Fulltext Access 15 Pages 2005