Altered striatal rhythmic activity in cylindromatosis knock-out mice due to enhanced GABAergic inhibition Fulltext Access 8 Pages 2016
Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1 Fulltext Access 8 Pages 2016
P-glycoprotein differentially affects escitalopram, levomilnacipran, vilazodone and vortioxetine transport at the mouse blood-brain barrier in vivo Fulltext Access 8 Pages 2016
Role of interleukin-10 (IL-10) in regulation of GABAergic transmission and acute response to ethanol Fulltext Access 8 Pages 2016
Impairment of contextual fear extinction by chronic nicotine and withdrawal from chronic nicotine is associated with hippocampal nAChR upregulation Fulltext Access 8 Pages 2016
Alcohol drinking increases the dopamine-stimulating effects of ethanol and reduces D2 auto-receptor and group II metabotropic glutamate receptor function within the posterior ventral tegmental area of alcohol preferring (P) rats Fulltext Access 8 Pages 2016
The roles of extracellular related-kinases 1 and 2 signaling in CNS myelination Fulltext Access 8 Pages 2016
Carotid baroreceptor stimulation blood pressure response mapped in patients undergoing carotid endarterectomy (C-Map study) Fulltext Access 8 Pages 2016
Vasotocin increases dominance in the weakly electric fish Brachyhypopomus gauderio Fulltext Access 8 Pages 2016
Karyotype description of the African weakly electric fish Campylomormyrus compressirostris in the context of chromosome evolution in Osteoglossiformes Fulltext Access 8 Pages 2016
Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital Fulltext Access 8 Pages 2016
Neuroprotective effects of metformin against Aβ-mediated inhibition of long-term potentiation in rats fed a high-fat diet Fulltext Access 8 Pages 2016
Resveratrol provides neuroprotection by inhibiting phosphodiesterases and regulating the cAMP/AMPK/SIRT1 pathway after stroke in rats Fulltext Access 8 Pages 2016
MicroRNA-9 controls apoptosis of neurons by targeting monocyte chemotactic protein-induced protein 1 expression in rat acute spinal cord injury model Fulltext Access 8 Pages 2016
Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats Fulltext Access 8 Pages 2016
Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence Fulltext Access 8 Pages 2016
Transplantation of human retinal pigment epithelial cells in the nucleus accumbens of cocaine self-administering rats provides protection from seeking Fulltext Access 8 Pages 2016
Morphine-induced antinociception and reward in “humanized” mice expressing the mu opioid receptor A118G polymorphism Fulltext Access 8 Pages 2016
Evidence that activation of nuclear peroxisome proliferator-activated receptor alpha (PPARα) modulates sleep homeostasis in rats Fulltext Access 8 Pages 2016
Classifying amygdala kindling stages using quantitative assessments of extracellular recording of EEG in rats Fulltext Access 8 Pages 2016
Research reportRauwolfia vomitoria inhibits olfaction and modifies olfactory bulb cells Fulltext Access 8 Pages 2016
Research reportGABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia Fulltext Access 8 Pages 2016
Research reportEffects of naringin on learning and memory dysfunction induced by gp120 in rats Fulltext Access 8 Pages 2016
Research reportIntracerebroventricular administration of okadaic acid induces hippocampal glucose uptake dysfunction and tau phosphorylation Fulltext Access 8 Pages 2016
Research reportFingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia Fulltext Access 8 Pages 2016
Research reportERK-dependent brain-derived neurotrophic factor regulation by hesperidin in mice exposed to chronic mild stress Fulltext Access 8 Pages 2016
BDNF acting in the hypothalamus induces acute pressor responses under permissive control of angiotensin II Fulltext Access 8 Pages 2016
Mineralocorticoid receptor antagonists - pharmacodynamics and pharmacokinetic differences Fulltext Access 8 Pages 2016
