Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH Fulltext Access 11 Pages 2005
Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom Fulltext Access 11 Pages 2005
Crystal structure of a novel phospholipase A2 from Naja naja sagittifera with a strong anticoagulant activity Fulltext Access 11 Pages 2005
The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination Fulltext Access 11 Pages 2005
P element excision and repair by non-homologous end joining occurs in both G1 and G2 of the cell cycle Fulltext Access 11 Pages 2005
Accelerated aging pathology in ad libitum fed XpdTTD mice is accompanied by features suggestive of caloric restriction Fulltext Access 11 Pages 2005
Roles of base excision repair enzymes Nth1p and Apn2p from Schizosaccharomyces pombe in processing alkylation and oxidative DNA damage Fulltext Access 11 Pages 2005
Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen Fulltext Access 11 Pages 2005
The p-benzoquinone DNA adducts derived from benzene are highly mutagenic Fulltext Access 11 Pages 2005
Structural insight into the DNA polymerase β deoxyribose phosphate lyase mechanism Fulltext Access 11 Pages 2005
Cloning and biochemical characterization of APIT, a new l-amino acid oxidase from Aplysia punctata Fulltext Access 11 Pages 2005
The Saccharomyces cerevisiae PDS1 and RAD9 checkpoint genes control different DNA double-strand break repair pathways Fulltext Access 11 Pages 2005
Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts Fulltext Access 11 Pages 2005
Differentiating human keratinocytes are deficient in p53 but retain global nucleotide excision repair following ultraviolet radiation Fulltext Access 11 Pages 2005
A non-radioactive, PFGE-based assay for low levels of DNA double-strand breaks in mammalian cells Fulltext Access 11 Pages 2005
Binding of MutS mismatch repair protein to DNA containing UV photoproducts, “mismatched” opposite Watson-Crick and novel nucleotides, in different DNA sequence contexts Fulltext Access 11 Pages 2005
The modulation effects of d-amphetamine and procaine on the spontaneously generated action potentials in the central neuron of snail, Achatina fulica Ferussac Fulltext Access 11 Pages 2005
Metabolic changes in Japanese medaka (Oryzias latipes) during embryogenesis and hypoxia as determined by in vivo 31P NMR Fulltext Access 11 Pages 2005
Functional characterization of medaka CYP3A38 and CYP3A40: Kinetics and catalysis by expression in a recombinant baculovirus system Fulltext Access 11 Pages 2005
Molecular characterization of the aryl hydrocarbon receptors (AHR1 and AHR2) from red seabream (Pagrus major) Fulltext Access 11 Pages 2005
Gliotoxin-induced cytotoxicity in three salmonid cell lines: Cell death by apoptosis and necrosis Fulltext Access 11 Pages 2005
Polyhydroxylated amide analogs of yessotoxin from Protoceratium reticulatum Fulltext Access 11 Pages 2005
Use of Comet assay to assess DNA damage in patients infected by Helicobacter pylori Fulltext Access 11 Pages 2005
Impact of low doses of tritium on the marine mussel, Mytilus edulis: Genotoxic effects and tissue-specific bioconcentration Fulltext Access 11 Pages 2005
Effects of environmental benzene: Micronucleus frequencies and haematological values in traffic police working in an urban area Fulltext Access 11 Pages 2005
Genotoxicity test system based on p53R2 gene expression in human cells: Examination with 80 chemicals Fulltext Access 11 Pages 2005
A novel short-chain peptide BmKX from the chinese scorpion Buthus martensi karsch, sequencing, gene cloning and structure determination Fulltext Access 11 Pages 2005
The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function Fulltext Access 11 Pages 2005
Toxicity of culturable cyanobacteria strains isolated from the Portuguese coast Fulltext Access 11 Pages 2005
Cobra cardiotoxin-induced cell death in fetal rat cardiomyocytes and cortical neurons: different pathway but similar cell surface target Fulltext Access 11 Pages 2005
Renal and antibacterial effects induced by myotoxin I and II isolated from Bothrops jararacussu venom Fulltext Access 11 Pages 2005
Microarray analysis of gene expression in chondrosarcoma cells treated with bee venom Fulltext Access 11 Pages 2005
Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels Fulltext Access 11 Pages 2005
Primary structure, behavioral and electroencephalographic effects of an epileptogenic peptide from the sea anemone Bunodosoma cangicum Fulltext Access 11 Pages 2005
Purification and characterization of a novel peptide with antifungal activity from Bothrops jararaca venom Fulltext Access 11 Pages 2005
Amino acid sequence of a basic aspartate-49-phospholipase A2 from Trimeresurus flavoviridis venom and phylogenetic analysis of Crotalinae venom phospholipases A2 Fulltext Access 11 Pages 2005
Isolation and identification of (44-R,S)-44,55-dihydroxyyessotoxin from Protoceratium reticulatum, and its occurrence in extracts of shellfish from New Zealand, Norway and Canada Fulltext Access 11 Pages 2005
Role of endogenous channels in red blood cells response to their exposure to the pore forming toxin Sticholysin II Fulltext Access 11 Pages 2005
Isolation and chemical characterization of PwTx-II: A novel alkaloid toxin from the venom of the spider Parawixia bistriata (Araneidae, Araneae) Fulltext Access 11 Pages 2005
Acid and alkaline phosphatase activities and pathological changes induced in Tilapia fish (Oreochromis sp.) exposed subchronically to microcystins from toxic cyanobacterial blooms under laboratory conditions Fulltext Access 11 Pages 2005
