Novel neuroprotective compound SCH-20148 rescues thymocytes and SH-SY5Y cells from thapsigargin-induced mitochondrial membrane potential reduction and cell death Fulltext Access 9 Pages 2007
Cloning and expression of canine glucagon receptor and its use to evaluate glucagon receptor antagonists in vitro and in vivo Fulltext Access 9 Pages 2007
Inhibitory effect of obovatol on nitric oxide production and activation of NF-κB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells Fulltext Access 9 Pages 2007
Peroxisome proliferator-activated receptor α-independent effects of peroxisome proliferators on cysteinyl leukotriene production in mast cells Fulltext Access 9 Pages 2007
Involvement of TRPV1-dependent and -independent components in the regulation of vagally induced contractions in the mouse esophagus Fulltext Access 9 Pages 2007
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain Fulltext Access 9 Pages 2007
Role of TGF-β1 in vascular smooth muscle cell apoptosis induced by Angiotensin II Fulltext Access 9 Pages 2007
Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants Fulltext Access 9 Pages 2007
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate Fulltext Access 9 Pages 2007
Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation Fulltext Access 9 Pages 2007
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts Fulltext Access 9 Pages 2007
Vasopressin promotes cardiomyocyte hypertrophy via the vasopressin V1A receptor in neonatal mice Fulltext Access 9 Pages 2007
Serotonin in microdialysate from the mediobasal hypothalamus increases after progesterone administration to estrogen primed macaques Fulltext Access 9 Pages 2007
Potentiation of adrenaline vasoconstrictor response by sub-threshold concentrations of U-46619 in human umbilical vein: Involvement of smooth muscle prostanoid TPα receptor isoform Fulltext Access 9 Pages 2007
Post-training intrahippocampal infusion of nicotine–bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats Fulltext Access 9 Pages 2007
Omapatrilat enhances adrenomedullin's reduction of cardiomyocyte cell death Fulltext Access 9 Pages 2007
Functional activation by central monoamines of human dopamine D4 receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes Fulltext Access 9 Pages 2007
The role of gender and sex hormones in ischemic–reperfusion injury in isolated rat hearts Fulltext Access 9 Pages 2007
Mechanisms of the antispasmodic activity of 3,5-di-t-butyl catechol (DTCAT) on rat vascular smooth muscles Fulltext Access 9 Pages 2007
Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats Fulltext Access 9 Pages 2007
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood–brain barrier damage Fulltext Access 9 Pages 2007
S18986: A positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures Fulltext Access 9 Pages 2007
Role of reverse mode Na+/Ca2+ exchanger in the cardioprotection of metabolic inhibition preconditioning in rat ventricular myocytes Fulltext Access 9 Pages 2007
Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: Inhibition of cytokine production-dependent mechanism Fulltext Access 9 Pages 2007
Antidepressant-induced undesirable weight gain: Prevention with rimonabant without interference with behavioral effectiveness Fulltext Access 9 Pages 2007
The amiodarone derivative 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015) opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle Fulltext Access 9 Pages 2007
Ethanol-induced dopamine elevation in the rat — Modulatory effects by subchronic treatment with nicotinic drugs Fulltext Access 9 Pages 2007
Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains Fulltext Access 9 Pages 2007
The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells Fulltext Access 9 Pages 2007
CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon Fulltext Access 9 Pages 2007
Mechanism underlying H2O2-induced inhibition of acetylcholine-induced contraction in rabbit tracheal smooth muscle Fulltext Access 9 Pages 2007
Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension Fulltext Access 9 Pages 2007
Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity Fulltext Access 9 Pages 2007
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2 Fulltext Access 9 Pages 2007
Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons Fulltext Access 9 Pages 2007
In vitro electrophysiological mechanisms for antiarrhythmic efficacy of resveratrol, a red wine antioxidant Fulltext Access 9 Pages 2007
YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models Fulltext Access 9 Pages 2007
Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism Fulltext Access 9 Pages 2007
Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats Fulltext Access 9 Pages 2007
Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis Fulltext Access 9 Pages 2007
Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver Fulltext Access 9 Pages 2007
Anti-inflammatory activities of ent-16αH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-κB inactivation Fulltext Access 9 Pages 2007
Oral treatment with probucol in a pharmacological dose has no beneficial effects on mortality in chronic ischemic heart failure after large myocardial infarction in rats Fulltext Access 9 Pages 2007
Behavioral effects of the R-(+)- and S-(−)-enantiomers of the dopamine D1-like partial receptor agonist SKF 83959 in monkeys Fulltext Access 9 Pages 2007
Cordycepin (3′-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner Fulltext Access 9 Pages 2007
Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats Fulltext Access 9 Pages 2007
Cilostazol, a phosphodiesterase 3 inhibitor, protects mice against acute and late ischemic brain injuries Fulltext Access 9 Pages 2007