Satiation and re-intake after partial withdrawal of gastric food contents: A dissociation effect in external lateral parabrachial lesioned rats Fulltext Access 8 Pages 2016
Integrating structural and mutagenesis data to elucidate GPCR ligand binding Fulltext Access 8 Pages 2016
Guiding lead optimization with GPCR structure modeling and molecular dynamics Fulltext Access 8 Pages 2016
ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons Fulltext Access 8 Pages 2016
Interferon-β1a modulates glutamate neurotransmission in the CNS through CaMKII and GluN2A-containing NMDA receptors Fulltext Access 8 Pages 2016
Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus Fulltext Access 8 Pages 2016
MicroRNA let-7d is a target of cannabinoid CB1 receptor and controls cannabinoid signaling Fulltext Access 8 Pages 2016
Tozasertib attenuates neuronal apoptosis via DLK/JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats Fulltext Access 8 Pages 2016
Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area Fulltext Access 8 Pages 2016
The CRF1 and the CRF2 receptor mediate recognition memory deficits and vulnerability induced by opiate withdrawal Fulltext Access 8 Pages 2016
Varenicline impairs extinction and enhances reinstatement across repeated cycles of nicotine self-administration in rats Fulltext Access 8 Pages 2016
Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug Fulltext Access 8 Pages 2016
Evaluating antithrombotic activity of HY023016 on rat hypercoagulable model Fulltext Access 8 Pages 2016
The influence of dopaminergic system in medial prefrontal cortex on ketamine-induced amnesia in passive avoidance task in mice Fulltext Access 8 Pages 2016
Role of 5-HT5A and 5-HT1B/1D receptors in the antinociception produced by ergotamine and valerenic acid in the rat formalin test Fulltext Access 8 Pages 2016
Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation Fulltext Access 8 Pages 2016
Gamma-decanolactone inhibits iNOS and TNF-alpha production by lipopolysaccharide-activated microglia in N9 cells Fulltext Access 8 Pages 2016
Protective mechanisms of wogonoside against Lipopolysaccharide/D-galactosamine-induced acute liver injury in mice Fulltext Access 8 Pages 2016
Effects of Buscopan on human gastrointestinal smooth muscle activity in an ex vivo model: Are there any differences for various sections? Fulltext Access 8 Pages 2016
Effects of topiroxostat and febuxostat on urinary albumin excretion and plasma xanthine oxidoreductase activity in db/db mice Fulltext Access 8 Pages 2016
Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function Fulltext Access 8 Pages 2016
Role of JAK-STAT pathway in reducing cardiomyocytes hypoxia/reoxygenation injury induced by S1P postconditioning Fulltext Access 8 Pages 2016
Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum Fulltext Access 8 Pages 2016
2,2′-Fluorine mono-carbonyl curcumin induce reactive oxygen species-Mediated apoptosis in Human lung cancer NCI-H460 cells Fulltext Access 8 Pages 2016
N-3 polyunsaturated fatty acids modulate B cell activity in pre-clinical models: Implications for the immune response to infections Fulltext Access 8 Pages 2016
Activation of islet 5-HT4 receptor regulates glycemic control through promoting insulin secretion Fulltext Access 8 Pages 2016
The paraoxonase 1 (PON1), platelet-activating factor acetylohydrolase (PAF-AH) and dimethylarginine dimethylaminohydrolase (DDAH) activity in the metformin treated normal and diabetic rats Fulltext Access 8 Pages 2016
The vitamin D receptor agonist, calcipotriol, modulates fibrogenic pathways mitigating liver fibrosis in-vivo: An experimental study Fulltext Access 8 Pages 2016
Effects of K+ channel openers on spontaneous action potentials in detrusor smooth muscle of the guinea-pig urinary bladder Fulltext Access 8 Pages 2016
Ranolazine triggers pharmacological preconditioning and postconditioning in anesthetized rabbits through activation of RISK pathway Fulltext Access 8 Pages 2016
