Indirect Readout of DNA Sequence by Papillomavirus E2 Proteins Depends Upon Net Cation Uptake Fulltext Access 17 Pages 2006
Solution Structure of a Zap1 Zinc-responsive Domain Provides Insights into Metalloregulatory Transcriptional Repression in Saccharomyces cerevisiae Fulltext Access 17 Pages 2006
Characterizing a Partially Folded Intermediate of the Villin Headpiece Domain Under Non-denaturing Conditions: Contribution of His41 to the pH-dependent Stability of the N-terminal Subdomain Fulltext Access 17 Pages 2006
The MS2 Coat Protein Shell is Likely Assembled Under Tension: A Novel Role for the MS2 Bacteriophage A Protein as Revealed by Small-angle Neutron Scattering Fulltext Access 17 Pages 2006
Structural Characterization of an Equilibrium Unfolding Intermediate in Cytochrome c Fulltext Access 17 Pages 2006
Induced Fit and “Lock and Key” Recognition of 5 S RNA by Zinc Fingers of Transcription Factor IIIA Fulltext Access 17 Pages 2006
Hospital acquired urinary tract infections in urology departments: pathogens, susceptibility and use of antibiotics: Data from the PEP and PEAP-studies Fulltext Access 17 Pages 2006
Emergence of Clostridium difficile-associated disease in North America and Europe Fulltext Access 17 Pages 2006
High-resolution Structures of Escherichia coli cDsbD in Different Redox States: A Combined Crystallographic, Biochemical and Computational Study Fulltext Access 17 Pages 2006
A DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of α4β7 integrin and an effector memory phenotype Fulltext Access 17 Pages 2006
CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection Fulltext Access 17 Pages 2006
Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses Fulltext Access 17 Pages 2006
Prolonged activation of NF-κB by human cytomegalovirus promotes efficient viral replication and late gene expression Fulltext Access 17 Pages 2006
Host cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway Fulltext Access 17 Pages 2006
Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1SF2 Nef Fulltext Access 17 Pages 2006
Lentivirus envelope protein exerts differential neuropathogenic effects depending on the site of expression and target cell Fulltext Access 17 Pages 2006
A mutant fusion (F) protein of simian virus 5 induces hemagglutinin-neuraminidase-independent syncytium formation despite the internalization of the F protein Fulltext Access 17 Pages 2006
Structural disorder within the replicative complex of measles virus: Functional implications Fulltext Access 17 Pages 2006
Alternative peptide-fusion proteins generated by out-of-frame mutations, just upstream ORFs or elongations in mutants of Human Hepatitis B Viruses Fulltext Access 17 Pages 2006
Topological Information Embodied in Local Juxtaposition Geometry Provides a Statistical Mechanical Basis for Unknotting by Type-2 DNA Topoisomerases Fulltext Access 18 Pages 2006
Single Particle Reconstructions of the Transferrin–Transferrin Receptor Complex Obtained with Different Specimen Preparation Techniques Fulltext Access 18 Pages 2006
Thermodynamic Characterization of Binding Oxytricha nova Single Strand Telomere DNA with the Alpha Protein N-terminal Domain Fulltext Access 18 Pages 2006
Travel Depth, a New Shape Descriptor for Macromolecules: Application to Ligand Binding Fulltext Access 18 Pages 2006
Structural Mimicry of CD4 by a Cross-reactive HIV-1 Neutralizing Antibody with CDR-H2 and H3 Containing Unique Motifs Fulltext Access 18 Pages 2006
RuvA is a Sliding Collar that Protects Holliday Junctions from Unwinding while Promoting Branch Migration Fulltext Access 18 Pages 2006
Mechanism and Thermodynamics of Guanidinium Chloride-induced Denaturation of ALS-associated Mutant Cu,Zn Superoxide Dismutases Fulltext Access 18 Pages 2006
Identification of Native and Non-native Structure in Kinetic Folding Intermediates of Apomyoglobin Fulltext Access 18 Pages 2006
