Liraglutide restores angiogenesis in palmitate-impaired human endothelial cells through PI3K/Akt-Foxo1-GTPCH1 pathway Fulltext Access 7 Pages 2016
Age-specific localization of NMDA receptors on oligodendrocytes dictates axon function recovery after ischemia Fulltext Access 7 Pages 2016
Label-free visualization of cholesteatoma in the mastoid and tympanic membrane using CARS microscopy Fulltext Access 7 Pages 2016
Human otoacariasis: Demographic and clinical outcomes in patients with ear-canal ticks and a review of literature Fulltext Access 7 Pages 2016
LncRNA NONRATT021972 siRNA rescued decreased heart rate variability in diabetic rats in superior cervical ganglia Fulltext Access 7 Pages 2016
The effect of serum BDNF levels on central serotonin transporter availability in obese versus non-obese adults: A [11C]DASB positron emission tomography study Fulltext Access 7 Pages 2016
Orexin-1 receptor blockade suppresses compulsive-like alcohol drinking in mice Fulltext Access 7 Pages 2016
Selective activation of α7 nicotinic acetylcholine receptors augments hippocampal oscillations Fulltext Access 7 Pages 2016
Phage-display screening identifies LMP1-binding peptides targeting the C-terminus region of the EBV oncoprotein Fulltext Access 7 Pages 2016
Lunasin is a redox sensitive intrinsically disordered peptide with two transiently populated α-helical regions Fulltext Access 7 Pages 2016
Vilazodone does not inhibit sexual behavior in male rats in contrast to paroxetine: A role for 5-HT1A receptors? Fulltext Access 7 Pages 2016
ReviewAssociation between nesfatin-1 levels and metabolic improvements in severely obese patients who underwent biliopancreatic derivation with duodenal switch Fulltext Access 7 Pages 2016
Music exposure improves spatial cognition by enhancing the BDNF level of dorsal hippocampal subregions in the developing rats Fulltext Access 7 Pages 2016
Decreased IDE and IGF2 expression but increased Aβ40 in the cerebral cortex of mouse pups by early life lead exposure Fulltext Access 7 Pages 2016
Curcumin pretreatment attenuates inflammation and mitochondrial dysfunction in experimental stroke: The possible role of Sirt1 signaling Fulltext Access 7 Pages 2016
Remission of depression following electroconvulsive therapy (ECT) is associated with higher levels of brain-derived neurotrophic factor (BDNF) Fulltext Access 7 Pages 2016
Preconditioning of H2S inhalation protects against cerebral ischemia/reperfusion injury by induction of HSP70 through PI3K/Akt/Nrf2 pathway Fulltext Access 7 Pages 2016
Suppressor of cytokine signaling 2 (SOCS2) contributes to encephalitis in a model of Herpes infection in mice Fulltext Access 7 Pages 2016
Modulation of nociception by medial pre-optic area orexin a receptors and its relation with morphine in male rats Fulltext Access 7 Pages 2016
Mangiferin alleviates lipopolysaccharide and D-galactosamine-induced acute liver injury by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation Fulltext Access 7 Pages 2016
Research reportThe serotonin reuptake inhibitor citalopram suppresses activity in the neonatal rat barrel cortex in vivo Fulltext Access 7 Pages 2016
Creating a 'social zeitgeber' to synchronize family emotional rhythms: A new therapeutic approach in child and adolescent psychiatry Fulltext Access 7 Pages 2016
Insulin receptor regulates food intake through sulfakinin signaling in the red flour beetle, Tribolium castaneum Fulltext Access 7 Pages 2016
Newly identified allatostatin Bs and their receptor in the two-spotted cricket, Gryllus bimaculatus Fulltext Access 7 Pages 2016
[des-Arg1]-Proctolin: A novel NEP-like enzyme inhibitor identified in Tityus serrulatus venom Fulltext Access 7 Pages 2016
Corticosterone enhances N-methyl-d-aspartate receptor signaling to promote isolated ventral tegmental area activity in a reconstituted mesolimbic dopamine pathway Fulltext Access 7 Pages 2016
Research reportTempol prevents chronic sleep-deprivation induced memory impairment Fulltext Access 7 Pages 2016
Research reportLocal administration of resveratrol inhibits excitability of nociceptive wide-dynamic range neurons in rat trigeminal spinal nucleus caudalis Fulltext Access 7 Pages 2016
Research reportSOCS1 regulates neuropathic pain by inhibiting neuronal sensitization and glial activation in mouse spinal cord Fulltext Access 7 Pages 2016
Research reportPlatelet-activating factor receptor (PAFR) plays a crucial role in experimental global cerebral ischemia and reperfusion Fulltext Access 7 Pages 2016
The synthetic melanocortin (CKPV)2 exerts broad anti-inflammatory effects in human neutrophils Fulltext Access 7 Pages 2016
Research reportPeripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia Fulltext Access 7 Pages 2016
