Functional characterization of the microtubule-binding and -destabilizing domains of CPAP and d-SAS-4 Fulltext Access 12 Pages 2008
Two wobble-splicing events affect ING4 protein subnuclear localization and degradation Fulltext Access 12 Pages 2008
Functional involvement of human discs large tumor suppressor in cytokinesis Fulltext Access 12 Pages 2008
Requirement of the conserved, hydrophobic C-terminus region for the activation of heparanase Fulltext Access 12 Pages 2008
Sorting of the v-SNARE VAMP7 in Dictyostelium discoideum: A role for more than one Adaptor Protein (AP) complex Fulltext Access 12 Pages 2008
Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration Fulltext Access 12 Pages 2008
Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons Fulltext Access 12 Pages 2008
TGFβ stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling Fulltext Access 12 Pages 2008
Caenorhabditis elegans par2.1/mtssb-1 is essential for mitochondrial DNA replication and its defect causes comprehensive transcriptional alterations including a hypoxia response Fulltext Access 12 Pages 2008
Neural crest motility on fibronectin is regulated by integrin activation Fulltext Access 12 Pages 2008
Multiple effects of TRAIL in human carcinoma cells: Induction of apoptosis, senescence, proliferation, and cytokine production Fulltext Access 12 Pages 2008
Transient down-regulation of cbfa1/Runx2 by RNA interference in murine C3H10T1/2 mesenchymal stromal cells delays in vitro and in vivo osteogenesis, but does not overtly affect chondrogenesis Fulltext Access 12 Pages 2008
Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei Fulltext Access 12 Pages 2008
Laminin α5 mediates ectopic adhesion of hepatocellular carcinoma through integrins and/or Lutheran/basal cell adhesion molecule Fulltext Access 12 Pages 2008
Mitogen-activated protein kinase up-regulation and activation during rat parotid gland atrophy and regeneration: role of epidermal growth factor and β2-adrenergic receptors Fulltext Access 12 Pages 2008
CD2-associated protein is widely expressed and differentially regulated during embryonic development Fulltext Access 12 Pages 2008
The Prader–Willi syndrome protein necdin interacts with the E1A-like inhibitor of differentiation EID-1 and promotes myoblast differentiation Fulltext Access 12 Pages 2008
Comparative osteogenic transcription profiling of various fetal and adult mesenchymal stem cell sources Fulltext Access 12 Pages 2008
The efficiency of Xenopus primordial germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein Grip2 Fulltext Access 12 Pages 2008
Three-dimensional epidermis-like growth of human mesenchymal stem cells on dermal equivalents: contribution to tissue organization by adaptation of myofibroblastic phenotype and function Fulltext Access 12 Pages 2008
Multilineage differentiation potential of equine blood-derived fibroblast-like cells Fulltext Access 12 Pages 2008
Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices Fulltext Access 12 Pages 2008
Overexpression of COUP-TF1 in murine embryonic stem cells reduces retinoic acid-associated growth arrest and increases extraembryonic endoderm gene expression Fulltext Access 12 Pages 2008
Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion Fulltext Access 12 Pages 2008
Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span Fulltext Access 12 Pages 2008
Oxidative Stress Contributes to Aging by Enhancing Pancreatic Angiogenesis and Insulin Signaling Fulltext Access 12 Pages 2008
Interference with PPARγ Function in Smooth Muscle Causes Vascular Dysfunction and Hypertension Fulltext Access 12 Pages 2008
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance Fulltext Access 12 Pages 2008
Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy Fulltext Access 12 Pages 2008
Nutritional Control of Protein Biosynthetic Capacity by Insulin via Myc in Drosophila Fulltext Access 12 Pages 2008
Opposing Effects of Dietary Protein and Sugar Regulate a Transcriptional Target of Drosophila Insulin-like Peptide Signaling Fulltext Access 12 Pages 2008
Serotonin Regulates C. elegans Fat and Feeding through Independent Molecular Mechanisms Fulltext Access 12 Pages 2008
The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1 Fulltext Access 12 Pages 2008
Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance Fulltext Access 12 Pages 2008
Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation Fulltext Access 12 Pages 2008
Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration Fulltext Access 12 Pages 2008
Effects of Oxygen on Cell Turnover and Expression of Regulators of Apoptosis in Human Placental Trophoblast Fulltext Access 12 Pages 2008
Modeling Trophoblast Differentiation using Equine Chorionic Girdle Vesicles Fulltext Access 12 Pages 2008
Live and Let Die – Regulation of Villous Trophoblast Apoptosis in Normal and Abnormal Pregnancies Fulltext Access 12 Pages 2008
S-nitrosylation of proteins at the leading edge of migrating trophoblasts by inducible nitric oxide synthase promotes trophoblast invasion Fulltext Access 12 Pages 2008
