Laminin-5-deficient human keratinocytes: Defective adhesion results in a saltatory and inefficient mode of migration Fulltext Access 13 Pages 2007
The Parkinson’s disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase thatstimulates kinase activity Fulltext Access 13 Pages 2007
Level of endothelial cell apoptosis required for a significant decrease in microvessel density Fulltext Access 13 Pages 2007
Cytolinker cross-talk: Periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration Fulltext Access 13 Pages 2007
CagA-independent disruption of adherence junction complexes involves E-cadherin shedding and implies multiple steps in Helicobacter pylori pathogenicity Fulltext Access 13 Pages 2007
15-Deoxy-Î12,14-prostaglandin J2 down-regulates CXCR4 on carcinoma cells through PPARγ- and NFκB-mediated pathways Fulltext Access 13 Pages 2007
A role for the Rab6B Bicaudal–D1 interaction in retrograde transport in neuronal cells Fulltext Access 13 Pages 2007
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress Fulltext Access 13 Pages 2007
1,25-Dihydroxyvitamin D3 induces biphasic NF-κB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IκB Fulltext Access 13 Pages 2007
Organization of cytokeratin cytoskeleton and germ plasm in the vegetal cortex of Xenopus laevis oocytes depends on coding and non-coding RNAs: Three-dimensional and ultrastructural analysis Fulltext Access 13 Pages 2007
Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness Fulltext Access 13 Pages 2007
Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor α signalling Fulltext Access 13 Pages 2007
Human estrogen receptor α gene is a target of Runx2 transcription factor in osteoblasts Fulltext Access 13 Pages 2007
Translation regulation after taxol treatment in NIH3T3 cells involves the elongation factor (eEF)2 Fulltext Access 13 Pages 2007
Morphological changes and nuclear translocation of DLC1 tumor suppressor protein precede apoptosis in human non-small cell lung carcinoma cells Fulltext Access 13 Pages 2007
Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: Evidence for a role of α5-laminin(s) and α3β1 integrin Fulltext Access 13 Pages 2007
RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line Fulltext Access 13 Pages 2007
Mechano-transduction mediated secretion and uptake of galectin-3 in breast carcinoma cells: Implications in the extracellular functions of the lectin Fulltext Access 13 Pages 2007
Structural and functional analysis of the sarcoglycan–sarcospan subcomplex Fulltext Access 13 Pages 2007
Characterization of STIP, a multi-domain nuclear protein, highly conserved in metazoans, and essential for embryogenesis in Caenorhabditis elegans Fulltext Access 13 Pages 2007
Accelerated de novo sarcomere assembly by electric pulse stimulation in C2C12 myotubes Fulltext Access 13 Pages 2007
Expression and upregulation of cathepsin S and other early molecules required for antigen presentation in activated hepatic stellate cells upon IFN-γ treatment Fulltext Access 13 Pages 2007
VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2 Fulltext Access 13 Pages 2007
Distinct functional domains in nesprin-1α and nesprin-2β bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy Fulltext Access 13 Pages 2007
Tyrosine kinase inhibitor, methyl 2,5-dihydromethylcinnimate, induces PML nuclear body formation and apoptosis in tumor cells Fulltext Access 13 Pages 2007
Identification of the Drosophila eIF4A gene as a target of the DREF transcription factor Fulltext Access 13 Pages 2007
Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI) Fulltext Access 13 Pages 2007
Neuronal distribution of Spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17 Fulltext Access 13 Pages 2007
Serotonin-1A receptor imaging in recurrent depression: replication and literature review Fulltext Access 13 Pages 2007
Towards a molecular description of intermediate filament structure and assembly Fulltext Access 13 Pages 2007
Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives Fulltext Access 13 Pages 2007
Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes Fulltext Access 13 Pages 2007
Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase Fulltext Access 13 Pages 2007
EHD proteins are associated with tubular and vesicular compartments and interact with specific phospholipids Fulltext Access 13 Pages 2007
RACK1 regulates Src activity and modulates paxillin dynamics during cell migration Fulltext Access 13 Pages 2007
‘Working’ cardiomyocytes exhibiting plateau action potentials from human placenta-derived extraembryonic mesodermal cells Fulltext Access 13 Pages 2007
Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b Fulltext Access 13 Pages 2007
Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin Fulltext Access 13 Pages 2007
ADP ribosylation factor like 2 (Arl2) protein influences microtubule dynamics in breast cancer cells Fulltext Access 13 Pages 2007