Research reportPI3K/AKT/mTOR-mediated autophagy in the development of autism spectrum disorder Fulltext Access 7 Pages 2016
Research reportIntra-amygdala microinjections of chlorpheniramine impair memory formation or memory retrieval in anxiety- and fear-mediated models Fulltext Access 7 Pages 2016
ReviewResearch progress in NOS1AP in neurological and psychiatric diseases Fulltext Access 7 Pages 2016
Review(WNK)ing at death: With-no-lysine (Wnk) kinases in neuropathies and neuronal survival Fulltext Access 7 Pages 2016
The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice Fulltext Access 7 Pages 2016
5-(4-hydroxy-3-dimethoxybenzylidene)-rhodanine (RD-1)-improved mitochondrial function prevents anxiety- and depressive-like states induced by chronic corticosterone injections in mice Fulltext Access 7 Pages 2016
Studies on the reproductive effects of chronic treatment with agomelatine in the rat Fulltext Access 7 Pages 2016
Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest Fulltext Access 7 Pages 2016
LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity Fulltext Access 7 Pages 2016
Is insulin-like growth factor 1 (IGF-1) system an attractive target inflammatory bowel diseases? Benefits and limitation of potential therapy Fulltext Access 7 Pages 2016
Endocannabinoid mechanism for orofacial antinociception induced by electroacupuncture in acupoint St36 in rats Fulltext Access 7 Pages 2016
N-3 long chain polyunsaturated fatty acids increase the expression of PPARγ-target genes and resistance of isolated heart and cultured cardiomyocytes to ischemic injury Fulltext Access 7 Pages 2016
Characteristics, diagnosis and therapeutic strategies for IgG4-related orbital disease Fulltext Access 7 Pages 2016
The protective effect of epicatechin on experimental ulcerative colitis in mice is mediated by increasing antioxidation and by the inhibition of NF-κB pathway Fulltext Access 7 Pages 2016
Management of side effects of mTOR inhibitors in tuberous sclerosis patients Fulltext Access 7 Pages 2016
Antinociceptive activity of intraperitoneally administered novel and potent anticonvulsive compound, CY-PROLL-SS, in animal neuropathic pain models Fulltext Access 7 Pages 2016
NO synthase inhibition attenuates EDHF-mediated relaxation induced by TRPV4 channel agonist GSK1016790A in the rat pulmonary artery: Role of TxA2 Fulltext Access 7 Pages 2016
The inhibitory effects of nifedipine on outward voltage-gated potassium currents in mouse neuroblastoma N2A cells Fulltext Access 7 Pages 2016
Embelin inhibits proliferation, induces apoptosis and alters gene expression profiles in breast cancer cells Fulltext Access 7 Pages 2016
Melatonin and neurotrophins NT-3, BDNF, NGF in patients with varying levels of depression severity Fulltext Access 7 Pages 2016
Transplant drugs affect the expression of phase II and antioxidant enzymes in human carcinoma cells HepG2 but not in primary cultures of human hepatocytes: In vitro comparative study Fulltext Access 7 Pages 2016
NH125 reduces the level of CPEB3, an RNA binding protein, to promote synaptic GluA2 expression Fulltext Access 7 Pages 2016
Baclofen differentially mediates fructose-conditioned flavor preference and quinine-conditioned flavor avoidance in rats Fulltext Access 7 Pages 2016
PPARγ activation alters fatty acid composition in adipose triglyceride, in addition to proliferation of small adipocytes, in insulin resistant high-fat fed rats Fulltext Access 7 Pages 2016
Antioxidant effect of 1,3,4-thiadiazolium mesoionic derivatives on isolated mitochondria Fulltext Access 7 Pages 2016
Antinociception of spirocyclopiperazinium salt compound LXM-10-M targeting α7 nicotinic receptor and M4 muscarinic receptor and inhibiting CaMKIIα/CREB/CGRP signaling pathway in mice Fulltext Access 7 Pages 2016
Effects of the mas-related gene (Mrg) C receptor agonist BAM6-22 on nociceptive reflex activity in naive, monoarthritic and mononeuropathic rats after intraplantar and intrathecal administration Fulltext Access 7 Pages 2016
Notoginsenoside R1 inhibits oxidized low-density lipoprotein induced inflammatory cytokines production in human endothelial EA.hy926 cells Fulltext Access 7 Pages 2016
Opiorphin causes a panicolytic-like effect in rat panic models mediated by μ-opioid receptors in the dorsal periaqueductal gray Fulltext Access 7 Pages 2016
Epicutaneous (EC) immunization with type II collagen (COLL II) induces CD4+ CD8+ T suppressor cells that protect from collagen-induced arthritis (CIA) Fulltext Access 7 Pages 2016
Olfactory bulbectomy-induced changes in phospholipids and protein profiles in the hippocampus and prefrontal cortex of rats. A preliminary study using a FTIR spectroscopy Fulltext Access 8 Pages 2016
Pulmonary, gastrointestinal and urogenital pharmacologyGlucose-independent renoprotective mechanisms of the tissue dipeptidyl peptidase-4 inhibitor, saxagliptin, in Dahl salt-sensitive hypertensive rats Fulltext Access 8 Pages 2016