Inhibition of the myeloperoxidase chlorinating activity by non-steroidal anti-inflammatory drugs: Flufenamic acid and its 5-chloro-derivative directly interact with a recombinant human myeloperoxidase to inhibit the synthesis of hypochlorous acid Fulltext Access 9 Pages 2007
Resveratrol enhances insulin secretion by blocking KATP and KV channels of beta cells Fulltext Access 9 Pages 2007
Phospholipase D-dependent and -independent p38MAPK activation pathways are required for superoxide production and chemotactic induction, respectively, in rat neutrophils stimulated by fMLP Fulltext Access 9 Pages 2007
Combination of VEGF165/Angiopoietin-1 gene and endothelial progenitor cells for therapeutic neovascularization Fulltext Access 9 Pages 2007
Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis Fulltext Access 9 Pages 2007
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor Fulltext Access 9 Pages 2007
Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy Fulltext Access 9 Pages 2007
Serotonin 5-HT2C receptor homodimerization is not regulated by agonist or inverse agonist treatment Fulltext Access 9 Pages 2007
Effect of conjugated linoleic acid on bone formation and rheumatoid arthritis Fulltext Access 9 Pages 2007
Importance of intracellular Angiotensin II in vascular smooth muscle cell apoptosis: Inhibition by the Angiotensin AT1 receptor antagonist irbesartan Fulltext Access 9 Pages 2007
Emodin, an anthraquinone derivative from Rheum officinale Baill, enhances cutaneous wound healing in rats Fulltext Access 9 Pages 2007
Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea Fulltext Access 9 Pages 2007
Effect of protocatechualdehyde on receptor for advanced glycation end products and TGF-β1 expression in human lens epithelial cells cultured under diabetic conditions and on lens opacity in streptozotocin-diabetic rats Fulltext Access 9 Pages 2007
Effects of antidiabetic drugs on dipeptidyl peptidase IV activity: Nateglinide is an inhibitor of DPP IV and augments the antidiabetic activity of glucagon-like peptide-1 Fulltext Access 9 Pages 2007
The serotonin reuptake inhibitor citalopram does not affect colonic sensitivity or compliance in rats Fulltext Access 9 Pages 2007
Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins Fulltext Access 9 Pages 2007
βIV-spectrin forms a diffusion barrier against L1CAM at the axon initial segment Fulltext Access 9 Pages 2007
Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella Fulltext Access 9 Pages 2007
Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice Fulltext Access 9 Pages 2007
Ca2+, CREB and krüppel: A novel KLF7-binding element conserved in mouse and human TRKB promoters is required for CREB-dependent transcription Fulltext Access 9 Pages 2007
GATAe-dependent and -independent expressions of genes in the differentiated endodermal midgut of Drosophila Fulltext Access 9 Pages 2007
Transgenic labeling of taste receptor cells in model fish under the control of the 5′-upstream region of medaka phospholipase C-beta 2 gene Fulltext Access 9 Pages 2007
Dynamic expression pattern of Nodal-related genes during left-right development in medaka Fulltext Access 9 Pages 2007
Expression of the basic helix–loop–factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells Fulltext Access 9 Pages 2007
Mitochondria, ciglitazone and liver: A neglected interaction in biochemical pharmacology Fulltext Access 9 Pages 2007
Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species Fulltext Access 9 Pages 2007
Transforming growth factor-β1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-κB pathways in human lung epithelial cells Fulltext Access 9 Pages 2007
Probiotic Lactobacillus rhamnosus GG enhances gastric ulcer healing in rats Fulltext Access 9 Pages 2007
Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats Fulltext Access 9 Pages 2007
Regulator of G protein signaling proteins differentially modulate signaling of μ and δ opioid receptors Fulltext Access 9 Pages 2007
Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters Fulltext Access 9 Pages 2007
Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro Fulltext Access 9 Pages 2007
The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain Fulltext Access 9 Pages 2007
Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine–vasopressin in rats Fulltext Access 9 Pages 2007
Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease Fulltext Access 9 Pages 2007
The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Δ9-tetrahydrocannabinol in cultured cortical neurons Fulltext Access 9 Pages 2007
Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line Fulltext Access 9 Pages 2007
Allosteric effects of R- and S-citalopram on the human 5-HT transporter: Evidence for distinct high- and low-affinity binding sites Fulltext Access 9 Pages 2007
Influence of cisplatin-induced renal failure on the α1-adrenoceptor subtype causing vasoconstriction in the kidney of the rat Fulltext Access 9 Pages 2007
Hyperbaric oxygen improves survival in heatstroke rats by reducing multiorgan dysfunction and brain oxidative stress Fulltext Access 9 Pages 2007
Protective effect of Umbelliferone on membranous fatty acid composition in streptozotocin-induced diabetic rats Fulltext Access 9 Pages 2007
Vitamin B12b increases the cytotoxicity of short-time exposure to ascorbic acid, inducing oxidative burst and iron-dependent DNA damage Fulltext Access 9 Pages 2007
Intracellular calcium stores in β-escin skinned rat and guinea-pig bladders Fulltext Access 9 Pages 2007
Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: Acute and subchronic studies in rats Fulltext Access 9 Pages 2007
Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes Fulltext Access 9 Pages 2007
Is digitalis compound-induced cardiotoxicity, mediated through guinea-pig cardiomyocytes apoptosis? Fulltext Access 9 Pages 2007
Inhibition of the α9α10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-d-aspartate receptors Fulltext Access 9 Pages 2007