P. aeruginosa PilT Structures with and without Nucleotide Reveal a Dynamic Type IV Pilus Retraction Motor Fulltext Access 11 Pages 2010
Structural Conservation of Components in the Amino Acid Sensing Branch of the TOR Pathway in Yeast and Mammals Fulltext Access 11 Pages 2010
Structure of Isoprene Synthase Illuminates the Chemical Mechanism of Teragram Atmospheric Carbon Emission Fulltext Access 11 Pages 2010
The Down-regulation of the Human MYC Gene by the Nuclear Hormone 1α,25-dihydroxyvitamin D3 is Associated with Cycling of Corepressors and Histone Deacetylases Fulltext Access 11 Pages 2010
The Interaction of Equine Lysozyme:Oleic Acid Complexes with Lipid Membranes Suggests a Cargo Off-Loading Mechanism Fulltext Access 11 Pages 2010
Analysis of the Open and Closed Conformations of the β Subunits in Thermophilic F1-ATPase by Solution NMR Fulltext Access 11 Pages 2010
Computational and Experimental Evidence for the Evolution of a (βα)8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds Fulltext Access 11 Pages 2010
Crystal Structures of the Multidrug Binding Repressor Corynebacterium glutamicum CgmR in Complex with Inducers and with an Operator Fulltext Access 11 Pages 2010
Structural Determinants for Improved Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module Fulltext Access 11 Pages 2010
Evolved Lactococcus lactis Strains for Enhanced Expression of Recombinant Membrane Proteins Fulltext Access 11 Pages 2010
Multiple Unfolding Events during Native Folding of the Tetrahymena Group I Ribozyme Fulltext Access 11 Pages 2010
Structural and Mechanical Hierarchies in the α-Crystallin Domain Dimer of the Hyperthermophilic Small Heat Shock Protein Hsp16.5 Fulltext Access 11 Pages 2010
ϕ29 DNA Polymerase Active Site: Role of Residue Val250 as Metal–dNTP Complex Ligand and in Protein-Primed Initiation Fulltext Access 11 Pages 2010
High-Resolution Orientation and Depth of Insertion of the Voltage-Sensing S4 Helix of a Potassium Channel in Lipid Bilayers Fulltext Access 11 Pages 2010
ATP Binding, ATP Hydrolysis, and Protein Dimerization Are Required for RecF to Catalyze an Early Step in the Processing and Recovery of Replication Forks Disrupted by DNA Damage Fulltext Access 11 Pages 2010
Action of the Chaperonin GroEL/ES on a Non-native Substrate Observed with Single-Molecule FRET Fulltext Access 11 Pages 2010
Structure and Engineering of l-Arabinitol 4-Dehydrogenase from Neurospora crassa Fulltext Access 11 Pages 2010
Use of RNA Tertiary Interaction Modules for the Crystallisation of the Spliceosomal snRNP Core Domain Fulltext Access 11 Pages 2010
Context-Dependent Remodeling of Structure in Two Large Protein Fragments Fulltext Access 11 Pages 2010
Recognition of Nucleoside Monophosphate Substrates by Haemophilus influenzae Class C Acid Phosphatase Fulltext Access 11 Pages 2010
Biosynthesis of Isoprenoids: Crystal Structure of the [4Fe–4S] Cluster Protein IspG Fulltext Access 11 Pages 2010
A Simple Definition of Structural Regions in Proteins and Its Use in Analyzing Interface Evolution Fulltext Access 11 Pages 2010
Identification of Critical Residues for the Tight Binding of Both Correct and Incorrect Nucleotides to Human DNA Polymerase λ Fulltext Access 11 Pages 2010
Structure of Human Cytosolic Phenylalanyl-tRNA Synthetase: Evidence for Kingdom-Specific Design of the Active Sites and tRNA Binding Patterns Fulltext Access 11 Pages 2010
Automated multi-model reconstruction from single-particle electron microscopy data Fulltext Access 11 Pages 2010
A new member of the ribbon-helix-helix transcription factor superfamily from the plant pathogen Xanthomonas axonopodis pv. citri Fulltext Access 11 Pages 2010
Predicted 3D structures for adenosine receptors bound to ligands: Comparison to the crystal structure Fulltext Access 11 Pages 2010
