Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H2O2-induced apoptosis Fulltext Access 13 Pages 2010
Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway Fulltext Access 13 Pages 2010
Hepatotoxicity of di-(2-ethylhexyl)phthalate is attributed to calcium aggravation, ROS-mediated mitochondrial depolarization, and ERK/NF-κB pathway activation Fulltext Access 13 Pages 2010
Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition Fulltext Access 13 Pages 2010
Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell–cell detachment and processing of adhesion molecules via mechanisms that involve PKC Fulltext Access 13 Pages 2010
Novel role of pleckstrin homology domain of the Bcr-Abl protein: Analysis of protein-protein and protein-lipid interactions Fulltext Access 13 Pages 2010
YB1/p32, a nuclear Y-box binding protein 1, is a novel regulator of myoblast differentiation that interacts with Msx1 homeoprotein Fulltext Access 13 Pages 2010
Bcl-2 sustains hormetic response by inducing Nrf-2 nuclear translocation in L929 mouse fibroblasts Fulltext Access 13 Pages 2010
Long-lasting inhibition of presynaptic metabolism and neurotransmitter release by protein S-nitrosylation Fulltext Access 13 Pages 2010
The NRF2–heme oxygenase-1 system modulates cyclosporin A-induced epithelial–mesenchymal transition and renal fibrosis Fulltext Access 13 Pages 2010
Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLCγ1 and JAK2 phosphorylation Fulltext Access 13 Pages 2010
Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor α liver injury Fulltext Access 13 Pages 2010
Reactive γ-ketoaldehydes formed via the isoprostane pathway disrupt mitochondrial respiration and calcium homeostasis Fulltext Access 13 Pages 2010
Candida albicans heme oxygenase and its product CO contribute to pathogenesis of candidemia and alter systemic chemokine and cytokine expression Fulltext Access 13 Pages 2010
Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia–reperfusion injury and treatment Fulltext Access 13 Pages 2010
Hypoxic neonatal pulmonary arterial myocytes are sensitized to ROS-generated 8-isoprostane Fulltext Access 13 Pages 2010
Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca2+/c-Abl signaling pathway Fulltext Access 13 Pages 2010
Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity Fulltext Access 13 Pages 2010
Patient selection—risk assessment and anatomical selection criteria for patients undergoing transfemoral aortic valve implantation Fulltext Access 13 Pages 2010
The pro-oxidant chromium(VI) inhibits mitochondrial complex I, complex II, and aconitase in the bronchial epithelium: EPR markers for Fe–S proteins Fulltext Access 13 Pages 2010
Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity Fulltext Access 13 Pages 2010
Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target Fulltext Access 13 Pages 2010
Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro Fulltext Access 13 Pages 2010
Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy Fulltext Access 14 Pages 2010
Polynuclear water-soluble dinitrosyl iron complexes with cysteine or glutathione ligands: Electron paramagnetic resonance and optical studies Fulltext Access 14 Pages 2010
Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming Fulltext Access 14 Pages 2010
miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1 Fulltext Access 14 Pages 2010
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells Fulltext Access 14 Pages 2010
Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1 Fulltext Access 14 Pages 2010
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer Fulltext Access 14 Pages 2010
The role of erythropoietin and its receptor in growth, survival and therapeutic response of human tumor cells: From clinic to bench — a critical review Fulltext Access 14 Pages 2010
Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro Fulltext Access 14 Pages 2010
Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms Fulltext Access 14 Pages 2010
Virus–host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach Fulltext Access 14 Pages 2010
Oxidative-stress-induced alterations in Sp factors mediate transcriptional regulation of the NR1 subunit in hippocampus during hypoxia Fulltext Access 14 Pages 2010
Proteomic analysis of common bean seed with storage protein deficiency reveals up-regulation of sulfur-rich proteins and starch and raffinose metabolic enzymes, and down-regulation of the secretory pathway Fulltext Access 14 Pages 2010
Mass spectrometric characterization of isoform variants of peanut (Arachis hypogaea) stem lectin (SL-I) Fulltext Access 14 Pages 2010
Proteome analysis of mouse model systems: A tool to model human disease and for the investigation of tissue-specific biology Fulltext Access 14 Pages 2010
Two-dimensional gel electrophoresis in proteomics: Past, present and future Fulltext Access 14 Pages 2010
Molecular pathways regulating CD4+ T cell differentiation, anergy and memory with implications for vaccines Fulltext Access 14 Pages 2010
FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts Fulltext Access 14 Pages 2010
CREBBP Re-arrangements affect protein function and lead to aberrant neuronal differentiation Fulltext Access 14 Pages 2010
