Distinguishing between Protein Dynamics and Dye Photophysics in Single-Molecule FRET Experiments Fulltext Access 11 Pages 2010
Thermo- and Mesostabilizing Protein Interactions Identified by Temperature-Dependent Statistical Potentials Fulltext Access 11 Pages 2010
(Un)Folding Mechanisms of the FBP28 WW Domain in Explicit Solvent Revealed by Multiple Rare Event Simulation Methods Fulltext Access 11 Pages 2010
Microarchitecture Is Severely Compromised but Motor Protein Function Is Preserved in Dystrophic mdx Skeletal Muscle Fulltext Access 11 Pages 2010
Synaptotagmin IV Modulation of Vesicle Size and Fusion Pores in PC12 Cells Fulltext Access 11 Pages 2010
NMR Backbone Dynamics of VEK-30 Bound to the Human Plasminogen Kringle 2 Domain Fulltext Access 11 Pages 2010
Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity Fulltext Access 12 Pages 2010
The Extended Conformation of the 2.9-Å Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus Fulltext Access 12 Pages 2010
Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction Fulltext Access 12 Pages 2010
Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling Fulltext Access 12 Pages 2010
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus Fulltext Access 12 Pages 2010
Specific processing of tenascin-C by the metalloprotease meprinβ neutralizes its inhibition of cell spreading Fulltext Access 12 Pages 2010
Dynamic loading stimulates chondrocyte biosynthesis when encapsulated in charged hydrogels prepared from poly(ethylene glycol) and chondroitin sulfate Fulltext Access 12 Pages 2010
Fibrillin-2 is dispensable for peripheral nerve development, myelination and regeneration Fulltext Access 12 Pages 2010
Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes Fulltext Access 12 Pages 2010
Conformational Changes and Ligand Recognition of Escherichia colid-Xylose Binding Protein Revealed Fulltext Access 12 Pages 2010
The Human Breast Cancer Resistance Protein (BCRP/ABCG2) Shows Conformational Changes with Mitoxantrone Fulltext Access 12 Pages 2010
Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway Fulltext Access 12 Pages 2010
ATP-Induced Conformational Dynamics in the AAA+ Motor Unit of Magnesium Chelatase Fulltext Access 12 Pages 2010
Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C Fulltext Access 12 Pages 2010
Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations Fulltext Access 12 Pages 2010
Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism Fulltext Access 12 Pages 2010
Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex Fulltext Access 12 Pages 2010
Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity Fulltext Access 12 Pages 2010
The ARF Tumor Suppressor Controls Ribosome Biogenesis by Regulating the RNA Polymerase I Transcription Factor TTF-I Fulltext Access 12 Pages 2010
Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions Fulltext Access 12 Pages 2010
An experimental model for studying the biomechanics of embryonic tendon: Evidence that the development of mechanical properties depends on the actinomyosin machinery Fulltext Access 12 Pages 2010
Interaction between the extracellular matrix and lymphatics: Consequences for lymphangiogenesis and lymphatic function Fulltext Access 12 Pages 2010
3D segmentation of cell boundaries from whole cell cryogenic electron tomography volumes Fulltext Access 12 Pages 2010
Structural and functional characterisation of the chlorite dismutase from the nitrite-oxidizing bacterium “Candidatus Nitrospira defluvii”: Identification of a catalytically important amino acid residue Fulltext Access 12 Pages 2010
Solution structure and phospho-PmrA recognition mode of PmrD from Klebsiella pneumoniae Fulltext Access 12 Pages 2010
Reprint of: Atmospheric scanning electron microscope observes cells and tissues in open medium through silicon nitride film Fulltext Access 12 Pages 2010
Atmospheric scanning electron microscope observes cells and tissues in open medium through silicon nitride film Fulltext Access 12 Pages 2010
Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB Fulltext Access 12 Pages 2010
Density functional theory analysis and spectral studies on amyloid peptide Aβ(28-35) and its mutants A30G and A30I Fulltext Access 12 Pages 2010
Molecular Mechanisms Modulating Glutamate Kinase Activity. Identification of the Proline Feedback Inhibitor Binding Site Fulltext Access 12 Pages 2010
High-performance iterative electron tomography reconstruction with long-object compensation using graphics processing units (GPUs) Fulltext Access 12 Pages 2010
The spermatogenesis and the sperm structure of Terebrantia (Thysanoptera, Insecta) Fulltext Access 12 Pages 2010
SAXS and X-ray Crystallography Suggest an Unfolding Model for the GDP/GTP Conformational Switch of the Small GTPase Arf6 Fulltext Access 12 Pages 2010
A Novel Intein-Like Autoproteolytic Mechanism in Autotransporter Proteins Fulltext Access 12 Pages 2010