Preclinical testing of new vaccines for tuberculosis: A comprehensive review Fulltext Access 18 Pages 2006
Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 1 Fulltext Access 18 Pages 2006
Structure of T4 Pyrimidine Dimer Glycosylase in a Reduced Imine Covalent Complex with Abasic Site-containing DNA Fulltext Access 18 Pages 2006
A Novel Lysine-rich Domain and GTP Binding Motifs Regulate the Nucleolar Retention of Human Guanine Nucleotide Binding Protein, GNL3L Fulltext Access 18 Pages 2006
Functional characterization of HIV-1 Nef mutants in the context of viral infection Fulltext Access 18 Pages 2006
Mechanistic Studies of Mini-TAR RNA/DNA Annealing in the Absence and Presence of HIV-1 Nucleocapsid Protein Fulltext Access 18 Pages 2006
Multiple Assembly States of Lumazine Synthase: A Model Relating Catalytic Function and Molecular Assembly Fulltext Access 18 Pages 2006
Expression of Distinct Classes of Titin Isoforms in Striated and Smooth Muscles by Alternative Splicing, and Their Conserved Interaction with Filamins Fulltext Access 18 Pages 2006
Preclinical evaluation of cellular immune responses elicited by a polyvalent DNA prime/protein boost HIV-1 vaccine Fulltext Access 18 Pages 2006
Solution Structure of the Hdm2 C2H2C4 RING, a Domain Critical for Ubiquitination of p53 Fulltext Access 18 Pages 2006
Assembly of the Archaeal Box C/D sRNP Can Occur via Alternative Pathways and Requires Temperature-facilitated sRNA Remodeling Fulltext Access 18 Pages 2006
Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5′-Phosphosulfate Reductase Fulltext Access 18 Pages 2006
A Large Collection of Compact Box C/D snoRNAs and their Isoforms in Euglena gracilis: Structural, Functional and Evolutionary Insights Fulltext Access 18 Pages 2006
The Structure of a Mixed GluR2 Ligand-binding Core Dimer in Complex with (S)-Glutamate and the Antagonist (S)-NS1209 Fulltext Access 18 Pages 2006
Mapping Functional Domains of Chloride Intracellular Channel (CLIC) Proteins in Vivo Fulltext Access 18 Pages 2006
Sequential Release of Promoter Contacts during Transcription Initiation to Elongation Transition Fulltext Access 18 Pages 2006
Clustering of RNA Secondary Structures with Application to Messenger RNAs Fulltext Access 18 Pages 2006
Crystal Structure of Pullulanase: Evidence for Parallel Binding of Oligosaccharides in the Active Site Fulltext Access 18 Pages 2006
Effects of Co-operative Ligand Binding on Protein Amide NH Hydrogen Exchange Fulltext Access 18 Pages 2006
Sticky DNA: in Vivo Formation in E. coli and in Vitro Association of Long GAA•TTC Tracts to Generate Two Independent Supercoiled Domains Fulltext Access 18 Pages 2006
Mapping the Folding Free Energy Surface for Metal-free Human Cu,Zn Superoxide Dismutase Fulltext Access 19 Pages 2006
Structural and Biochemical Study of Effector Molecule Recognition by the E. coli Glyoxylate and Allantoin Utilization Regulatory Protein AllR Fulltext Access 19 Pages 2006
SRY-directed DNA Bending and Human Sex Reversal: Reassessment of a Clinical Mutation Uncovers a Global Coupling between the HMG Box and its Tail Fulltext Access 19 Pages 2006
Crystal Structure of 3-Hydroxybenzoate Hydroxylase from Comamonas testosteroni Has a Large Tunnel for Substrate and Oxygen Access to the Active Site Fulltext Access 19 Pages 2006
Heterotetrameric Sarcosine Oxidase: Structure of a Diflavin Metalloenzyme at 1.85 Å Resolution Fulltext Access 19 Pages 2006
Structure of the Sulfolobus solfataricus α-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31 Fulltext Access 19 Pages 2006
In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 Å Resolution Fulltext Access 19 Pages 2006
Kinetics of Insulin-like Growth Factor II (IGF-II) Interaction with Domain 11 of the Human IGF-II/Mannose 6-phosphate Receptor: Function of CD and AB Loop Solvent-exposed Residues Fulltext Access 19 Pages 2006
Substitution of the transmembrane domain of Vpu in simian–human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques Fulltext Access 19 Pages 2006
