K65R and K65A Substitutions in HIV-1 Reverse Transcriptase Enhance Polymerase Fidelity by Decreasing Both dNTP Misinsertion and Mispaired Primer Extension Efficiencies Fulltext Access 12 Pages 2010
APOBEC1 and APOBEC3 Cytidine Deaminases as Restriction Factors for Hepadnaviral Genomes in Non-Humans In Vivo Fulltext Access 12 Pages 2010
Time-Dependent Changes in Side-Chain Solvent Accessibility during Cytochrome c Folding Probed by Pulsed Oxidative Labeling and Mass Spectrometry Fulltext Access 12 Pages 2010
Disulfide-Reduced ALS Variants of Cu, Zn Superoxide Dismutase Exhibit Increased Populations of Unfolded Species Fulltext Access 12 Pages 2010
Conformational Plasticity of the Coiled-Coil Domain of BmrR Is Required for bmr Operator Binding: The Structure of Unliganded BmrR Fulltext Access 12 Pages 2010
Heterocyst-Specific Transcription of NsiR1, a Non-Coding RNA Encoded in a Tandem Array of Direct Repeats in Cyanobacteria Fulltext Access 12 Pages 2010
An Archaeal Dim2-Like Protein, aDim2p, Forms a Ternary Complex with a/eIF2α and the 3′ End Fragment of 16S rRNA Fulltext Access 12 Pages 2010
Crystal Structure of the Leucine Aminopeptidase from Pseudomonas putida Reveals the Molecular Basis for its Enantioselectivity and Broad Substrate Specificity Fulltext Access 12 Pages 2010
Identification of an Allosteric Signaling Network within Tec Family Kinases Fulltext Access 12 Pages 2010
Distinct Regions of Human eIF3 Are Sufficient for Binding to the HCV IRES and the 40S Ribosomal Subunit Fulltext Access 12 Pages 2010
Correlation between the OmpG Secondary Structure and Its pH-Dependent Alterations Monitored by FTIR Fulltext Access 12 Pages 2010
The Sulfated Triphenyl Methane Derivative Acid Fuchsin Is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation Fulltext Access 12 Pages 2010
Orientation of Small Multidrug Resistance Transporter Subunits in the Membrane: Correlation with the Positive-Inside Rule Fulltext Access 12 Pages 2010
Mutations within the S4–S5 Linker Alter Voltage Sensor Constraints in hERG K+ Channels Fulltext Access 12 Pages 2010
Transcription of mouse Sp2 yields alternatively spliced and sub-genomic mRNAs in a tissue- and cell-type-specific fashion Fulltext Access 12 Pages 2010
Massive translational repression of gene expression during mouse erythroid differentiation Fulltext Access 12 Pages 2010
Small molecules from natural sources, targeting signaling pathways in diabetes Fulltext Access 12 Pages 2010
Molecular Basis for the High Degree of Antigenic Cross-Reactivity between Hepatitis B Virus Capsids (HBcAg) and Dimeric Capsid-Related Protein (HBeAg): Insights into the Enigmatic Nature of the e-Antigen Fulltext Access 12 Pages 2010
RCC1 Uses a Conformationally Diverse Loop Region to Interact with the Nucleosome: A Model for the RCC1–Nucleosome Complex Fulltext Access 12 Pages 2010
Characterization of Inhibitor-Bound α-Synuclein Dimer: Role of α-Synuclein N-Terminal Region in Dimerization and Inhibitor Binding Fulltext Access 12 Pages 2010
Control of Substrate Gating and Translocation into ClpP by Channel Residues and ClpX Binding Fulltext Access 12 Pages 2010
Exploring the Linkage Dependence of Polyubiquitin Conformations Using Molecular Modeling Fulltext Access 12 Pages 2010
Identifying Assembly-Inhibiting and Assembly-Tolerant Sites in the SbsB S-Layer Protein from Geobacillus stearothermophilus Fulltext Access 12 Pages 2010
Folding of Tetrameric p53: Oligomerization and Tumorigenic Mutations Induce Misfolding and Loss of Function Fulltext Access 12 Pages 2010
Directed Evolution of an Enhanced and Highly Efficient FokI Cleavage Domain for Zinc Finger Nucleases Fulltext Access 12 Pages 2010
The Bacteriophage Genome Undergoes a Succession of Intracapsid Phase Transitions upon DNA Ejection Fulltext Access 12 Pages 2010
Vasculogenesis and angiogenesis in the endometrium during menstrual cycle and implantation Fulltext Access 12 Pages 2010
Crystal Structure of Mouse Elf3 C-terminal DNA-binding Domain in Complex with Type II TGF-β Receptor Promoter DNA Fulltext Access 12 Pages 2010
