A Pathway for the Transmission of Allosteric Signals in the Ribosome through a Network of RNA Tertiary Interactions Fulltext Access 12 Pages 2006
Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient Fulltext Access 12 Pages 2006
Visualization of the Annealing of Complementary Single-stranded DNA Catalyzed by the Herpes Simplex Virus Type 1 ICP8 SSB/Recombinase Fulltext Access 12 Pages 2006
Efficient Prediction of Nucleic Acid Binding Function from Low-resolution Protein Structures Fulltext Access 12 Pages 2006
Reconstitution of Calmodulin from Domains and Subdomains: Influence of Target Peptide Fulltext Access 12 Pages 2006
The Crystal Structure of the Apoenzyme of the Iron–Sulphur Cluster-free Hydrogenase Fulltext Access 12 Pages 2006
Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen Fulltext Access 12 Pages 2006
Filling Small, Empty Protein Cavities: Structural and Energetic Consequences Fulltext Access 12 Pages 2006
A Novel-type Substrate-selectivity Filter and ER-exit Determinants in the UapA Purine Transporter Fulltext Access 12 Pages 2006
Bacillus subtilis Bacteriophage SPP1 G40P Helicase Lacking the N-terminal Domain Unwinds DNA Bidirectionally Fulltext Access 12 Pages 2006
High-resolution Crystal Structure of Aldose Reductase Complexed with the Novel Sulfonyl-pyridazinone Inhibitor Exhibiting an Alternative Active Site Anchoring Group Fulltext Access 12 Pages 2006
The Crystal Structure of Polyhydroxybutyrate Depolymerase from Penicillium funiculosum Provides Insights into the Recognition and Degradation of Biopolyesters Fulltext Access 12 Pages 2006
The N-terminal Half of the Peroxisomal Cycling Receptor Pex5p is a Natively Unfolded Domain Fulltext Access 12 Pages 2006
Crystal Structure of a Novel Viral Protease with a Serine/Lysine Catalytic Dyad Mechanism Fulltext Access 12 Pages 2006
Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.) Fulltext Access 12 Pages 2006
Artemis Phosphorylated by DNA-dependent Protein Kinase Associates Preferentially with Discrete Regions of Chromatin Fulltext Access 12 Pages 2006
Nanopore–Protein Interactions Dramatically Alter Stability and Yield of the Native State in Restricted Spaces Fulltext Access 12 Pages 2006
Structure of the α-Actinin–Vinculin Head Domain Complex Determined by Cryo-electron Microscopy Fulltext Access 12 Pages 2006
Recognition of Oxidatively Modified Bases within the Biotin-binding Site of Avidin Fulltext Access 12 Pages 2006
A long-term study in Angora goats experimentally infected with Mycobacterium avium subsp. paratuberculosis: Clinical disease, faecal culture and immunological studies Fulltext Access 12 Pages 2006
Production of a d-glycero-d-manno-heptosyltransferase mutant of Mannheimia haemolytica displaying a veterinary pathogen specific conserved LPS structure; development and functionality of antibodies to this LPS structure Fulltext Access 12 Pages 2006
Greyhound meningoencephalitis: PCR-based detection methods highlight an absence of the most likely primary inducing agents Fulltext Access 12 Pages 2006
Stability of canine distemper virus (CDV) after 20 passages in Vero-DST cells expressing the receptor protein for CDV Fulltext Access 12 Pages 2006
GTP-dependent Formation of a Ribonucleoprotein Subcomplex Required for Ribosome Biogenesis Fulltext Access 12 Pages 2006
Cis and Trans-acting Effects on a Mutational Hotspot Involving a Replication Template Switch Fulltext Access 12 Pages 2006
The Structure of the Exopolyphosphatase (PPX) from Escherichia coli O157:H7 Suggests a Binding Mode for Long Polyphosphate Chains Fulltext Access 12 Pages 2006
The 1.6 Å X-ray Structure of the Unusual c-type Cytochrome, Cytochrome cL, from the Methylotrophic Bacterium Methylobacterium extorquens Fulltext Access 12 Pages 2006
