Mutations in the C. elegans Succinate Dehydrogenase Iron–Sulfur Subunit Promote Superoxide Generation and Premature Aging Fulltext Access 11 Pages 2009
Binding Hot Spot in the Weak Protein Complex of Physiological Redox Partners Yeast Cytochrome c and Cytochrome c Peroxidase Fulltext Access 11 Pages 2009
A Structural Basis for the Recognition of 2′-Deoxyguanosine by the Purine Riboswitch Fulltext Access 11 Pages 2009
Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3 Fulltext Access 11 Pages 2009
Selecting Optimum Eukaryotic Integral Membrane Proteins for Structure Determination by Rapid Expression and Solubilization Screening Fulltext Access 11 Pages 2009
DNA Double-Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases Fulltext Access 11 Pages 2009
Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors Fulltext Access 11 Pages 2009
Crystal Structure of Bacillus cereusd-Alanyl Carrier Protein Ligase (DltA) in Complex with ATP Fulltext Access 11 Pages 2009
Charged Amino Acids in a Preprotein Inhibit SecA-Dependent Protein Translocation Fulltext Access 11 Pages 2009
Cryo-electron Microscopy of the Vacuolar ATPase Motor Reveals its Mechanical and Regulatory Complexity Fulltext Access 11 Pages 2009
Structural Analysis of BldR from Sulfolobus solfataricus Provides Insights into the Molecular Basis of Transcriptional Activation in Archaea by MarR Family Proteins Fulltext Access 11 Pages 2009
Structural Characterization of Clostridium acetobutylicum 8-Oxoguanine DNA Glycosylase in Its Apo Form and in Complex with 8-Oxodeoxyguanosine Fulltext Access 11 Pages 2009
Differential Stability of High-density Lipoprotein Subclasses: Effects of Particle Size and Protein Composition Fulltext Access 11 Pages 2009
The Sequence Dependence of Human Nucleotide Excision Repair Efficiencies of Benzo[a]pyrene-derived DNA Lesions: Insights into the Structural Factors that Favor Dual Incisions Fulltext Access 11 Pages 2009
Human Immunoglobulin Repertoires against Tetanus Toxoid Contain a Large and Diverse Fraction of High-Affinity Promiscuous VH Genes Fulltext Access 11 Pages 2009
Dynamic Regulatory Interactions of Rad51, Rad52, and Replication Protein-A in Recombination Intermediates Fulltext Access 11 Pages 2009
NMR Solution Structure of SlyD from Escherichia coli: Spatial Separation of Prolyl Isomerase and Chaperone Function Fulltext Access 11 Pages 2009
The Calcium-Dependent and Calcium-Independent Membrane Binding of Synaptotagmin 1: Two Modes of C2B Binding Fulltext Access 11 Pages 2009
Respiratory Complexes III and IV Are Not Essential for the Assembly/Stability of Complex I in Fungi Fulltext Access 11 Pages 2009
Desmin and Vimentin Intermediate Filament Networks: Their Viscoelastic Properties Investigated by Mechanical Rheometry Fulltext Access 11 Pages 2009
Contributions of the Transmembrane Domain and a Key Acidic Motif to Assembly and Function of the TatA Complex Fulltext Access 11 Pages 2009
The Crystal Structure of the Pseudomonas dacunhae Aspartate-β-Decarboxylase Dodecamer Reveals an Unknown Oligomeric Assembly for a Pyridoxal-5′-Phosphate-Dependent Enzyme Fulltext Access 11 Pages 2009
Structural Interpretation of Paramagnetic Relaxation Enhancement-Derived Distances for Disordered Protein States Fulltext Access 11 Pages 2009
Structural Mechanisms of Inactivation in Scabies Mite Serine Protease Paralogues Fulltext Access 11 Pages 2009
Selective Detection of Specific Protein-Ligand Complexes by Electrosonic Spray-Precursor Ion Scan Tandem Mass Spectrometry Fulltext Access 11 Pages 2009
Measurement of Neuropeptides in Crustacean Hemolymph via MALDI Mass Spectrometry Fulltext Access 11 Pages 2009
A Mass Spectrometry Study of Alkanes in Air Plasma at Atmospheric Pressure Fulltext Access 11 Pages 2009
Cryoelectron Microscopy Structure of Purified γ-Secretase at 12 Å Resolution Fulltext Access 11 Pages 2009
Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding Fulltext Access 11 Pages 2009