Repositioning of Transmembrane α-Helices during Membrane Protein Folding Fulltext Access 12 Pages 2010
RNA Polymerase II and TAFs Undergo a Slow Isomerization after the Polymerase Is Recruited to Promoter-Bound TFIID Fulltext Access 12 Pages 2010
Human Positive Coactivator 4 Controls Heterochromatinization and Silencing of Neural Gene Expression by Interacting with REST/NRSF and CoREST Fulltext Access 12 Pages 2010
Single-Molecule Study of DNA Polymerization Activity of HIV-1 Reverse Transcriptase on DNA Templates Fulltext Access 12 Pages 2010
Structural and Biophysical Studies of Human PARP-1 in Complex with Damaged DNA Fulltext Access 12 Pages 2010
The Baseplate Wedges of Bacteriophage T4 Spontaneously Assemble into Hubless Baseplate-Like Structure In Vitro Fulltext Access 12 Pages 2010
Transcription Profile of Thermus thermophilus CRISPR Systems after Phage Infection Fulltext Access 12 Pages 2010
Structure of Avian Thymic Hormone, a High-Affinity Avian β-Parvalbumin, in the Ca2+-Free and Ca2+-Bound States Fulltext Access 12 Pages 2010
Characterization of a Discontinuous Epitope of the HIV Envelope Protein gp120 Recognized by a Human Monoclonal Antibody Using Chemical Modification and Mass Spectrometric Analysis Fulltext Access 12 Pages 2010
New Advances in the Understanding of the In-Source Decay Fragmentation of Peptides in MALDI-TOF-MS Fulltext Access 12 Pages 2010
A Method for Comprehensive Analysis of Urinary Acylglycines by Using Ultra-Performance Liquid Chromatography Quadrupole Linear Ion Trap Mass Spectrometry Fulltext Access 12 Pages 2010
HPLC/APCI-FTICR-MS as a Tool for Identification of Partial Polar Mutagenic Compounds in Effect-Directed Analysis Fulltext Access 12 Pages 2010
Top-Down Mass Spectrometry for Sequencing of Larger (up to 61 nt) RNA by CAD and EDD Fulltext Access 12 Pages 2010
Targeted Data Acquisition for Improved Reproducibility and Robustness of Proteomic Mass Spectrometry Assays Fulltext Access 12 Pages 2010
Gas-Phase Acidities of Cysteine-Polyglycine Peptides: The Effect of the Cysteine Position Fulltext Access 12 Pages 2010
Infrared Multiphoton Dissociation of Small-Interfering RNA Anions and Cations Fulltext Access 12 Pages 2010
Amino Acid Influence on Copper Binding to Peptides: Cysteine Versus Arginine Fulltext Access 12 Pages 2010
Identification and Counting of Carbonyl and Hydroxyl Functionalities in Protonated Bifunctional Analytes by Using Solution Derivatization Prior to Mass Spectrometric Analysis Via Ion-Molecule Reactions Fulltext Access 12 Pages 2010
Fine grained sampling of residue characteristics using molecular dynamics simulation Fulltext Access 12 Pages 2010
Copper(II) and zinc(II) complexes with macrocyclic ligand: Structure variation via counteranion and co-ligand Fulltext Access 12 Pages 2010
Proteomic profiling during atherosclerosis progression using SELDI-TOF-MS: Effect of darbepoetin treatment Fulltext Access 12 Pages 2010
Extracellular signal-regulated kinase and phosphatidylinositol-3-kinase/AKT signalling pathways in the human carotid body and peripheral ganglia Fulltext Access 12 Pages 2010
Peptidyl arginine deiminase: A novel immunohistochemical marker for liver fibrosis in patients with chronic hepatitis Fulltext Access 12 Pages 2010
Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex Fulltext Access 12 Pages 2010
The Molecular Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis Bound to Ornithine, a Competitive Inhibitor Fulltext Access 12 Pages 2010
Supramolecular assemblies of single-substituted nitrobenzenes in their experimental and predicted crystal structures Fulltext Access 12 Pages 2010
Gas-Phase Meerwein Reaction of Epoxides with Protonated Acetonitrile Generated by Atmospheric Pressure Ionizations Fulltext Access 12 Pages 2010
Microstructure characterization and thermal analysis of hybrid block copolymer α-methoxy-poly(ethylene glycol)-block-poly[ε-(benzyloxycarbonyl)-l-lysine] for biomedical applications Fulltext Access 12 Pages 2010
