Crystallographic studies on two bioisosteric analogues, N-acetyl-β-d-glucopyranosylamine and N-trifluoroacetyl-β-d-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase Fulltext Access 9 Pages 2006
Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity Fulltext Access 9 Pages 2006
Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase Fulltext Access 9 Pages 2006
Comparative molecular field analysis and comparative molecular similarity indices analysis of boron-containing human thymidine kinase 1 substrates Fulltext Access 9 Pages 2006
Bis-imidazoles as molecular probes for peripheral sites of the zinc endopeptidase of botulinum neurotoxin serotype A Fulltext Access 9 Pages 2006
Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: Various DNA binding geometry and interesting antitumor capacity Fulltext Access 9 Pages 2006
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system Fulltext Access 9 Pages 2006
Structure–activity relationship of natural and synthetic coumarins inhibiting the multidrug transporter P-glycoprotein Fulltext Access 9 Pages 2006
Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases Fulltext Access 9 Pages 2006
Reassessing the melatonin pharmacophore—Enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue Fulltext Access 9 Pages 2006
Synthesis and biological evaluation of novel heterocyclic ionone-like derivatives as anti-inflammatory agents Fulltext Access 9 Pages 2006
New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: Analogues of HEAT as ligands for the α1-adrenergic receptor subtypes Fulltext Access 9 Pages 2006
Spin trapping of C- and O-centered radicals with methyl-, ethyl-, pentyl-, and phenyl-substituted EMPO derivatives Fulltext Access 9 Pages 2006
Crystallographic studies on N-azidoacetyl-β-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-β-d-glucopyranosylamine Fulltext Access 9 Pages 2006
Synthesis of 26,27-bisnorcastasterone analogs and analysis of conformation–activity relationship for brassinolide-like activity Fulltext Access 10 Pages 2006
DNA binding potential and cytotoxicity of newly designed pyrrolobenzodiazepine dimers linked through a piperazine side-armed-alkane spacer Fulltext Access 10 Pages 2006
Synthesis and biological evaluation of deoxy salacinols, the role of polar substituents in the side chain on the α-glucosidase inhibitory activity Fulltext Access 10 Pages 2006
Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum Fulltext Access 10 Pages 2006
2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands Fulltext Access 10 Pages 2006
A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11 Fulltext Access 10 Pages 2006
The development of 3D-QSAR study and recursive partitioning of heterocyclic quinone derivatives with antifungal activity Fulltext Access 10 Pages 2006
Synthesis of hypermodified adenosine derivatives as selective adenosine A3 receptor ligands Fulltext Access 10 Pages 2006
Synthesis of multisubstituted quinolines from Baylis–Hillman adducts obtained from substituted 2-chloronicotinaldehydes and their antimicrobial activity Fulltext Access 10 Pages 2006
Antioxidant activity of β-blockers: An effect mediated by scavenging reactive oxygen and nitrogen species? Fulltext Access 10 Pages 2006
Novel cyano- and amidino-substituted derivatives of thieno[2,3-b]- and thieno[3,2-b]thiophene-2-carboxanilides and thieno[3′,2′:4,5]thieno- and thieno[2′,3′:4,5]thieno [2,3-c]quinolones: Synthesis, photochemical synthesis, DNA binding, and antitumor evalu Fulltext Access 10 Pages 2006
Synthesis and in vitro evaluation of pseudosaccharinamine derivatives as potential elastase inhibitors Fulltext Access 10 Pages 2006
QSAR models for Daphnia toxicity of pesticides based on combinations of topological parameters of molecular structures Fulltext Access 10 Pages 2006
Synthesis of verbenachalcone congeners and their biological assessment against activation of the NGF-mediated neurite outgrowth of PC12D cells’ activity Fulltext Access 10 Pages 2006
Synthesis and structure–activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities Fulltext Access 10 Pages 2006
Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists Fulltext Access 10 Pages 2006
Graphene quantum dots enhance anticancer activity of cisplatin via increasing its cellular and nuclear uptake Fulltext Access 10 Pages 2006
Carbonic anhydrase inhibitors: Transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters Fulltext Access 10 Pages 2006
Synthesis of new bioactive venlafaxine analogs: Novel thiazolidin-4-ones as antimicrobials Fulltext Access 10 Pages 2006
Effect of cholesterol on DMPC phospholipid membranes and QSAR model construction in membrane-interaction QSAR study through molecular dynamics simulation Fulltext Access 10 Pages 2006
Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions Fulltext Access 10 Pages 2006
N-Thiolated β-lactam antibacterials: Effects of the N-organothio substituent on anti-MRSA activity Fulltext Access 10 Pages 2006
Hydroxyl-terminated peptidomimetic inhibitors of neuronal nitric oxide synthase Fulltext Access 10 Pages 2006
[(S)-γ-(Arylamino)prolyl]thiazolidine compounds as a novel series of potent and stable DPP-IV inhibitors Fulltext Access 10 Pages 2006
Comparative structure–activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors Fulltext Access 10 Pages 2006
Novel 2-substituted nitronyl nitroxides as free radical scavengers: Synthesis, biological evaluation and structure–activity relationship Fulltext Access 10 Pages 2006
Synthesis of some substituted pyrazinopyridoindoles and 3D QSAR studies along with related compounds: Piperazines, piperidines, pyrazinoisoquinolines, and diphenhydramine, and its semi-rigid analogs as antihistamines (H1) Fulltext Access 10 Pages 2006