Crystal Structure of the Pml1p Subunit of the Yeast Precursor mRNA Retention and Splicing Complex Fulltext Access 11 Pages 2009
Structure and Action of the Myxobacterial Chondrochloren Halogenase CndH: A New Variant of FAD-dependent Halogenases Fulltext Access 11 Pages 2009
Evidence for a Tyrosine–Adenine Stacking Interaction and for a Short-lived Open Intermediate Subsequent to Initial Binding of Escherichia coli RNA Polymerase to Promoter DNA Fulltext Access 11 Pages 2009
Conformational Conversion May Precede or Follow Aggregate Elongation on Alternative Pathways of Amyloid Protofibril Formation Fulltext Access 11 Pages 2009
X-Ray Fluorescence Microscopy Reveals the Role of Selenium in Spermatogenesis Fulltext Access 11 Pages 2009
A Novel Main Chain Motif in Proteins Bridged by Cationic Groups: The Niche Fulltext Access 11 Pages 2009
Mammalian OS-9 Is Upregulated in Response to Endoplasmic Reticulum Stress and Facilitates Ubiquitination of Misfolded Glycoproteins Fulltext Access 11 Pages 2009
Characterization of Oligomeric Species on the Aggregation Pathway of Human Lysozyme Fulltext Access 11 Pages 2009
Infectious Bursal Disease Virus: Ribonucleoprotein Complexes of a Double-Stranded RNA Virus Fulltext Access 11 Pages 2009
Purified Membrane-Containing Procapsids of Bacteriophage PRD1 Package the Viral Genome Fulltext Access 11 Pages 2009
Nucleotide-Induced Flexibility Change in Neck Linkers of Dimeric Kinesin as Detected by Distance Measurements Using Spin-Labeling EPR Fulltext Access 11 Pages 2009
The Supramolecular Organization of the C. elegans Nuclear Lamin Filament Fulltext Access 11 Pages 2009
Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15 Fulltext Access 11 Pages 2009
Oligomeric-State-Dependent Conformational Change of the BLUF Protein TePixD (Tll0078) Fulltext Access 11 Pages 2009
Structural Characterization of the As/Sb Reductase LmACR2 from Leishmania major Fulltext Access 11 Pages 2009
Origin of Supercharging in Electrospray Ionization of Noncovalent Complexes from Aqueous Solution Fulltext Access 11 Pages 2009
Myosin VI Dimerization Triggers an Unfolding of a Three-Helix Bundle in Order to Extend Its Reach Fulltext Access 11 Pages 2009
Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13 Fulltext Access 11 Pages 2009
Characterization of Cytoplasmic Caspase-2 Activation by Induced Proximity Fulltext Access 11 Pages 2009
Eukaryotic Initiation Factor 4a3 Is a Selenium-Regulated RNA-Binding Protein that Selectively Inhibits Selenocysteine Incorporation Fulltext Access 11 Pages 2009
A Reciprocal Interdependence between Nck and PI(4,5)P2 Promotes Localized N-WASp-Mediated Actin Polymerization in Living Cells Fulltext Access 11 Pages 2009
Microwave spectra, r0 structural parameters, and conformational stability from xenon solutions of silylcyclohexane Fulltext Access 11 Pages 2009
Shifting Unoccupied Spectral Space in Mass Spectrum of Peptide Fragment Ions Fulltext Access 11 Pages 2009
Comparison of Ion Coupling Strategies for a Microengineered Quadrupole Mass Filter Fulltext Access 11 Pages 2009
A Simple Model for the Disintegration of Highly Charged Solvent Droplets during Electrospray Ionization Fulltext Access 11 Pages 2009
Femtosecond Laser Photoionization Time-of-Flight Mass Spectrometry of Nitro-aromatic Explosives and Explosives Related Compounds Fulltext Access 11 Pages 2009
Gas-Phase Interactions Between Lead(II) Ions and Thiouracil Nucleobases: A Combined Experimental and Theoretical Study Fulltext Access 11 Pages 2009
TACE-Mediated Ectodomain Shedding of the Type I TGF-β Receptor Downregulates TGF-β Signaling Fulltext Access 11 Pages 2009
Towards a Second Generation of Ionic Liquid Matrices (ILMs) for MALDI-MS of Peptides, Proteins, and Carbohydrates Fulltext Access 11 Pages 2009
Electron Capture Dissociation Product Ion Abundances at the X Amino Acid in RAAAA-X-AAAAK Peptides Correlate with Amino Acid Polarity and Radical Stability Fulltext Access 11 Pages 2009