Proteolytic cleavage of chemokines by Trypanosoma cruzi's cruzipain inhibits chemokine functions by promoting the generation of antagonists Fulltext Access 14 Pages 2010
Polyreactive antibodies in multidonor-derived immunoglobulin G: Theory and conclusions drawn from experiments Fulltext Access 14 Pages 2010
The early lymphocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis compared to infection status Fulltext Access 14 Pages 2010
Fluorine-18 radiopharmaceuticals beyond [18F]FDG for use in oncology and neurosciences Fulltext Access 14 Pages 2010
Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing Fulltext Access 14 Pages 2010
BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway Fulltext Access 14 Pages 2010
In vitro treatments with ceftriaxone promote elimination of mutant glial fibrillary acidic protein and transcription down-regulation Fulltext Access 14 Pages 2010
Up-regulation of the embryonic self-renewal network through reversible polyploidy in irradiated p53-mutant tumour cells Fulltext Access 14 Pages 2010
Dimerization drives PDGF receptor endocytosis through a C-terminal hydrophobic motif shared by EGF receptor Fulltext Access 14 Pages 2010
Endothelial nitric oxide synthase is essential for nitric oxide generation, L-type Ca2+ channel activation and survival in RBL-2H3 mast cells Fulltext Access 14 Pages 2010
Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents Fulltext Access 14 Pages 2010
Structure–activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters Fulltext Access 14 Pages 2010
Efficient synthesis and identification of novel propane-1,3-diamino bridged CCR5 antagonists with variation on the basic center carrier Fulltext Access 14 Pages 2010
In vivo and in vitro evaluation of highly specific thiolate carrier group copper(II) and zinc(II) complexes on Ehrlich ascites carcinoma tumor model Fulltext Access 14 Pages 2010
Computational structure–activity relationship analysis of small-molecule agonists for human formyl peptide receptors Fulltext Access 14 Pages 2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids Fulltext Access 14 Pages 2010
Novel structural insights for drug design of selective 5-HT2C inverse agonists from a ligand-biased receptor model Fulltext Access 14 Pages 2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans Fulltext Access 14 Pages 2010
Asymmetrically substituted cationic indole- and fluorene porphyrins inhibit tumor proliferation in small intestinal neuroendocrine tumors and medullary thyroid carcinomas Fulltext Access 14 Pages 2010
Novel quinoline and naphthalene derivatives as potent antimycobacterial agents Fulltext Access 14 Pages 2010
Structure–activity relationships of indole compounds derived from combretastatin A4: Synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents Fulltext Access 14 Pages 2010
Synthesis and optimization of antitubercular activities in a series of 4-(aryloxy)phenyl cyclopropyl methanols Fulltext Access 14 Pages 2010
Serum profile in preeclampsia and intra-uterine growth restriction revealed by iTRAQ technology Fulltext Access 14 Pages 2010
Studies on glyphosate-induced carcinogenicity in mouse skin: A proteomic approach Fulltext Access 14 Pages 2010
Pre-analytical factors in clinical proteomics investigations: Impact of ex vivo protein modifications for multiple sclerosis biomarker discovery Fulltext Access 14 Pages 2010
Exosomes: Extracellular organelles important in intercellular communication Fulltext Access 14 Pages 2010
Quantitative proteome profiling of respiratory virus-infected lung epithelial cells Fulltext Access 14 Pages 2010
Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms Fulltext Access 14 Pages 2010
Cytosolic phospholipase A2-α enhances induction of endoplasmic reticulum stress Fulltext Access 14 Pages 2010
Telomere susceptibility to cigarette smoke-induced oxidative damage and chromosomal instability of mouse embryos in vitro Fulltext Access 14 Pages 2010
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells Fulltext Access 14 Pages 2010
Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging? Fulltext Access 14 Pages 2010
Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention Fulltext Access 14 Pages 2010
Noble metal targeting of thioredoxin reductase — covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin Fulltext Access 14 Pages 2010
CD44 and hyaluronan promote invasive growth of B35 neuroblastoma cells into the brain Fulltext Access 14 Pages 2010
Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death Fulltext Access 14 Pages 2010
Muscle degeneration in neuraminidase 1-deficient mice results from infiltration of the muscle fibers by expanded connective tissue Fulltext Access 14 Pages 2010
Genetics of primary hypertension: The clinical impact of adducin polymorphisms Fulltext Access 14 Pages 2010
Azetidine derivatives as novel γ-aminobutyric acid uptake inhibitors: Synthesis, biological evaluation, and structure–activity relationship Fulltext Access 14 Pages 2010
A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein Fulltext Access 14 Pages 2010
Three-dimensional quantitative structure–activity relationship CoMSIA/CoMFA and LeapFrog studies on novel series of bicyclo [4.1.0] heptanes derivatives as melanin-concentrating hormone receptor R1 antagonists Fulltext Access 14 Pages 2010