Synthesis and biological evaluation of new steroidal pyridines as potential anti-prostate cancer agents Fulltext Access 31 Pages 2018
Remodeling of the cardiovascular circulation in fetuses of mothers with diabetes: A fetal computational model analysis Fulltext Access 31 Pages 2018
Synthesis and bio-inspired optimization of drimenal: Discovery of chiral drimane fused oxazinones as promising antifungal and antibacterial candidates Fulltext Access 31 Pages 2018
Development of novel anti-filarial agents using carbamo(dithioperoxo)thioate derivatives Fulltext Access 31 Pages 2018
Phenome and genome based studies into human ageing and longevity: An overview Fulltext Access 31 Pages 2018
Altered nuclear envelope structure and proteasome function of micronuclei Fulltext Access 31 Pages 2018
The role of compartmentalized signaling pathways in the control of mitochondrial activities in cancer cells Fulltext Access 31 Pages 2018
Development of a data independent acquisition mass spectrometry workflow to enable glycopeptide analysis without predefined glycan compositional knowledge Fulltext Access 31 Pages 2018
Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts Fulltext Access 32 Pages 2018
The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma Fulltext Access 32 Pages 2018
Synthesis and biological evaluation of diarylheptanoids as potential antioxidant and anti-inflammatory agents Fulltext Access 32 Pages 2018
Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect Fulltext Access 32 Pages 2018
Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production Fulltext Access 32 Pages 2018
Foetoplacental epigenetic changes associated with maternal metabolic dysfunction Fulltext Access 32 Pages 2018
Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma Fulltext Access 32 Pages 2018
Potential targets for therapeutic intervention and structure based vaccine design against Zika virus Fulltext Access 32 Pages 2018
Hybrid compounds from chalcone and 1,2-benzothiazine pharmacophores as selective inhibitors of alkaline phosphatase isozymes Fulltext Access 32 Pages 2018
Recent advances in the rational design and development of LIM kinase inhibitors are not enough to enter clinical trials Fulltext Access 32 Pages 2018
Molecular hydrogen reduces acute exercise-induced inflammatory and oxidative stress status Fulltext Access 32 Pages 2018
Synthesis and biological evaluation of Schizandrin derivatives as potential anti-cancer agents Fulltext Access 32 Pages 2018
Pyrazole-pyrazoline as promising novel antimalarial agents: A mechanistic study Fulltext Access 32 Pages 2018
Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives Fulltext Access 32 Pages 2018
Exogenous hydrogen sulfide protects from endothelial cell damage, platelet activation, and neutrophils extracellular traps formation in hyperhomocysteinemia rats Fulltext Access 32 Pages 2018
Distinct mechanisms enable inward or outward budding from late endosomes/multivesicular bodies Fulltext Access 33 Pages 2018
Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor Fulltext Access 33 Pages 2018
Treatment of de novo coronary artery bifurcation lesions with drug coated balloons: A reappraisal according to the available scientific data Fulltext Access 33 Pages 2018
Estrogen alleviates neuropathic pain induced after spinal cord injury by inhibiting microglia and astrocyte activation Fulltext Access 33 Pages 2018
Cardiorespiratory responses, nitric oxide production and inflammatory factors in patients with myocardial infarction after rehabilitation Fulltext Access 33 Pages 2018
New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling Fulltext Access 33 Pages 2018
Mitochondrial therapy promotes regeneration of injured hippocampal neurons Fulltext Access 33 Pages 2018
Macrophage-derived superoxide production and antioxidant response following skeletal muscle injury Fulltext Access 33 Pages 2018
Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration Fulltext Access 33 Pages 2018
Investigating human placentation and pregnancy using first trimester chorionic villi Fulltext Access 33 Pages 2018
Prenylated flavonoids as potent phosphodiesterase-4 inhibitors from Morus alba: Isolation, modification, and structure-activity relationship study Fulltext Access 33 Pages 2018
Inorganic nitrate supplementation enhances functional capacity and lower-limb microvascular reactivity in patients with peripheral artery disease Fulltext Access 33 Pages 2018
Design, synthesis and biological evaluation of novel quinazoline-2,4-diones conjugated with different amino acids as potential chitin synthase inhibitors Fulltext Access 33 Pages 2018
Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives Fulltext Access 33 Pages 2018
Proteomics as a tool to understand Leptospira physiology and virulence: Recent advances, challenges and clinical implications Fulltext Access 34 Pages 2018
Exploring putative genetic determinants of inter-individual phenotypic heterogeneity in sickle cell disease: A cross-sectional Jamaican cohort-based study Fulltext Access 34 Pages 2018