H/D Exchange Kinetics: Experimental Evidence for Formation of Different b Fragment Ion Conformers/Isomers During the Gas-Phase Peptide Sequencing Fulltext Access 12 Pages 2010
Synthesis, crystal structures and magnetic properties of a new radical NIT-1′-MeBzIm and the corresponding complexes of Ni(II), Co(II) and Zn(II) containing NIT-1′-MeBzIm Fulltext Access 12 Pages 2010
Mapping N-Terminus Phosphorylation Sites and Quantitation by Stable Isotope Dimethyl Labeling Fulltext Access 12 Pages 2010
Microwave, infrared, and Raman spectra, r0 structural parameters, conformational stability, and vibrational assignment of ethynylcyclohexane Fulltext Access 12 Pages 2010
A gas-phase electron diffraction and quantum chemical investigation of the molecular structure of 1-bromosilacyclobutane Fulltext Access 12 Pages 2010
Influence of chlorine substitution on intramolecular hydrogen bond energy and ESIPT barrier: Experimental and theoretical measurements on the photophysics of 3,5-dichlorosalicylic acid Fulltext Access 12 Pages 2010
FT-IR, FT-Raman, NMR spectral analysis and theoretical NBO, HOMO–LUMO analysis of bis(4-amino-5-mercapto-1,2,4-triazol-3-yl)ethane by ab initio HF and DFT methods Fulltext Access 12 Pages 2010
Dynamics of silica cell wall morphogenesis in the diatom Cyclotella cryptica: Substructure formation and the role of microfilaments Fulltext Access 13 Pages 2010
Biophysical characterization of recombinant proteins: A key to higher structural genomics success Fulltext Access 13 Pages 2010
Modulation of G-protein coupled receptor sample quality by modified cell-free expression protocols: A case study of the human endothelin A receptor Fulltext Access 13 Pages 2010
The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium Fulltext Access 13 Pages 2010
Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-ray diffraction and small-angle X-ray scattering Fulltext Access 13 Pages 2010
Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s Fulltext Access 13 Pages 2010
Probabilistic principal component analysis with expectation maximization (PPCA-EM) facilitates volume classification and estimates the missing data Fulltext Access 13 Pages 2010
Magnetic resonance image enhancement using stochastic resonance in Fourier domain Fulltext Access 13 Pages 2010
Spin-echo SS-PARSE: a PARSE MRI method to estimate frequency, R2 and R2â² in a single shot Fulltext Access 13 Pages 2010
Effects of Supercharging Reagents on Noncovalent Complex Structure in Electrospray Ionization from Aqueous Solutions Fulltext Access 13 Pages 2010
Multifactorial Analysis of Affinity-Mass Spectrometry Data from Serum Protein Samples: A Strategy to Distinguish Patients with Preeclampsia from Matching Control Individuals Fulltext Access 13 Pages 2010
Relative, Label-free Protein Quantitation: Spectral Counting Error Statistics from Nine Replicate MudPIT Samples Fulltext Access 13 Pages 2010
Electrospray Ionization Multiple-Stage Linear Ion-trap Mass Spectrometry for Structural Elucidation of Triacylglycerols: Assignment of Fatty Acyl Groups on the Glycerol Backbone and Location of Double Bonds Fulltext Access 13 Pages 2010
Desorption Electrospray Ionization Imaging Mass Spectrometry of Lipids in Rat Spinal Cord Fulltext Access 13 Pages 2010
UV-MALDI-TOF Mass Spectrometry Analysis of Heparin Oligosaccharides Obtained by Nitrous Acid Controlled Degradation and High Performance Anion Exchange Chromatography Fulltext Access 13 Pages 2010
Resolving the Composition of Protein Complexes Using a MALDI LTQ Orbitrap Fulltext Access 13 Pages 2010
Ion Spectroscopy: Where Did It Come From; Where Is It Now; and Where Is It Going? Fulltext Access 13 Pages 2010
ESI-MS Differential Fragmentation of Positional Isomers of Sulfated Oligosaccharides Derived from Carrageenans and Agarans Fulltext Access 13 Pages 2010
‘Fixed Charge' Chemical Derivatization and Data Dependant Multistage Tandem Mass Spectrometry for Mapping Protein Surface Residue Accessibility Fulltext Access 13 Pages 2010