Multiple-Reaction Monitoring Liquid Chromatography Mass Spectrometry for Monosaccharide Compositional Analysis of Glycoproteins Fulltext Access 11 Pages 2009
Periodic Sequence Distribution of Product Ion Abundances in Electron Capture Dissociation of Amphipathic Peptides and Proteins Fulltext Access 11 Pages 2009
Tracking Radical Migration in Large Hydrogen Deficient Peptides with Covalent Labels: Facile Movement does not Equal Indiscriminate Fragmentation Fulltext Access 11 Pages 2009
Comparison Between Vacuum Sublimed Matrices and Conventional Dried Droplet Preparation in MALDI-TOF Mass Spectrometry Fulltext Access 11 Pages 2009
The Renaissance of High-Energy CID for Structural Elucidation of Complex Lipids: MALDI-TOF/RTOF-MS of Alkali Cationized Triacylglycerols Fulltext Access 11 Pages 2009
Gas-Phase Fragmentation of Long-Lived Cysteine Radical Cations Formed Via NO Loss from Protonated S-Nitrosocysteine⁎† Fulltext Access 11 Pages 2009
Fragmentation Pathways of Polycyclic Polyisoprenylated Benzophenones and Degradation Profile of Nemorosone by Multiple-Stage Tandem Mass Spectrometry Fulltext Access 11 Pages 2009
Hybrid stochastic simulations of intracellular reaction–diffusion systems Fulltext Access 11 Pages 2009
A virtual screening study of the acetylcholine binding protein using a relaxed–complex approach Fulltext Access 11 Pages 2009
Insights into Branch Nucleophile Positioning and Activation from an Orthogonal Pre-mRNA Splicing System in Yeast Fulltext Access 11 Pages 2009
E46K Parkinson’s-Linked Mutation Enhances C-Terminal-to-N-Terminal Contacts in α-Synuclein Fulltext Access 11 Pages 2009
The Folding Trajectory of RNase H Is Dominated by Its Topology and Not Local Stability: A Protein Engineering Study of Variants that Fold via Two-State and Three-State Mechanisms Fulltext Access 11 Pages 2009
Modulation of Calmodulin Plasticity by the Effect of Macromolecular Crowding Fulltext Access 11 Pages 2009
Crystal Structure of the Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex—Implications for Clamp Loading and Regulation Fulltext Access 11 Pages 2009
Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response Fulltext Access 11 Pages 2009
The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain Fulltext Access 11 Pages 2009
Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3 Fulltext Access 11 Pages 2009
The Effect of Replication Initiation on Gene Amplification in the rDNA and Its Relationship to Aging Fulltext Access 11 Pages 2009
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome Fulltext Access 11 Pages 2009
Coronin Switches Roles in Actin Disassembly Depending on the Nucleotide State of Actin Fulltext Access 11 Pages 2009
SPORCalc: A development of a database analysis that provides putative metabolic enzyme reactions for ligand-based drug design Fulltext Access 11 Pages 2009
A Core Complex of CPSF73, CPSF100, and Symplekin May Form Two Different Cleavage Factors for Processing of Poly(A) and Histone mRNAs Fulltext Access 11 Pages 2009
Distinct Targets of the Eco1 Acetyltransferase Modulate Cohesion in S Phase and in Response to DNA Damage Fulltext Access 11 Pages 2009
Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2 Fulltext Access 11 Pages 2009
The Plasticity of a Translation Arrest Motif Yields Insights into Nascent Polypeptide Recognition inside the Ribosome Tunnel Fulltext Access 11 Pages 2009
Rtr1 Is a CTD Phosphatase that Regulates RNA Polymerase II during the Transition from Serine 5 to Serine 2 Phosphorylation Fulltext Access 11 Pages 2009
Polo Kinase Regulates Mitotic Chromosome Condensation by Hyperactivation of Condensin DNA Supercoiling Activity Fulltext Access 11 Pages 2009
FACT and Asf1 Regulate Nucleosome Dynamics and Coactivator Binding at the HO Promoter Fulltext Access 11 Pages 2009
Srs2 Disassembles Rad51 Filaments by a Protein-Protein Interaction Triggering ATP Turnover and Dissociation of Rad51 from DNA Fulltext Access 11 Pages 2009
GTP Hydrolysis by IF2 Guides Progression of the Ribosome into Elongation Fulltext Access 11 Pages 2009