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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Syntrophin-2 is required for eye development in Drosophila
Fulltext Access 14 Pages 2010
A conserved peptide motif in Raver2 mediates its interaction with the polypyrimidine tract-binding protein
Fulltext Access 14 Pages 2010
Impairment of VEGF-A-stimulated lamellipodial extensions and motility of vascular endothelial cells by chondromodulin-I, a cartilage-derived angiogenesis inhibitor
Fulltext Access 14 Pages 2010
Hypoglycosylated E-cadherin promotes the assembly of tight junctions through the recruitment of PP2A to adherens junctions
Fulltext Access 14 Pages 2010
A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: Activation of proteinase-activated receptor 1 and epidermal growth factor receptor
Fulltext Access 14 Pages 2010
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells
Fulltext Access 14 Pages 2010
M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation
Fulltext Access 14 Pages 2010
Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic β-cells by promoting insulin gene transcription
Fulltext Access 14 Pages 2010
Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling
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CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)
Fulltext Access 14 Pages 2010
A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes
Fulltext Access 14 Pages 2010
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence
Fulltext Access 14 Pages 2010
Dynamin-like protein 1 at the Golgi complex: A novel component of the sorting/targeting machinery en route to the plasma membrane
Fulltext Access 14 Pages 2010
Kaiso regulates Znf131-mediated transcriptional activation
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8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway
Fulltext Access 14 Pages 2010
VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop
Fulltext Access 14 Pages 2010
Sef is a negative regulator of fiber cell differentiation in the ocular lens
Fulltext Access 15 Pages 2010
TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration
Fulltext Access 15 Pages 2010
In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells
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Sdc1 negatively modulates carcinoma cell motility and invasion
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Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells
Fulltext Access 15 Pages 2010
Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn
Fulltext Access 15 Pages 2010
Secretome proteomics for discovery of cancer biomarkers
Fulltext Access 15 Pages 2010
MicroRNAs: Oncogenes, tumor suppressors or master regulators of cancer heterogeneity?
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EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells
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Acute ligand-independent Src activation mimics low EGF-induced EGFR surface signalling and redistribution into recycling endosomes
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Caveolin-1 mutants P132L and Y14F are dominant negative regulators of invasion, migration and aggregation in H1299 lung cancer cells
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Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells
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Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs
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Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells
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Characterisation of degranulation and phagocytic capacity of a human neutrophilic cellular model, PLB-985 cells
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Phosphoproteomic characterization of PYK2 signaling pathways involved in osteogenesis
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Proteomic profiling of intestinal prechylomicron transport vesicle (PCTV)-associated proteins in an animal model of insulin resistance (94 char)
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The Drosophila melanogaster sperm proteome-II (DmSP-II)
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Ion channels and the hallmarks of cancer
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Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL
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The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism
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Vγ9+ γδ T cells in systemic sclerosis patients are numerically and functionally preserved and induce fibroblast apoptosis
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Cannabis-based medicines in multiple sclerosis – A review of clinical studies
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Glial cell line-derived neurotrophic factor alters the growth characteristics and genomic imprinting of mouse multipotent adult germline stem cells
Fulltext Access 15 Pages 2010
Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth
Fulltext Access 15 Pages 2010
Protrusion and actin assembly are coupled to the organization of lamellar contractile structures
Fulltext Access 15 Pages 2010
The mammalian Verprolin, WIRE induces filopodia independent of N-WASP through IRSp53
Fulltext Access 15 Pages 2010
Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells
Fulltext Access 15 Pages 2010
Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration
Fulltext Access 15 Pages 2010
Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction
Fulltext Access 15 Pages 2010
Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1
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Synthesis and biological evaluation of cinnamido linked pyrrolo[2,1-c][1,4]benzodiazepines as antimitotic agents
Fulltext Access 15 Pages 2010
Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction
Fulltext Access 15 Pages 2010
Quantitative structure–antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4′-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: Trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4′-O-β-D-glucopyran
Fulltext Access 15 Pages 2010
Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1′- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents
Fulltext Access 15 Pages 2010