Specific coiled-coil interactions contribute to a global model of the structure of the spindle pole body Fulltext Access 11 Pages 2010
Recent advances in the production of proteins in insect and mammalian cells for structural biology Fulltext Access 11 Pages 2010
Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression Fulltext Access 11 Pages 2010
Polymeric Structures and Dynamic Properties of the Bacterial Actin AlfA Fulltext Access 11 Pages 2010
Cleavage Specificity of Enterococcus faecalis EnpA (EF1473), a Peptidoglycan Endopeptidase Related to the LytM/Lysostaphin Family of Metallopeptidases Fulltext Access 11 Pages 2010
Inhibition of Collagen Fibrillogenesis by Cells Expressing Soluble Extracellular Domains of DDR1 and DDR2 Fulltext Access 11 Pages 2010
Ligand-Mediated Dimerization of the Met Receptor Tyrosine Kinase by the Bacterial Invasion Protein InlB Fulltext Access 11 Pages 2010
Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2 Fulltext Access 11 Pages 2010
Structural Basis of TBX5–DNA Recognition: The T-Box Domain in Its DNA-Bound and -Unbound Form Fulltext Access 11 Pages 2010
Structural and Biochemical Characterization of a Halophilic Archaeal Alkaline Phosphatase Fulltext Access 11 Pages 2010
Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism Fulltext Access 11 Pages 2010
Structural Basis of the Action of Glucosyltransferase Lgt1 from Legionella pneumophila Fulltext Access 11 Pages 2010
Structural Basis for the Recognition and Cleavage of Polysialic Acid by the Bacteriophage K1F Tailspike Protein EndoNF Fulltext Access 11 Pages 2010
Crystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes Fulltext Access 11 Pages 2010
Structure of the Membrane Domain of Human Erythrocyte Anion Exchanger 1 Revealed by Electron Crystallography Fulltext Access 11 Pages 2010
The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction Fulltext Access 11 Pages 2010
Combination of the Loss of cmnm5U34 with the Lack of s2U34 Modifications of tRNALys, tRNAGlu, and tRNAGln Altered Mitochondrial Biogenesis and Respiration Fulltext Access 11 Pages 2010
Solution Structure of an Active Mutant of Maize Ribosome-Inactivating Protein (MOD) and Its Interaction with the Ribosomal Stalk Protein P2 Fulltext Access 11 Pages 2010
Pin1At Encoding a Peptidyl-Prolyl cis/trans Isomerase Regulates Flowering Time in Arabidopsis Fulltext Access 11 Pages 2010
Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function Fulltext Access 11 Pages 2010
Spindle Position Is Coordinated with Cell-Cycle Progression through Establishment of Mitotic Exit-Activating and -Inhibitory Zones Fulltext Access 11 Pages 2010
Sin1-mTORC2 Suppresses rag and il7r Gene Expression through Akt2 in B Cells Fulltext Access 11 Pages 2010
Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine Fulltext Access 11 Pages 2010
The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing Fulltext Access 11 Pages 2010
Structural Basis for Substrate Placement by an Archaeal Box C/D Ribonucleoprotein Particle Fulltext Access 11 Pages 2010
H2A.Z Maintenance during Mitosis Reveals Nucleosome Shifting on Mitotically Silenced Genes Fulltext Access 11 Pages 2010
Swi2/Snf2-Related Translocases Prevent Accumulation of Toxic Rad51 Complexes during Mitotic Growth Fulltext Access 11 Pages 2010
Strand Invasion Structures in the Inverted Repeat of Candida albicans Mitochondrial DNA Reveal a Role for Homologous Recombination in Replication Fulltext Access 11 Pages 2010
Distinct Phases of siRNA Synthesis in an Endogenous RNAi Pathway in C. elegans Soma Fulltext Access 11 Pages 2010
The Molecular Chaperone Hsp90 Regulates Accumulation of DNA Polymerase η at Replication Stalling Sites in UV-Irradiated Cells Fulltext Access 11 Pages 2010