Binding-induced Stabilization and Assembly of the Phage P22 Tail Accessory Factor Gp4 Fulltext Access 19 Pages 2006
Characterization of Kaposi's sarcoma-associated herpesvirus (KSHV) K1 promoter activation by Rta Fulltext Access 19 Pages 2006
X-ray Interference Studies of Crossbridge Action in Muscle Contraction: Evidence from Quick Releases Fulltext Access 19 Pages 2006
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting Fulltext Access 19 Pages 2006
Structural Bases of Feed-back Control of Arginine Biosynthesis, Revealed by the Structures of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga maritima and Pseudomonas aeruginosa Fulltext Access 19 Pages 2006
Purification, Properties and Extended Solution Structure of the Complex Formed between Human Immunoglobulin A1 and Human Serum Albumin by Scattering and Ultracentrifugation Fulltext Access 19 Pages 2006
Identification of a Collapsed Intermediate with Non-native Long-range Interactions on the Folding Pathway of a Pair of Fyn SH3 Domain Mutants by NMR Relaxation Dispersion Spectroscopy Fulltext Access 19 Pages 2006
Dynamics of Allostery in Hemoglobin: Roles of the Penultimate Tyrosine H bonds Fulltext Access 19 Pages 2006
Evolutionary Dynamics of Prokaryotic Transcriptional Regulatory Networks Fulltext Access 20 Pages 2006
Probing the Mechanism of Amyloidogenesis through a Tandem Repeat of the PI3-SH3 Domain Suggests a Generic Model for Protein Aggregation and Fibril Formation Fulltext Access 20 Pages 2006
Multiple U2AF65 Binding Sites within SF3b155: Thermodynamic and Spectroscopic Characterization of Protein–Protein Interactions among pre-mRNA Splicing Factors Fulltext Access 20 Pages 2006
Structural Basis of Carbohydrate Transfer Activity by Human UDP-GalNAc: Polypeptide α-N-Acetylgalactosaminyltransferase (pp-GalNAc-T10) Fulltext Access 20 Pages 2006
Oligomerisation of the Developmental Regulator Proline Rich Homeodomain (PRH/Hex) is Mediated by a Novel Proline-rich Dimerisation Domain Fulltext Access 20 Pages 2006
Peptide ELISA for measuring antibodies to N-protein of porcine reproductive and respiratory syndrome virus Fulltext Access 20 Pages 2006
A review of vaccine research and development: The human immunodeficiency virus (HIV) Fulltext Access 20 Pages 2006
A Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome Fulltext Access 20 Pages 2006
Gene Expression Profiling of Ovarian Tissues for Determination of Molecular Pathways Reflective of Tumorigenesis Fulltext Access 20 Pages 2006
Mapping the Energetics of Water–Protein and Water–Ligand Interactions with the “Natural” HINT Forcefield: Predictive Tools for Characterizing the Roles of Water in Biomolecules Fulltext Access 21 Pages 2006
Free Energy Landscapes of RNA/RNA Complexes: With Applications to snRNA Complexes in Spliceosomes Fulltext Access 21 Pages 2006
Mis-translation of a Computationally Designed Protein Yields an Exceptionally Stable Homodimer: Implications for Protein Engineering and Evolution Fulltext Access 21 Pages 2006
SRY and Human Sex Determination: The Basic Tail of the HMG Box Functions as a Kinetic Clamp to Augment DNA Bending Fulltext Access 21 Pages 2006
Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis Fulltext Access 21 Pages 2006
DNA Polymerase X From African Swine Fever Virus: Quantitative Analysis of the Enzyme–ssDNA Interactions and the Functional Structure of the Complex Fulltext Access 21 Pages 2006
Modularity of the Transcriptional Response of Protein Complexes in Yeast Fulltext Access 22 Pages 2006
Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit Fulltext Access 22 Pages 2006
Recomendaciones de GEAM/SPNS sobre el tratamiento de las alteraciones metabólicas y morfológicas en el paciente con infección por VIH Fulltext Access 22 Pages 2006
Mechanism of Chromosome Compaction and Looping by the Escherichia coli Nucleoid Protein Fis Fulltext Access 22 Pages 2006