Three-dimensional Structures of Fibrillar Sm Proteins: Hfq and Other Sm-like Proteins Fulltext Access 11 Pages 2006
Recapitulation and Design of Protein Binding Peptide Structures and Sequences Fulltext Access 11 Pages 2006
An Atomic Model of the Thin Filament in the Relaxed and Ca2+-Activated States Fulltext Access 11 Pages 2006
How Evolutionary Pressure Against Protein Aggregation Shaped Chaperone Specificity Fulltext Access 11 Pages 2006
Functional Analysis of the Post-transcriptional Regulator RsmA Reveals a Novel RNA-binding Site Fulltext Access 11 Pages 2006
Unassisted Membrane Insertion as the Initial Step in ΔpH/Tat-dependent Protein Transport Fulltext Access 11 Pages 2006
Single Proline Residues can Dictate the Oxidative Folding Pathways of Cysteine-rich Peptides Fulltext Access 11 Pages 2006
Crystal Structures of Archaerhodopsin-1 and -2: Common Structural Motif in Archaeal Light-driven Proton Pumps Fulltext Access 11 Pages 2006
The Arabidopsis Genome Encodes Structurally and Functionally Diverse HMGB-type Proteins Fulltext Access 11 Pages 2006
Structural Basis for the Cooperative Assembly of Large T Antigen on the Origin of Replication Fulltext Access 11 Pages 2006
Structural Basis for Domain–Domain Communication in a Protein Tyrosine Kinase, the C-terminal Src Kinase Fulltext Access 11 Pages 2006
The Allosteric Mechanism of Yeast Chorismate Mutase: A Dynamic Analysis Fulltext Access 11 Pages 2006
Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design Fulltext Access 11 Pages 2006
Folding Transitions During Assembly of the Eukaryotic mRNA Cap-binding Complex Fulltext Access 11 Pages 2006
Thermal Adaptation of the Yeast Mitochondrial Hsp70 System is Regulated by the Reversible Unfolding of its Nucleotide Exchange Factor Fulltext Access 11 Pages 2006
The Dimerization Mechanism of LIS1 and its Implication for Proteins Containing the LisH Motif Fulltext Access 11 Pages 2006
Crystal Structures of Yersinia enterocolitica Salicylate Synthase and its Complex with the Reaction Products Salicylate and Pyruvate Fulltext Access 11 Pages 2006
Structure of the Regulatory Apparatus of a Calcium-dependent Protein Kinase (CDPK): A Novel Mode of Calmodulin-target Recognition Fulltext Access 11 Pages 2006
Interactions in Native Binding Sites Cause a Large Change in Protein Dynamics Fulltext Access 11 Pages 2006
Interactions of RadB, a DNA Repair Protein in Archaea, with DNA and ATP Fulltext Access 11 Pages 2006
Sequence Alignment and Homology Threading Reveals Prokaryotic and Eukaryotic Proteins Similar to Lactose Permease Fulltext Access 11 Pages 2006
The Crystal Structure of 5′-Deoxy-5′-methylthioadenosine Phosphorylase II from Sulfolobus solfataricus, a Thermophilic Enzyme Stabilized by Intramolecular Disulfide Bonds Fulltext Access 11 Pages 2006
What Limits the Velocity of Fast-skeletal Muscle Contraction in Mammals? Fulltext Access 11 Pages 2006
Structure of the Escherichia coli FlhDC Complex, a Prokaryotic Heteromeric Regulator of Transcription Fulltext Access 11 Pages 2006
Designing Thermostable Proteins: Ancestral Mutants of 3-Isopropylmalate Dehydrogenase Designed by using a Phylogenetic Tree Fulltext Access 11 Pages 2006
Characterizing Molecular Interactions in Different Bacteriorhodopsin Assemblies by Single-molecule Force Spectroscopy Fulltext Access 11 Pages 2006
The Transition State for Folding of a Peripheral Subunit-binding Domain Contains Robust and Ionic-strength Dependent Characteristics Fulltext Access 11 Pages 2006
Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu–Zn, Zn–Zn and As-isolated Wild-type Enzymes Fulltext Access 11 Pages 2006