Investigation on the isoform selectivity of histone deacetylase inhibitors using chemical feature based pharmacophore and docking approaches
Fulltext Access 15 Pages 2010
Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays
Fulltext Access 15 Pages 2010
Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: Synthesis, evaluation and SAR
Fulltext Access 15 Pages 2010
Synthesis and evaluation of indole, pyrazole, chromone and pyrimidine based conjugates for tumor growth inhibitory activities – Development of highly efficacious cytotoxic agents
Fulltext Access 15 Pages 2010
Computational analysis of ligand recognition sites of homo- and heteropentameric 5-HT3 receptors
Fulltext Access 15 Pages 2010
3D QSAR studies on ketoamides of human cathepsin K inhibitors based on two different alignment methods
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Graphical contents list
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Discovery of novel CDK1 inhibitors by combining pharmacophore modeling, QSAR analysis and in silico screening followed by in vitro bioassay
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Prognostic markers and putative therapeutic targets for hepatocellular carcinoma
Fulltext Access 15 Pages 2010
1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoi
Fulltext Access 15 Pages 2010
Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring
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Lead identification of conformationally restricted β-lactam type combretastatin analogues: Synthesis, antiproliferative activity and tubulin targeting effects
Fulltext Access 15 Pages 2010
The egg white and yolk interactomes as gleaned from extensive proteomic data
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Proteome of Gluconacetobacter diazotrophicus co-cultivated with sugarcane plantlets
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Cancer-specific MALDI-TOF profiles of blood serum and plasma: Biological meaning and perspectives
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Umbilical cord blood stem cells: Towards a proteomic approach
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Red Blood Cell (RBC) membrane proteomics — Part II: Comparative proteomics and RBC patho-physiology
Fulltext Access 15 Pages 2010
Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids
Fulltext Access 15 Pages 2010
Proteomic analysis of wheat embryos with 2-DE and liquid-phase chromatography (ProteomeLab PF-2D) — A wider perspective of the proteome
Fulltext Access 15 Pages 2010
Induction of COX-2/PGE2/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation
Fulltext Access 15 Pages 2010
The Warburg effect and mitochondrial stability in cancer cells
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HIV-1 Vif versus the APOBEC3 cytidine deaminases: An intracellular duel between pathogen and host restriction factors
Fulltext Access 15 Pages 2010
Influence of spontaneous calcium events on cell-cycle progression in embryonal carcinoma and adult stem cells
Fulltext Access 15 Pages 2010
Vrp1p–Las17p interaction is critical for actin patch polarization but is not essential for growth or fluid phase endocytosis in S. cerevisiae
Fulltext Access 15 Pages 2010
2010 Award Winners, Contributors, Exhibitors, SFRBM Council, Abstract Reviewers, and Future Meetings
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Oxidative stress and glutathione in TGF-β-mediated fibrogenesis
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Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
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Peroxynitrite mediates right-ventricular dysfunction in nitric oxide-exposed juvenile rats
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Graphical contents list
Fulltext Access 15 Pages 2010
Transgenic models for cytokine-induced neurological disease
Fulltext Access 15 Pages 2010
Graphical contents list
Fulltext Access 15 Pages 2010
Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: Implications for iron-related dopaminergic neuron degeneration
Fulltext Access 16 Pages 2010
Common and distinct roles for the binding partners Rabenosyn-5 and Vps45 in the regulation of endocytic trafficking in mammalian cells
Fulltext Access 16 Pages 2010
Diagnostic and prognostic biomarker discovery strategies for autoimmune disorders
Fulltext Access 16 Pages 2010
Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers
Fulltext Access 16 Pages 2010
Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress
Fulltext Access 16 Pages 2010
The endogenous peptides of normal human serum extracted from the acetonitrile-insoluble precipitate using modified aqueous buffer with analysis by LC–ESI–Paul ion trap and Qq-TOF
Fulltext Access 16 Pages 2010
Synthesis and pharmacological evaluation of novel fused thiophene derivatives as 5-HT2A receptor antagonists: Molecular modeling study
Fulltext Access 16 Pages 2010
Abstracts to be presented at the 18th Meeting of the Japan Placenta Association 2010, 30 September-1 October 2010 Kumamoto, Japan
Fulltext Access 16 Pages 2010
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species
Fulltext Access 16 Pages 2010
Mitochondrial dysfunction in Parkinson's disease
Fulltext Access 16 Pages 2010
NBCn1 and NHE1 expression and activity in ΔNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance
Fulltext Access 16 Pages 2010
In-vivo visualization of key molecular processes involved in Alzheimer's disease pathogenesis: Insights from neuroimaging research in humans and rodent models
Fulltext Access 16 Pages 2010
Regulation of cell adhesion to collagen via β1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon
Fulltext Access 16 Pages 2010
The role of the autonomic nervous liver innervation in the control of energy metabolism
Fulltext Access 16 Pages 2010
Identification of ZASP, a novel protein associated to Zona occludens-2
Fulltext Access 16 Pages 2010
Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN
Fulltext Access 16 Pages 2010
Limited Ca2+ and PKA-pathway dependent neurogenic differentiation of human adult mesenchymal stem cells as compared to fetal neuronal stem cells
Fulltext Access 16 Pages 2010
Structure–activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines
Fulltext Access 16 Pages 2010
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