Local-anesthetic like inhibition of the cardiac sodium channel Nav1.5 α-subunit by 5-HT3 receptor antagonists Fulltext Access 8 Pages 2016
Discovery of a new structural class of competitive hDHODH inhibitors with in vitro and in vivo anti-inflammatory, immunosuppressive effects Fulltext Access 8 Pages 2016
Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats Fulltext Access 8 Pages 2016
Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways Fulltext Access 8 Pages 2016
Maternal care affects EEG properties of spike-wave seizures (including pre- and post ictal periods) in adult WAG/Rij rats with genetic predisposition to absence epilepsy Fulltext Access 8 Pages 2016
Morphological analysis of regenerated bulbar fibers in relation to neonatal olfaction Fulltext Access 8 Pages 2016
Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice Fulltext Access 8 Pages 2016
Protective role of autophagy in methionine–choline deficient diet-induced advanced nonalcoholic steatohepatitis in mice Fulltext Access 8 Pages 2016
The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells Fulltext Access 8 Pages 2016
Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway Fulltext Access 8 Pages 2016
Further evidence for the role of histamine H3, but not H1, H2 or H4, receptors in immepip-induced inhibition of the rat cardioaccelerator sympathetic outflow Fulltext Access 8 Pages 2016
IκB kinase β inhibitor, IMD-0354, prevents allergic asthma in a mouse model through inhibition of CD4+ effector T cell responses in the lung-draining mediastinal lymph nodes Fulltext Access 8 Pages 2016
Effects of a prostagrandin EP4-receptor agonist ONO-AE1-329 on the left ventricular pressure-volume relationship in the halothane-anesthetized dogs Fulltext Access 8 Pages 2016
Increase of human prostate cancer cell (DU145) apoptosis by telmisartan through PPAR-delta pathway Fulltext Access 8 Pages 2016
Neuroprotective effect of berberine is mediated by MAPK signaling pathway in experimental diabetic neuropathy in rats Fulltext Access 8 Pages 2016
Restoration of sirt1 function by pterostilbene attenuates hypoxia-reoxygenation injury in cardiomyocytes Fulltext Access 8 Pages 2016
Apelin-36 is protective against N-methyl-D-aspartic-acid-induced retinal ganglion cell death in the mice Fulltext Access 8 Pages 2016
Celecoxib enhanced the cytotoxic effect of cisplatin in chemo-resistant gastric cancer xenograft mouse models through a cyclooxygenase-2-dependent manner Fulltext Access 8 Pages 2016
Differential regulation of the β-adrenoceptor density and cyclic AMP level with age and sex in turkey cardiac chambers Fulltext Access 8 Pages 2016
Activation of β1-adrenoceptor triggers oxidative stress mediated myocardial membrane destabilization in isoproterenol induced myocardial infarcted rats: 7-hydroxycoumarin and its counter action Fulltext Access 8 Pages 2016
Anti-hyperlipidemic and anti-peroxidative role of pterostilbene via Nrf2 signaling in experimental diabetes Fulltext Access 8 Pages 2016
Paclitaxel inhibits cell proliferation and collagen lattice contraction via TGF-β signaling pathway in human tenon's fibroblasts in vitro Fulltext Access 8 Pages 2016
Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling Fulltext Access 8 Pages 2016
Treatment effect of l-Norvaline on the sexual performance of male rats with streptozotocin induced diabetes Fulltext Access 8 Pages 2016
Inhibition of MDM2 expression by rosmarinic acid in TSLP-stimulated mast cell Fulltext Access 8 Pages 2016
Ginsenoside metabolite compound K exerts joint-protective effect by interfering with synoviocyte function mediated by TNF-α and Tumor necrosis factor receptor type 2 Fulltext Access 8 Pages 2016
Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception Fulltext Access 8 Pages 2016
Insulin-like growth factor 1 specifically up-regulates expression of modifier subunit of glutamate-cysteine ligase and enhances glutathione synthesis in SH-SY5Y cells Fulltext Access 8 Pages 2016