Two different pathways are involved in peroxynitrite-induced senescence and apoptosis of human erythrocytes Fulltext Access 13 Pages 2007
High sensitivity of human centrin 2 toward radiolytical oxidation: C-terminal tyrosinyl residue as the main target Fulltext Access 13 Pages 2007
NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis Fulltext Access 13 Pages 2007
The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome Fulltext Access 13 Pages 2007
Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia Fulltext Access 13 Pages 2007
Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro Fulltext Access 13 Pages 2007
Insulin-induced impairment via peroxynitrite production of endothelium-dependent relaxation and sarco/endoplasmic reticulum Ca2+-ATPase function in aortas from diabetic rats Fulltext Access 13 Pages 2007
Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane) Fulltext Access 13 Pages 2007
Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: Role of NADPH oxidase-derived ROS Fulltext Access 13 Pages 2007
Activation of the death receptor pathway of apoptosis by the aldehyde acrolein Fulltext Access 13 Pages 2007
Novel role of IL-6/SIL-6R signaling in the expression of inducible nitric oxide synthase (iNOS) in murine B16, metastatic melanoma clone F10.9, cells Fulltext Access 13 Pages 2007
Oculopharyngeal muscular dystrophy: Recent advances in the understanding of the molecular pathogenic mechanisms and treatment strategies Fulltext Access 13 Pages 2007
Altered expression of FHL1, CARP, TSC-22 and P311 provide insights into complex transcriptional regulation in pacing-induced atrial fibrillation Fulltext Access 13 Pages 2007
Annexin V is directly involved in cystic fibrosis transmembrane conductance regulator's chloride channel function Fulltext Access 13 Pages 2007
Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells Fulltext Access 13 Pages 2007
The consequences of scoring docked ligand conformations using free energy correlations Fulltext Access 13 Pages 2007
Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra® series Fulltext Access 13 Pages 2007
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study Fulltext Access 13 Pages 2007
Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains Fulltext Access 13 Pages 2007
Membrane cholesterol in the regulation of aminophospholipid asymmetry and phagocytosis in oxidized erythrocytes Fulltext Access 13 Pages 2007
Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death Fulltext Access 13 Pages 2007
Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation Fulltext Access 13 Pages 2007
TGFβ1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members Fulltext Access 13 Pages 2007
Four thiol peroxidases contain a conserved GCT catalytic motif and act as a versatile array of lipid peroxidases in Anabaena sp. PCC7120 Fulltext Access 13 Pages 2007
Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway Fulltext Access 13 Pages 2007
Hydrogen peroxide induces nitric oxide and proteosome activity in endothelial cells: A bell-shaped signaling response Fulltext Access 13 Pages 2007
Ozone enhancement of lower airway allergic inflammation is prevented by γ-tocopherol Fulltext Access 13 Pages 2007
Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F Fulltext Access 13 Pages 2007
Methods to detect nitric oxide and its metabolites in biological samples Fulltext Access 13 Pages 2007
An evolutionarily conserved 16-kDa thioredoxin-related protein is an antioxidant which regulates the NF-κB signaling pathway Fulltext Access 13 Pages 2007
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome Fulltext Access 13 Pages 2007
Lack of extracellular superoxide dismutase (EC-SOD) in the microenvironment impacts radiation-induced changes in neurogenesis Fulltext Access 13 Pages 2007
ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment Fulltext Access 13 Pages 2007
Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages Fulltext Access 13 Pages 2007
Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice Fulltext Access 13 Pages 2007
Reduced thioredoxin increases proinflammatory cytokines and neutrophil influx in rat airways: Modulation by airway mucus Fulltext Access 13 Pages 2007
Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression Fulltext Access 14 Pages 2007
Intermittent hypoxia changes HIF-1α phosphorylation pattern in endothelial cells: Unravelling of a new PKA-dependent regulation of HIF-1α Fulltext Access 14 Pages 2007
A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice Fulltext Access 14 Pages 2007
Impaired mitochondrial Ca2+ homeostasis in respiratory chain-deficient cells but efficient compensation of energetic disadvantage by enhanced anaerobic glycolysis due to low ATP steady state levels Fulltext Access 14 Pages 2007
Regulation of gene transcription by mitogen-activated protein kinase signaling pathways Fulltext Access 14 Pages 2007