A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric Complex Fulltext Access 11 Pages 2010
Decapping Activators in Saccharomyces cerevisiae Act by Multiple Mechanisms Fulltext Access 11 Pages 2010
A Feed-Forward Circuit Controlling Inducible NF-κB Target Gene Activation by Promoter Histone Demethylation Fulltext Access 11 Pages 2010
Recruitment Timing and Dynamics of Transcription Factors at the Hsp70 Loci in Living Cells Fulltext Access 11 Pages 2010
A Transcriptional Activator Is Part of an SCF Ubiquitin Ligase to Control Degradation of Its Cofactors Fulltext Access 11 Pages 2010
Validation of the anisotropy index ellipsoidal area ratio in diffusion tensor imaging Fulltext Access 11 Pages 2010
Neural and vascular variability and the fMRI-BOLD response in normal aging Fulltext Access 11 Pages 2010
Analysis of time reduction methods for magnetic resonance elastography of the brain Fulltext Access 11 Pages 2010
Using NMR Chemical Shifts as Structural Restraints in Molecular Dynamics Simulations of Proteins Fulltext Access 11 Pages 2010
The C-Terminal BAG Domain of BAG5 Induces Conformational Changes of the Hsp70 Nucleotide- Binding Domain for ADP-ATP Exchange Fulltext Access 11 Pages 2010
Allosteric Activation Mechanism of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknB Fulltext Access 11 Pages 2010
A View into the Blind Spot: Solution NMR Provides New Insights into Signal Transduction Across the Lipid Bilayer Fulltext Access 11 Pages 2010
Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain Fulltext Access 11 Pages 2010
Structural Analysis of the RZZ Complex Reveals Common Ancestry with Multisubunit Vesicle Tethering Machinery Fulltext Access 11 Pages 2010
Structural Dynamics of the Magnesium-Bound Conformation of CorA in a Lipid Bilayer Fulltext Access 11 Pages 2010
Structural and Theoretical Studies Indicate that the Cylindrical Protease ClpP Samples Extended and Compact Conformations Fulltext Access 11 Pages 2010
Mapping the Interactions between a Major Pollen Allergen and Human IgE Antibodies Fulltext Access 11 Pages 2010
The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction Fulltext Access 11 Pages 2010
Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4 Fulltext Access 11 Pages 2010
Conserved β-Hairpin Recognition by the GYF Domains of Smy2 and GIGYF2 in mRNA Surveillance and Vesicular Transport Complexes Fulltext Access 11 Pages 2010
Reproducibility of the gadolinium concentration measurements and of the fitting parameters of the vascular input function in the superior sagittal sinus in a patient population Fulltext Access 11 Pages 2010
Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis Fulltext Access 11 Pages 2010
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope Fulltext Access 11 Pages 2010
Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism Fulltext Access 11 Pages 2010
Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation Fulltext Access 11 Pages 2010
HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription Fulltext Access 11 Pages 2010
Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly Fulltext Access 11 Pages 2010
Initiation of the TORC1-Regulated G0 Program Requires Igo1/2, which License Specific mRNAs to Evade Degradation via the 5′-3′ mRNA Decay Pathway Fulltext Access 11 Pages 2010
Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis Fulltext Access 11 Pages 2010
Cdc13 and Telomerase Bind through Different Mechanisms at the Lagging- and Leading-Strand Telomeres Fulltext Access 11 Pages 2010
Noncooperative Interactions between Transcription Factors and Clustered DNA Binding Sites Enable Graded Transcriptional Responses to Environmental Inputs Fulltext Access 11 Pages 2010