Structural Dynamics of the Actin–Myosin Interface by Site-directed Spectroscopy Fulltext Access 11 Pages 2006
Structural Analyses of Sum1-1p-dependent Transcriptionally Silent Chromatin in Saccharomyces cerevisiae Fulltext Access 11 Pages 2006
Contribution of Electrostatic Interactions, Compactness and Quaternary Structure to Protein Thermostability: Lessons from Structural Genomics of Thermotoga maritima Fulltext Access 11 Pages 2006
Structure of the Dodecahedral Penton Particle from Human Adenovirus Type 3 Fulltext Access 11 Pages 2006
Modulator of Drug Activity B from Escherichia coli: Crystal Structure of a Prokaryotic Homologue of DT-diaphorase Fulltext Access 11 Pages 2006
Crystal Structure of the Polyketide Cyclase AknH with Bound Substrate and Product Analogue: Implications for Catalytic Mechanism and Product Stereoselectivity Fulltext Access 11 Pages 2006
Alternate Interfaces May Mediate Homomeric and Heteromeric Assembly in the Transmembrane Domains of SNARE Proteins Fulltext Access 11 Pages 2006
Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP–DNA Complex: Recognition of Pyrimidine-Purine and Purine-Purine Steps Fulltext Access 11 Pages 2006
Structural Insights into the Cryptic DNA-dependent ATPase Activity of UvrB Fulltext Access 11 Pages 2006
High Plasticity of the Hepatitis B Virus Capsid Revealed by Conformational Stress Fulltext Access 11 Pages 2006
Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens Fulltext Access 11 Pages 2006
Interaction of gp16 with pRNA and DNA for Genome Packaging by the Motor of Bacterial Virus phi29 Fulltext Access 11 Pages 2006
Kinetic Computational Alanine Scanning: Application to p53 Oligomerization Fulltext Access 11 Pages 2006
A Conserved Base-pair between tRNA and 23 S rRNA in the Peptidyl Transferase Center Is Important for Peptide Release Fulltext Access 11 Pages 2006
Asp302 Determines Potassium Dependence of a RadA Recombinase from Methanococcus voltae Fulltext Access 11 Pages 2006
The Crystal Structure of the Transthyretin-like Protein from Salmonella dublin, a Prokaryote 5-Hydroxyisourate Hydrolase Fulltext Access 11 Pages 2006
Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis Fulltext Access 11 Pages 2006
Hydrogen Bonding Markedly Reduces the pK of Buried Carboxyl Groups in Proteins Fulltext Access 11 Pages 2006
Structure of a Hyper-cleavable Monomeric Fragment of Phage λ Repressor Containing the Cleavage Site Region Fulltext Access 11 Pages 2006
Opening of Holes in Liposomal Membranes Is Induced by Proteins Possessing the FERM Domain Fulltext Access 11 Pages 2006
Rapid Kinetics of Protein–Nucleic Acid Interaction is a Major Component of HIV-1 Nucleocapsid Protein’s Nucleic Acid Chaperone Function Fulltext Access 11 Pages 2006
The Evolution of Catalytic Efficiency and Substrate Promiscuity in Human Theta Class 1-1 Glutathione Transferase Fulltext Access 11 Pages 2006
Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer Fulltext Access 11 Pages 2006
A Mutation in the S-switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for CBFβ Regulation Fulltext Access 11 Pages 2006
Recognition and Positioning of mRNA in the Ribosome by tRNAs with Expanded Anticodons Fulltext Access 11 Pages 2006
Physical and Functional Interactions between the Prostate Suppressor Homeoprotein NKX3.1 and Serum Response Factor Fulltext Access 11 Pages 2006
The UAA/GAN Internal Loop Motif: A New RNA Structural Element that Forms a Cross-strand AAA Stack and Long-range Tertiary Interactions Fulltext Access 11 Pages 2006
Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis Fulltext Access 11 Pages 2006
Arylamine N-acetyltransferase Aggregation and Constitutive Ubiquitylation Fulltext Access 11 Pages 2006
Energetics and Kinetics of Cooperative Cofilin–Actin Filament Interactions Fulltext Access 11 Pages 2006
Structural Differences in Aβ Amyloid Protofibrils and Fibrils Mapped by Hydrogen Exchange – Mass Spectrometry with On-line Proteolytic Fragmentation Fulltext Access 11 Pages 2006
From Monomeric to Homodimeric Endonucleases and Back: Engineering Novel Specificity of LAGLIDADG Enzymes Fulltext Access 11 Pages 2006
Structure-based Stability Engineering of the Mouse IgG1 Fab Fragment by Modifying Constant Domains Fulltext Access 11 Pages 2006
Chimeric Fc Receptors Identify Ligand Binding Regions in Human Glycoprotein VI Fulltext Access 11 Pages 2006
Identification of Two Interaction Sites in SecY that Are Important for the Functional Interaction with SecA Fulltext Access 11 Pages 2006
Chain Length-dependent Binding of Fatty Acid Anions to Human Serum Albumin Studied by Site-directed Mutagenesis Fulltext Access 11 Pages 2006
Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases Fulltext Access 11 Pages 2006
Unique Regulation of the Active site of the Serine Esterase S-Formylglutathione Hydrolase Fulltext Access 11 Pages 2006
The Crystal Structure of a Plant 3-Ketoacyl-CoA Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid β-Oxidation Fulltext Access 11 Pages 2006
Structure and Reaction Mechanism of l-Rhamnulose Kinase from Escherichia coli Fulltext Access 11 Pages 2006
New Roles for Key Residues in Helices H1 and H2 of the Escherichia coli H-NS N-terminal Domain: H-NS Dimer Stabilization and Hha Binding Fulltext Access 11 Pages 2006
Nudged Elastic Band Calculation of Minimal Energy Paths for the Conformational Change of a GG Non-canonical Pair Fulltext Access 11 Pages 2006
Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin Fulltext Access 11 Pages 2006
Three-dimensional Crystal Structure and Enzymic Characterization of β-Mannanase Man5A from Blue Mussel Mytilus edulis Fulltext Access 11 Pages 2006
Crystal Structure of Neoculin: Insights into its Sweetness and Taste-modifying Activity Fulltext Access 11 Pages 2006
Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase Fulltext Access 11 Pages 2006
Microsecond Dynamics of Protein–DNA Interactions: Direct Observation of the Wrapping/Unwrapping Kinetics of Single-stranded DNA around the E. coli SSB Tetramer Fulltext Access 11 Pages 2006
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP Fulltext Access 11 Pages 2006
A Large Domain Swap in the VirB11 ATPase of Brucella suis Leaves the Hexameric Assembly Intact Fulltext Access 11 Pages 2006
Membrane-transferring Sequences of the HIV-1 Gp41 Ectodomain Assemble into an Immunogenic Complex Fulltext Access 11 Pages 2006
Seeding-dependent Propagation and Maturation of β2-Microglobulin Amyloid Fibrils Under High Pressure Fulltext Access 11 Pages 2006
Common Motifs and Topological Effects in the Protein Folding Transition State Fulltext Access 11 Pages 2006
Sterol Regulatory Element-binding Protein-2 Negatively Regulates Low Density Lipoprotein Receptor-related Protein Transcription Fulltext Access 11 Pages 2006
The 2.1 Å Crystal Structure of copGFP, a Representative Member of the Copepod Clade Within the Green Fluorescent Protein Superfamily Fulltext Access 11 Pages 2006
The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein Fulltext Access 11 Pages 2006
Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism Fulltext Access 11 Pages 2006