A Dynamically Localized Protease Complex and a Polar Specificity Factor Control a Cell Cycle Master Regulator Fulltext Access 13 Pages 2006
Bruno Acts as a Dual Repressor of oskar Translation, Promoting mRNA Oligomerization and Formation of Silencing Particles Fulltext Access 13 Pages 2006
Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells Fulltext Access 13 Pages 2006
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin Fulltext Access 13 Pages 2006
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors Fulltext Access 13 Pages 2006
Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB Signaling Fulltext Access 13 Pages 2006
A Landmark Protein Essential for Establishing and Perpetuating the Polarity of a Bacterial Cell Fulltext Access 13 Pages 2006
Ligands for Clathrin-Mediated Endocytosis Are Differentially Sorted into Distinct Populations of Early Endosomes Fulltext Access 13 Pages 2006
Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response Fulltext Access 13 Pages 2006
CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens Fulltext Access 13 Pages 2006
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin Fulltext Access 13 Pages 2006
C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span Fulltext Access 13 Pages 2006
EphB Receptors Coordinate Migration and Proliferation in the Intestinal Stem Cell Niche Fulltext Access 13 Pages 2006
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Fulltext Access 13 Pages 2006
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Fulltext Access 13 Pages 2006
Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland Fulltext Access 13 Pages 2006
Real-Time Observation of RecA Filament Dynamics with Single Monomer Resolution Fulltext Access 13 Pages 2006
Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine Fulltext Access 13 Pages 2006
Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies Fulltext Access 13 Pages 2006
Phenotypic characterization of raw milk-associated psychrotrophic bacteria Fulltext Access 13 Pages 2006
Isolation and molecular characterization of toxigenic Vibrio parahaemolyticus from the Kii Channel, Japan Fulltext Access 13 Pages 2006
SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability Fulltext Access 13 Pages 2006
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining Fulltext Access 13 Pages 2006
Innate Immunity Gone Awry: Linking Microbial Infections to Chronic Inflammation and Cancer Fulltext Access 13 Pages 2006
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT Fulltext Access 13 Pages 2006
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome Fulltext Access 13 Pages 2006
Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly Fulltext Access 13 Pages 2006
Embryonic Dorsal-Ventral Signaling: Secreted Frizzled-Related Proteins as Inhibitors of Tolloid Proteinases Fulltext Access 13 Pages 2006
Identification of a Bacterial Type III Effector Family with G Protein Mimicry Functions Fulltext Access 13 Pages 2006
Virus-Induced Abl and Fyn Kinase Signals Permit Coxsackievirus Entry through Epithelial Tight Junctions Fulltext Access 13 Pages 2006
Structure of DDB1 in Complex with a Paramyxovirus V Protein: Viral Hijack of a Propeller Cluster in Ubiquitin Ligase Fulltext Access 13 Pages 2006
The Crystal Structure of Yeast Protein Disulfide Isomerase Suggests Cooperativity between Its Active Sites Fulltext Access 13 Pages 2006
Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription-Factor Binding Affinity Fulltext Access 13 Pages 2006
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover Fulltext Access 13 Pages 2006
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis Fulltext Access 13 Pages 2006
Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference Fulltext Access 13 Pages 2006
A Bir1-Sli15 Complex Connects Centromeres to Microtubules and Is Required to Sense Kinetochore Tension Fulltext Access 13 Pages 2006
TRPV1+ Sensory Neurons Control β Cell Stress and Islet Inflammation in Autoimmune Diabetes Fulltext Access 13 Pages 2006
Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis Fulltext Access 13 Pages 2006
Crystal Structure of the DsbB-DsbA Complex Reveals a Mechanism of Disulfide Bond Generation Fulltext Access 13 Pages 2006
The Highly Conserved LepA Is a Ribosomal Elongation Factor that Back-Translocates the Ribosome Fulltext Access 13 Pages 2006
Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins Fulltext Access 13 Pages 2006
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis Fulltext Access 13 Pages 2006
Crystal Structures of a Ligand-free MthK Gating Ring: Insights into the Ligand Gating Mechanism of K+ Channels Fulltext Access 13 Pages 2006
The RCK Domain of the KtrAB K+ Transporter: Multiple Conformations of an Octameric Ring Fulltext Access 13 Pages 2006
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells Fulltext Access 13 Pages 2006
Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements Fulltext Access 13 Pages 2006
A Neuronal Identity Code for the Odorant Receptor-Specific and Activity-Dependent Axon Sorting Fulltext Access 13 Pages 2006
Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor Fulltext Access 13 Pages 2006
Regulation of Body Pigmentation by the Abdominal-B Hox Protein and Its Gain and Loss in Drosophila Evolution Fulltext Access 13 Pages 2006
Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene Fulltext Access 13 Pages 2006
Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload Fulltext Access 13 Pages 2006
The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on mRNA Fulltext Access 13 Pages 2006
A C. elegans Model of Nicotine-Dependent Behavior: Regulation by TRP-Family Channels Fulltext Access 13 Pages 2006
A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration Fulltext Access 13 Pages 2006
Distinct Behavioral Responses to Ethanol Are Regulated by Alternate RhoGAP18B Isoforms Fulltext Access 13 Pages 2006
Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain Fulltext Access 13 Pages 2006
Tcf3 Governs Stem Cell Features and Represses Cell Fate Determination in Skin Fulltext Access 13 Pages 2006
SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity Fulltext Access 13 Pages 2006
Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation Fulltext Access 13 Pages 2006
Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations Fulltext Access 13 Pages 2006
Pot1 Deficiency Initiates DNA Damage Checkpoint Activation and Aberrant Homologous Recombination at Telomeres Fulltext Access 14 Pages 2006
Literature Highlights: Recent research in infectious disease drup resistance Fulltext Access 14 Pages 2006
Sustained upregulation of glial fibrillary acidic protein in Müller cells in pigeon retina following disruption of the parasympathetic control of choroidal blood flow Fulltext Access 14 Pages 2006
Effects of acute delivery of endothelin-1 on retinal ganglion cell loss in the rat Fulltext Access 14 Pages 2006
Nok plays an essential role in maintaining the integrity of the outer nuclear layer in the zebrafish retina Fulltext Access 14 Pages 2006
Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys Fulltext Access 14 Pages 2006
Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells Fulltext Access 14 Pages 2006
Malaria in adolescence: burden of disease, consequences, and opportunities for intervention Fulltext Access 14 Pages 2006
Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use Fulltext Access 14 Pages 2006
Literature highlights - 9/6 Recent research in infectious disease drug resistance Fulltext Access 14 Pages 2006
Rac signaling in tumorigenesis and as target for anticancer drug development Fulltext Access 14 Pages 2006
The Proteasome Restricts Permissive Transcription at Tissue-Specific Gene Loci in Embryonic Stem Cells Fulltext Access 14 Pages 2006
A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging Fulltext Access 14 Pages 2006
Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa Fulltext Access 14 Pages 2006
Toxoplasma gondii Sequesters Lysosomes from Mammalian Hosts in the Vacuolar Space Fulltext Access 14 Pages 2006
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells Fulltext Access 14 Pages 2006
An ARGONAUTE4-Containing Nuclear Processing Center Colocalized with Cajal Bodies in Arabidopsis thaliana Fulltext Access 14 Pages 2006
The Arabidopsis Chromatin-Modifying Nuclear siRNA Pathway Involves a Nucleolar RNA Processing Center Fulltext Access 14 Pages 2006