Enzymatic characterization, antigenic cross-reactivity and neutralization of dermonecrotic activity of five Loxosceles spider venoms of medical importance in the Americas Fulltext Access 11 Pages 2005
Tissue distributions and seasonal dynamics of the hepatotoxic microcystins-LR and -RR in two freshwater shrimps, Palaemon modestus and Macrobrachium nipponensis, from a large shallow, eutrophic lake of the subtropical China Fulltext Access 11 Pages 2005
Inhibition of N-methyl-d-aspartate receptors increases paraoxon-induced apoptosis in cultured neurons Fulltext Access 11 Pages 2005
Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation Fulltext Access 11 Pages 2005
Interactions between Streptomyces californicus and Stachybotrys chartarum can induce apoptosis and cell cycle arrest in mouse RAW264.7 macrophages Fulltext Access 11 Pages 2005
Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract Fulltext Access 11 Pages 2005
Capsaicin stimulates the non-store-operated Ca2+ entry but inhibits the store-operated Ca2+ entry in neutrophils Fulltext Access 11 Pages 2005
Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR) Fulltext Access 11 Pages 2005
In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture Fulltext Access 11 Pages 2005
Thalidomide enhances both primary and secondary host resistances to Listeria monocytogenes infection by a neutrophil-related mechanism in female B6C3F1 mice Fulltext Access 11 Pages 2005
Sex- and dose-dependency in the pharmacokinetics and pharmacodynamics of (+)-methamphetamine and its metabolite (+)-amphetamine in rats Fulltext Access 11 Pages 2005
Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE Fulltext Access 11 Pages 2005
Formation of PAH-DNA adducts after in vivo and vitro exposure of rats and lung cells to different commercial carbon blacks Fulltext Access 11 Pages 2005
4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-κB and ERK/MAPK Fulltext Access 11 Pages 2005
Functional observational battery and motor activity in rats after single administration of two NHE 1 inhibitors Fulltext Access 11 Pages 2005
A rat model of smoke inhalation injury: Influence of combustion smoke on gene expression in the brain Fulltext Access 11 Pages 2005
Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury Fulltext Access 11 Pages 2005
Comprehensive non-clinical respiratory evaluation of promising new drugs Fulltext Access 11 Pages 2005
Mercury and autoimmunity: implications for occupational and environmental health Fulltext Access 11 Pages 2005
Effect of intratracheal instillation of ultrafine carbon black on proinflammatory cytokine and chemokine release and mRNA expression in lung and lymph nodes of mice Fulltext Access 11 Pages 2005
Colcemid inhibits the rejoining of the nucleotide excision repair of UVC-induced DNA damages in Chinese hamster ovary cells Fulltext Access 11 Pages 2005
Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17β-estradiol, progesterone and Vitamin E Fulltext Access 11 Pages 2005
DNA adducts derived from administration of acrylamide and glycidamide to mice and rats Fulltext Access 11 Pages 2005
DNA damage and DNA adduct formation in rat tissues following oral administration of acrylamide Fulltext Access 11 Pages 2005
Reaction-kinetic parameters of glycidamide as determinants of mutagenic potency Fulltext Access 11 Pages 2005
Role of xenobiotic metabolizing gene polymorphisms in breast cancer susceptibility and treatment outcome Fulltext Access 11 Pages 2005
The effects of thyme volatiles on the induction of DNA damage by the heterocyclic amine IQ and mitomycin C Fulltext Access 11 Pages 2005
DNA damage measured by the single-cell gel electrophoresis (Comet) assay in mammals fed with mussels contaminated by the 'Erika' oil-spill Fulltext Access 11 Pages 2005
The Arg280His polymorphism in X-ray repair cross-complementing gene 1 impairs DNA repair ability Fulltext Access 11 Pages 2005
Nitrogen mustard- and half-mustard-induced damage in Escherichia coli requires different DNA repair pathways Fulltext Access 11 Pages 2005
Individual responsiveness to induction of micronuclei in human lymphocytes after exposure in vitro to 1800-MHz microwave radiation Fulltext Access 11 Pages 2005
Modulating effects of humic acids on genotoxicity induced by water disinfectants in Cyprinus carpio Fulltext Access 11 Pages 2005
Induction of Cyp1a1 and Cyp1b1 and formation of DNA adducts in C57BL/6, Balb/c, and F1 mice following in utero exposure to 3-methylcholanthrene Fulltext Access 11 Pages 2005
Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage Fulltext Access 11 Pages 2005
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis Fulltext Access 11 Pages 2005
Mutation of the cohesin related gene PDS5 causes cell death with predominant apoptotic features in Saccharomyces cerevisiae during early meiosis Fulltext Access 11 Pages 2005
HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy Fulltext Access 11 Pages 2005
Homologous recombination in plants is temperature and day-length dependent Fulltext Access 11 Pages 2005
Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics Fulltext Access 11 Pages 2005
Hepatic mitochondrial glutathione: transport and role in disease and toxicity Fulltext Access 11 Pages 2005
Acrylonitrile potentiates hearing loss and cochlear damage induced by moderate noise exposure in rats Fulltext Access 11 Pages 2005
Accumulation of methylmercury or polychlorinated biphenyls in in vitro models of rat neuronal tissue Fulltext Access 11 Pages 2005