Characterization of Dual Substrate Binding Sites in the Homodimeric Structure of Escherichia coli mRNA Interferase MazF Fulltext Access 12 Pages 2006
Early Effects of Topoisomerase I Inhibition on RNA Polymerase II Along Transcribed Genes in Human Cells Fulltext Access 12 Pages 2006
Model for RNA Binding and the Catalytic Site of the RNase Kid of the Bacterial parD Toxin–Antitoxin System Fulltext Access 12 Pages 2006
R-state Haemoglobin with Low Oxygen Affinity: Crystal Structures of Deoxy Human and Carbonmonoxy Horse Haemoglobin Bound to the Effector Molecule L35 Fulltext Access 12 Pages 2006
Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies Fulltext Access 12 Pages 2006
Amyloid-β Peptide Disruption of Lipid Membranes and the Effect of Metal Ions Fulltext Access 12 Pages 2006
Alanine Scanning of MS2 Coat Protein Reveals Protein–Phosphate Contacts Involved in Thermodynamic Hot Spots Fulltext Access 12 Pages 2006
Time-resolved Small-angle X-ray Scattering Investigation of the Folding Dynamics of Heme Oxygenase: Implication of the Scaling Relationship for the Submillisecond Intermediates of Protein Folding Fulltext Access 12 Pages 2006
Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1) Fulltext Access 12 Pages 2006
The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold Fulltext Access 12 Pages 2006
Role of E. coli NusA in Phage HK022 Nun-mediated Transcription Termination Fulltext Access 12 Pages 2006
Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase Fulltext Access 12 Pages 2006
Self-association of the Transmembrane Domain of an Anthrax Toxin Receptor Fulltext Access 12 Pages 2006
The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for β-Catenin Fulltext Access 12 Pages 2006
Molecular Dynamics Simulations of the Tetracycline-repressor Protein: The Mechanism of Induction Fulltext Access 12 Pages 2006
Domain Organization and Crystal Structure of the Catalytic Domain of E. coli RluF, a Pseudouridine Synthase that Acts on 23S rRNA Fulltext Access 12 Pages 2006
Calcium-dependent Tetramer Formation of S100A8 and S100A9 is Essential for Biological Activity Fulltext Access 12 Pages 2006
Structural Basis for Substrate Recognition by the Editing Domain of Isoleucyl-tRNA Synthetase Fulltext Access 12 Pages 2006
Structure and Substrate Recognition of the Escherichia coli DNA Adenine Methyltransferase Fulltext Access 12 Pages 2006
Structural Basis of the Nucleotide Driven Conformational Changes in the AAA+ Domain of Transcription Activator PspF Fulltext Access 12 Pages 2006
A Conserved Dimer and Global Conformational Changes in the Structure of apo-PknE Ser/Thr Protein Kinase from Mycobacterium tuberculosis Fulltext Access 12 Pages 2006
A Novel Mechanism of Interaction between α-Synuclein and Biological Membranes Fulltext Access 12 Pages 2006
Crystal Structure of Nicotinic Acid Mononucleotide Adenylyltransferase from Staphyloccocus aureus: Structural Basis for NaAD Interaction in Functional Dimer Fulltext Access 12 Pages 2006
Crystal Structure of 3-Chlorocatechol 1,2-dioxygenase Key Enzyme of a New Modified Ortho-pathway from the Gram-positive Rhodococcus opacus 1CP Grown on 2-chlorophenol Fulltext Access 12 Pages 2006
1.25 Å Resolution Crystal Structures of Human Haemoglobin in the Oxy, Deoxy and Carbonmonoxy Forms Fulltext Access 12 Pages 2006
Protein Refolding in Silico with Atom-based Statistical Potentials and Conformational Search Using a Simple Genetic Algorithm Fulltext Access 12 Pages 2006
Controlling Quaternary Structure Assembly: Subunit Interface Engineering and Crystal Structure of Dual Chain Avidin Fulltext Access 12 Pages 2006
Structural Basis for Molecular Recognition in an Affibody:Affibody Complex Fulltext Access 12 Pages 2006