Effect of trans-chalcone on atheroma plaque formation, liver fibrosis and adiponectin gene expression in cholesterol-fed NMRI mice Fulltext Access 8 Pages 2016
Narrow time window of metabolic changes associated with transition to overt heart failure in Tgaq*44 mice Fulltext Access 8 Pages 2016
Imidazoacridinone antitumor agent C-1311 as a selective mechanism-based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes Fulltext Access 8 Pages 2016
Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats Fulltext Access 8 Pages 2016
Effects of ketamine administration on the phosphorylation levels of CREB and TrKB and on oxidative damage after infusion of MEK inhibitor Fulltext Access 8 Pages 2016
Expression of RYamide in the nervous and endocrine system of Bombyx mori Fulltext Access 8 Pages 2016
Nuclear factor E2-related factor-2 (Nrf2) expression and regulation in male reproductive tract Fulltext Access 8 Pages 2016
Naturally-occurring TGR5 agonists modulating glucagon-like peptide-1 biosynthesis and secretion Fulltext Access 8 Pages 2016
Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes Fulltext Access 8 Pages 2016
Effect of D609 on the expression of GADD45β protein: Potential inhibitory role in the growth of glioblastoma cancer stem like cells Fulltext Access 8 Pages 2016
Effect of nebivolol treatment during pregnancy on the intrauterine fetal growth, mortality and pup postnatal development in the l-NAME-induced hypertensive rats Fulltext Access 8 Pages 2016
High fructose-mediated attenuation of insulin receptor signaling does not affect PDGF-induced proliferative signaling in vascular smooth muscle cells Fulltext Access 8 Pages 2016
Original Research ArticleAdd-on therapy with anagliptin in Japanese patients with type-2 diabetes mellitus treated with metformin and miglitol can maintain higher concentrations of biologically active GLP-1/total GIP and a lower concentration of leptin Fulltext Access 8 Pages 2016
Hydrogen sulfide down-regulates BACE1 and PS1 via activating PI3K/Akt pathway in the brain of APP/PS1 transgenic mouse Fulltext Access 8 Pages 2016
Protective effects of MCR-1329, a dual α1 and angII receptor antagonist, in mineralocorticoid-induced hypertension Fulltext Access 8 Pages 2016
Ginsenoside Re reduces Aβ production by activating PPARγ to inhibit BACE1 in N2a/APP695 cells Fulltext Access 8 Pages 2016
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model Fulltext Access 8 Pages 2016
Novel n-3 PUFA monoacylglycerides of pharmacological and medicinal interest: Anti-inflammatory and anti-proliferative effects Fulltext Access 8 Pages 2016
The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice Fulltext Access 8 Pages 2016
Design, synthesis, anticonvulsant, and antiarrhythmic properties of novel N-Mannich base and amide derivatives of β-tetralinohydantoin Fulltext Access 8 Pages 2016
Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice Fulltext Access 8 Pages 2016
Pharmacological induction of hemeoxygenase-1 activity attenuates intracerebroventricular streptozotocin induced neurocognitive deficit and oxidative stress in rats Fulltext Access 8 Pages 2016
Modification of 5-methoxy-N,N-dimethyltryptamine-induced hyperactivity by monoamine oxidase A inhibitor harmaline in mice and the underlying serotonergic mechanisms Fulltext Access 8 Pages 2016
RISK pathway is involved in oxytocin postconditioning in isolated rat heart Fulltext Access 8 Pages 2016
Molecular and cellular pharmacologyThe effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines Fulltext Access 8 Pages 2016
Propofol enhances facial stimulation-evoked responses in the cerebellar granule cell layer via NMDA receptor activation in mice in vivo Fulltext Access 8 Pages 2016
Cardiovascular pharmacologyWISP1 overexpression promotes proliferation and migration of human vascular smooth muscle cells via AKT signaling pathway Fulltext Access 8 Pages 2016
Cardiovascular pharmacologyThe active metabolite of prasugrel, R-138727, improves cerebral blood flow and reduces cerebral infarction and neurologic deficits in a non-human primate model of acute ischaemic stroke Fulltext Access 8 Pages 2016
GHSR-1a is a novel pro-angiogenic and anti-remodeling target in rats after myocardial infarction Fulltext Access 8 Pages 2016
Cardiovascular pharmacologyBlock of Na+/Ca2+ exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation Fulltext Access 8 Pages 2016
Pulmonary, gastrointestinal and urogenital pharmacologyPotent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats Fulltext Access 8 Pages 2016
N-pentyl-nitrofurantoin induces apoptosis in HL-60 leukemia cell line by upregulating BAX and downregulating BCL-xL gene expression Fulltext Access 8 Pages 2016