Antitumor agents 251: Synthesis, cytotoxic evaluation, and structure–activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents Fulltext Access 10 Pages 2006
Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416 Fulltext Access 10 Pages 2006
Phosphatidylinositol mannosides: Synthesis and adjuvant properties of phosphatidylinositol di- and tetramannosides Fulltext Access 10 Pages 2006
Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET Fulltext Access 10 Pages 2006
Synthesis, characterization, and anti-bacterial efficacy of some novel cyclophane amide Fulltext Access 10 Pages 2006
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives Fulltext Access 10 Pages 2006
A platform for designing HIV integrase inhibitors. Part 2: A two-metal binding model as a potential mechanism of HIV integrase inhibitors Fulltext Access 10 Pages 2006
Design, synthesis, and evaluation of a novel series of α-substituted phenylpropanoic acid derivatives as human peroxisome proliferator-activated receptor (PPAR) α/δ dual agonists for the treatment of metabolic syndrome Fulltext Access 10 Pages 2006
Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs Fulltext Access 10 Pages 2006
Biochemical and functional characterization of an l-amino acid oxidase isolated from Bothrops pirajai snake venom Fulltext Access 10 Pages 2006
Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl carbamate analogs as σ2 receptor ligands Fulltext Access 10 Pages 2006
Synthesis of dopamine transporter selective 3-diarylmethoxymethyl-8-arylalkyl-8-azabicyclo[3.2.1]octane derivatives Fulltext Access 10 Pages 2006
Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands Fulltext Access 10 Pages 2006
Synthesis of 2,4,6-trisubstituted pyrimidine and triazine heterocycles as antileishmanial agents Fulltext Access 10 Pages 2006
Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12 Fulltext Access 10 Pages 2006
Trace element status in Saudi patients with established atherosclerosis Fulltext Access 10 Pages 2006
Biomonitoring of 37 trace elements in blood samples from inhabitants of northern Germany by ICP–MS Fulltext Access 10 Pages 2006
Total syntheses of three copper (II) tetracarboranylphenylporphyrins containing 40 or 80 boron atoms and their biological properties in EMT-6 tumor-bearing mice Fulltext Access 10 Pages 2006
Perception of the voicing distinction in speech produced during simultaneous communication Fulltext Access 10 Pages 2006
Comparing fixed- and randomized-interval spaced retrieval in anomia treatment Fulltext Access 10 Pages 2006
Emotional intelligence: The Sine Qua Non for a clinical leadership toolbox Fulltext Access 10 Pages 2006
Brainstem circuits that control mastication: Do they have anything to say during speech? Fulltext Access 10 Pages 2006
Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties Fulltext Access 10 Pages 2006
Fabrication of biofunctional nanomaterials via Escherichia coli OmpF protein air/water interface insertion/integration with copolymeric amphiphiles Fulltext Access 10 Pages 2006
Analysis of plantar pressure in diabetic type 2 subjects with and without neuropathy Fulltext Access 10 Pages 2006
Fondements mécaniques d'un modèle articulaire : biomécanique, mécanobiologie et mécanotransduction Fulltext Access 10 Pages 2006
Optimizing phenylethylphosphonamidates for the inhibition of prostate-specific membrane antigen Fulltext Access 10 Pages 2006
Synthesis and appetite suppressant activity of 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes as conformationally rigid analogues of fluoxetine Fulltext Access 10 Pages 2006
New cytotoxic furoquinones obtained from terpenyl-1,4-naphthoquinones and 1,4-anthracenediones Fulltext Access 10 Pages 2006
Synthesis of novel 5-substituted indirubins as protein kinases inhibitors Fulltext Access 10 Pages 2006
N-Terminal amino acid side-chain cleavage of chemically modified peptides in the gas phase: A mass spectrometry technique for N-terminus identification Fulltext Access 10 Pages 2006
The lethal effect of bis-type azridinylnaphthoquinone derivative on oral cancer cells (OEC-M1) associated with anti-apoptotic protein bcl-2 Fulltext Access 10 Pages 2006
Coronary extraction and characterization in multi-detector computed tomography Fulltext Access 10 Pages 2006
Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin Fulltext Access 10 Pages 2006
Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones Fulltext Access 10 Pages 2006
Fluorescein-based amino acids for solid phase synthesis of fluorogenic protease substrates Fulltext Access 10 Pages 2006
Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis Fulltext Access 10 Pages 2006
Aponeocarzinostatin-A superior drug carrier exhibiting unusually high endurance against denaturants Fulltext Access 10 Pages 2006
Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC) Fulltext Access 10 Pages 2006
Synthesis and SAR studies of a novel series of T-type calcium channel blockers Fulltext Access 10 Pages 2006
Fluorescent intercalator displacement analyses of DNA binding by the peptide-derived natural products netropsin, actinomycin, and bleomycin Fulltext Access 10 Pages 2006
Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): Molecular docking and 3D-QSAR analyses on DHDMBF analogues Fulltext Access 10 Pages 2006
Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid: Potent inhibition of histone deacetylases Fulltext Access 10 Pages 2006
Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis Fulltext Access 10 Pages 2006
High-mannose-type glycan modifications of dihydrofolate reductase using glycan–methotrexate conjugates Fulltext Access 10 Pages 2006