Prevalence and Effects of Emphysema in Never-Smokers with Rheumatoid Arthritis Interstitial Lung Disease Fulltext Access 34 Pages 2018
Genomic Analysis Reveals Distinct Subtypes in Two Rare Cases of Primary Ovarian Lymphoma Fulltext Access 34 Pages 2018
Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies Fulltext Access 34 Pages 2018
Hematopoietic changes in the offspring induced by maternal overweight: Effect on placenta and fetal liver populations Fulltext Access 34 Pages 2018
Energy metabolic capacities of human adipose-derived mesenchymal stromal cells in vitro and their adaptations in osteogenic and adipogenic differentiation Fulltext Access 34 Pages 2018
Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects Fulltext Access 34 Pages 2018
Mutual influence of sleep and circadian clocks on physiology and cognition Fulltext Access 34 Pages 2018
Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases Fulltext Access 34 Pages 2018
Inhibition of myeloid differentiation factor-2 attenuates obesity-induced cardiomyopathy and fibrosis Fulltext Access 34 Pages 2018
Symmetrical and unsymmetrical substituted 2,5-diarylidene cyclohexanones as anti-parasitic compounds Fulltext Access 34 Pages 2018
An oxidation-resistant, recombinant alpha-1 antitrypsin produced in Nicotiana benthamiana Fulltext Access 34 Pages 2018
Synthesis, crystal structure and antimicrobial potential of some fluorinated chalcone-1,2,3-triazole conjugates Fulltext Access 35 Pages 2018
Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells Fulltext Access 35 Pages 2018
Elucidation of the dynamic nature of interactome networks: A practical tutorial Fulltext Access 35 Pages 2018
Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity Fulltext Access 35 Pages 2018
The role of placental malperfusion in the pathogenesis of preeclampsia in dichorionic twin and singleton pregnancies Fulltext Access 35 Pages 2018
The use of Brazilian propolis for discovery and development of novel anti-inflammatory drugs Fulltext Access 35 Pages 2018
Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening Fulltext Access 35 Pages 2018
Proteomic profiling of rectal cancer reveals acid ceramidase is implicated in radiation response Fulltext Access 35 Pages 2018
Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents Fulltext Access 35 Pages 2018
Proteomic profiling of the brain of mice with experimental cerebral malaria Fulltext Access 35 Pages 2018
Blue light phototoxicity toward human corneal and conjunctival epithelial cells in basal and hyperosmolar conditions Fulltext Access 35 Pages 2018
Differential targeting of membrane lipid domains by caffeic acid and its ester derivatives Fulltext Access 35 Pages 2018
The intracellular domain of the leptin receptor prevents mitochondrial depolarization and mitophagy Fulltext Access 35 Pages 2018
Activity of nitric oxide synthase isoforms in acute brain oxidative damage induced by ozone exposure Fulltext Access 35 Pages 2018
Neuronal nitric oxide synthase regulation of skeletal muscle functional hyperemia: exercise training and moderate compensated heart failure Fulltext Access 35 Pages 2018
Peptides having antimicrobial activity and their complexes with transition metal ions Fulltext Access 35 Pages 2018
Mechanisms of canalicular transporter endocytosis in the cholestatic rat liver Fulltext Access 35 Pages 2018
Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity Fulltext Access 35 Pages 2018
Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs Fulltext Access 35 Pages 2018
Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines Fulltext Access 36 Pages 2018
Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia Fulltext Access 36 Pages 2018
New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening Fulltext Access 36 Pages 2018
Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives Fulltext Access 36 Pages 2018
Recent progress in the structural modification and pharmacological activities of ligustrazine derivatives Fulltext Access 36 Pages 2018
Rational modification of a lead molecule: Improving the antifungal activity of indole - triazole - amino acid conjugates Fulltext Access 36 Pages 2018
Design, synthesis and evaluation of amino-substituted 1H-phenalen-1-ones as anti-leishmanial agents Fulltext Access 36 Pages 2018
Nano-liposomes of lycopene reduces ischemic brain damage in rodents by regulating iron metabolism Fulltext Access 36 Pages 2018
Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation Fulltext Access 36 Pages 2018
Monitoring cellular redox state under hypoxia using a fluorescent sensor based on eel fluorescent protein Fulltext Access 36 Pages 2018
Loss of thioredoxin 2 alters mitochondrial respiratory function and induces cardiomyocyte hypertrophy Fulltext Access 36 Pages 2018
Synthesis and biological evaluation of new water-soluble photoactive chlorin conjugate for targeted delivery Fulltext Access 36 Pages 2018