Structural Characterization of Set1 RNA Recognition Motifs and their Role in Histone H3 Lysine 4 Methylation Fulltext Access 12 Pages 2006
Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide Fulltext Access 12 Pages 2006
Concordant Exploration of the Kinetics of RNA Folding from Global and Local Perspectives Fulltext Access 12 Pages 2006
Structure of the Escherichia coli Quorum Sensing Protein SdiA: Activation of the Folding Switch by Acyl Homoserine Lactones Fulltext Access 12 Pages 2006
Entropically Driven MHC Class I Recognition by Human Inhibitory Receptor Leukocyte Ig-like Receptor B1 (LILRB1/ILT2/CD85j) Fulltext Access 12 Pages 2006
The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor Fulltext Access 12 Pages 2006
Local Kinetic Measures of Macromolecular Structure Reveal Partitioning among Multiple Parallel Pathways from the Earliest Steps in the Folding of a Large RNA Molecule Fulltext Access 12 Pages 2006
The Type III Flagellar Export Specificity Switch is Dependent on FliK Ruler and a Molecular Clock Fulltext Access 12 Pages 2006
Viscous Drag as the Source of Active Site Perturbation during Protease Translocation: Insights into how Inhibitory Processes are Controlled by Serpin Metastability Fulltext Access 12 Pages 2006
Do Proteins with Similar Folds Have Similar Transition State Structures? A Diffuse Transition State of the 169 Residue Apoflavodoxin Fulltext Access 12 Pages 2006
The Importance of RNA Structure in RNA Editing and a Potential Proofreading Mechanism for Correct Guide RNA:pre-mRNA Binary Complex Formation Fulltext Access 12 Pages 2006
Structure of the Neuronal Protein Calexcitin Suggests a Mode of Interaction in Signalling Pathways of Learning and Memory Fulltext Access 12 Pages 2006
Multiple Solvent Crystal Structures: Probing Binding Sites, Plasticity and Hydration Fulltext Access 12 Pages 2006
Binding Properties of Pyochelin and Structurally Related Molecules to FptA of Pseudomonas aeruginosa Fulltext Access 12 Pages 2006
Mapping a Neutralizing Epitope on the SARS Coronavirus Spike Protein: Computational Prediction Based on Affinity-selected Peptides Fulltext Access 12 Pages 2006
Arcobacter, what is known and unknown about a potential foodborne zoonotic agent! Fulltext Access 13 Pages 2006
Genetic typing and prevalence of Border disease virus (BDV) in small ruminant flocks in Spain Fulltext Access 13 Pages 2006
Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers Fulltext Access 13 Pages 2006
Adherent and invasive Escherichia coli are associated with persistent bovine mastitis Fulltext Access 13 Pages 2006
Pathogenesis of a Texas feline immunodeficiency virus isolate: An emerging subtype of clade B Fulltext Access 13 Pages 2006
The tuberculosis eradication programme in Ireland: A review of scientific and policy advances since 1988 Fulltext Access 13 Pages 2006
Recent advances in our knowledge of Mycobacterium bovis: A feeling for the organism Fulltext Access 13 Pages 2006
Crystal Structure of Penicillin-binding Protein 1a (PBP1a) Reveals a Mutational Hotspot Implicated in β-Lactam Resistance in Streptococcus pneumoniae Fulltext Access 13 Pages 2006
Structural Basis of Syndecan-4 Phosphorylation as a Molecular Switch to Regulate Signaling Fulltext Access 13 Pages 2006
During the Early Phase of HIV-1 DNA Synthesis, Nucleocapsid Protein Directs Hybridization of the TAR Complementary Sequences via the Ends of their Double-stranded Stem Fulltext Access 13 Pages 2006
Individual Metal Ligands Play Distinct Functional Roles in the Zinc Sensor Staphylococcus aureus CzrA Fulltext Access 13 Pages 2006
Solvation-assisted Pressure Tuning of Insulin Fibrillation: From Novel Aggregation Pathways to Biotechnological Applications Fulltext Access 13 Pages 2006