Autophagy modulates keratin-containing inclusion formation and apoptosis in cell culture in a context-dependent fashion Fulltext Access 12 Pages 2008
Interactions of myeloma cells with osteoclasts promote tumour expansion and bone degradation through activation of a complex signalling network and upregulation of cathepsin K, matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA) Fulltext Access 12 Pages 2008
Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes Fulltext Access 12 Pages 2008
Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene Fulltext Access 12 Pages 2008
Drosophila mars is required for organizing kinetochore microtubules during mitosis Fulltext Access 12 Pages 2008
Extracellular superoxide released from mitochondria mediates mast cell death by advanced glycation end products Fulltext Access 12 Pages 2008
SRC-dependent signalling regulates actin ruffle formation induced by glycerophosphoinositol 4-phosphate Fulltext Access 12 Pages 2008
Chemoenzymatic synthesis and antimicrobial activity evaluation of monogalactosyl diglycerides Fulltext Access 12 Pages 2008
Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors Fulltext Access 12 Pages 2008
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents Fulltext Access 12 Pages 2008
Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors Fulltext Access 12 Pages 2008
In silico prediction of brain and CSF permeation of small molecules using PLS regression models Fulltext Access 12 Pages 2008
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies Fulltext Access 12 Pages 2008
Computational aqueous solubility prediction for drug-like compounds in congeneric series Fulltext Access 12 Pages 2008
An efficient tool for identifying inhibitors based on 3D-QSAR and docking using feature-shape pharmacophore of biologically active conformation – A case study with CDK2/CyclinA Fulltext Access 12 Pages 2008
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines Fulltext Access 12 Pages 2008
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant Fulltext Access 12 Pages 2008
The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization Fulltext Access 12 Pages 2008
Binding mode analysis and enrichment studies on homology models of the human histamine H4 receptor Fulltext Access 12 Pages 2008
Inhibition of immune complex-mediated neutrophil oxidative metabolism: A pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures Fulltext Access 12 Pages 2008
QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa Fulltext Access 12 Pages 2008
Snake venomics of the Armenian mountain vipers Macrovipera lebetina obtusa and Vipera raddei Fulltext Access 12 Pages 2008
Mass spectrometric and linear discriminant analysis of N-glycans of human serum alpha-1-acid glycoprotein in cancer patients and healthy individuals Fulltext Access 12 Pages 2008
The effect of the bacterial effector protein harpin on transcriptional profile and mitochondrial proteins of Arabidopsis thaliana Fulltext Access 12 Pages 2008
Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD Fulltext Access 12 Pages 2008
Evaluation of three different protocols of protein extraction for Arabidopsis thaliana leaf proteome analysis by two-dimensional electrophoresis Fulltext Access 12 Pages 2008
Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells Fulltext Access 12 Pages 2008
Bone morphogenetic protein signaling in the developing kidney: present and future Fulltext Access 12 Pages 2008
MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse Fulltext Access 12 Pages 2008
The Emergence of Hematopoietic Stem Cells Is Initiated in the Placental Vasculature in the Absence of Circulation Fulltext Access 12 Pages 2008
Brain Area-Specific Effect of TGF-β Signaling on Wnt-Dependent Neural Stem Cell Expansion Fulltext Access 12 Pages 2008
Genetic Modification of Human Embryonic Stem Cells for Derivation of Target Cells Fulltext Access 12 Pages 2008
Nf1 Mutation Expands an EGFR-Dependent Peripheral Nerve Progenitor that Confers Neurofibroma Tumorigenic Potential Fulltext Access 12 Pages 2008
Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation Fulltext Access 12 Pages 2008
Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells Fulltext Access 12 Pages 2008
Role of NonO–histone interaction in TNFα-suppressed Prolyl-4-hydroxylase α1 Fulltext Access 12 Pages 2008
Cartilage–hair hypoplasia-associated mutations in the RNase MRP P3 domain affect RNA folding and ribonucleoprotein assembly Fulltext Access 12 Pages 2008
Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells — A novel mechanism of action of a photodynamic tumor therapy agent Fulltext Access 12 Pages 2008
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis Fulltext Access 12 Pages 2008
Overexpression of phospholipase D suppresses taxotere-induced cell death in stomach cancer cells Fulltext Access 12 Pages 2008
Store-operated Ca2+ channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells Fulltext Access 12 Pages 2008
Involvement of Ymer in suppression of NF-κB activation by regulated interaction with lysine-63-linked polyubiquitin chain Fulltext Access 12 Pages 2008
A lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation Fulltext Access 12 Pages 2008