Two Stacked Heme Molecules in the Binding Pocket of the Periplasmic Heme-Binding Protein HmuT from Yersinia pestis Fulltext Access 12 Pages 2010
Probing the Impact of the echinT C-Terminal Domain on Structure and Catalysis Fulltext Access 12 Pages 2010
The Solution Structure of the C-Terminal Ig-like Domain of the Bacteriophage λ Tail Tube Protein Fulltext Access 12 Pages 2010
Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction Fulltext Access 12 Pages 2010
Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells Fulltext Access 12 Pages 2010
The ACF1 Complex Is Required for DNA Double-Strand Break Repair in Human Cells Fulltext Access 12 Pages 2010
3D Cryo-EM Structure of an Active Step I Spliceosome and Localization of Its Catalytic Core Fulltext Access 12 Pages 2010
In silico studies of blood coagulation proteins: from mosaic proteases to nonenzymatic cofactor inhibitors Fulltext Access 12 Pages 2010
Stopped-flow fluorometric study of the interaction of melittin with phospholipid bilayers: importance of the physical state of the bilayer and the acyl chain length Fulltext Access 12 Pages 2010
A Thermodynamic and Structural Study of Myelin Basic Protein in Lipid Membrane Models Fulltext Access 12 Pages 2010
The Dielectric Behavior of Nonspherical Biological Cell Suspensions: An Analytic Approach Fulltext Access 12 Pages 2010
Central Carbon Metabolism as a Minimal Biochemical Walk between Precursors for Biomass and Energy Fulltext Access 12 Pages 2010
In vivo imaging of the human brain at 1.5 T with 0.6-mm isotropic resolution Fulltext Access 12 Pages 2010
Cardiac magnetic resonance imaging using radial k-space sampling and self-calibrated partial parallel reconstruction Fulltext Access 12 Pages 2010
Coupling of simultaneously acquired electrophysiological and haemodynamic responses during visual stimulation Fulltext Access 12 Pages 2010
Denoising 3D MR images by the enhanced non-local means filter for Rician noise Fulltext Access 12 Pages 2010
Synthesis, spectroscopic and mesomorphic studies on heterocyclic liquid crystals with 1,3-oxazepine-4,7-dione, 1,3-oxazepane-4,7-dione and 1,3-oxazepine-1,5-dione cores Fulltext Access 12 Pages 2010
Structure of 6-hydroxy-1-methylquinolinium chloride hydrate studied by X-ray, DFT calculations, FTIR and NMR spectroscopes Fulltext Access 12 Pages 2010
Synthesis, structure, spectroscopic properties, and theoretical studies of alkaline earth metal complexes of 1,3-bis(carboxymethyl)benzimidazolium Fulltext Access 12 Pages 2010
Conformational and structural studies of 2-fluoroethylamine from temperature dependent FT-IR spectra of krypton and xenon solutions and ab initio calculations Fulltext Access 12 Pages 2010
Collaborative Dynamic DNA Scanning by Nucleotide Excision Repair Proteins Investigated by Single- Molecule Imaging of Quantum-Dot-Labeled Proteins Fulltext Access 12 Pages 2010
Invariant U2 snRNA Nucleotides Form a Stem Loop to Recognize the Intron Early in Splicing Fulltext Access 12 Pages 2010
Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2 Fulltext Access 12 Pages 2010
The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration Fulltext Access 12 Pages 2010
Synthesis, spectroscopic characterization and antimicrobial activity of mono-, bi- and tri-nuclear metal complexes of a new Schiff base ligand Fulltext Access 12 Pages 2010
Diverse Pathways Generate MicroRNA-like RNAs and Dicer-Independent Small Interfering RNAs in Fungi Fulltext Access 12 Pages 2010
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination Fulltext Access 12 Pages 2010
SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration Fulltext Access 12 Pages 2010
Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha Fulltext Access 12 Pages 2010
CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability Fulltext Access 12 Pages 2010
A Postincision-Deficient TFIIH Causes Replication Fork Breakage and Uncovers Alternative Rad51- or Pol32-Mediated Restart Mechanisms Fulltext Access 12 Pages 2010
Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions Fulltext Access 12 Pages 2010
Dynamic Control of Yeast MAP Kinase Network by Induced Association and Dissociation between the Ste50 Scaffold and the Opy2 Membrane Anchor Fulltext Access 12 Pages 2010
ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress Fulltext Access 12 Pages 2010
A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation Fulltext Access 12 Pages 2010
CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase Fulltext Access 12 Pages 2010
TMEPAI, a Transmembrane TGF-β-Inducible Protein, Sequesters Smad Proteins from Active Participation in TGF-β Signaling Fulltext Access 12 Pages 2010
Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication Fulltext Access 12 Pages 2010
The Nuclear Poly(A)-Binding Protein Interacts with the Exosome to Promote Synthesis of Noncoding Small Nucleolar RNAs Fulltext Access 12 Pages 2010