Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress Fulltext Access 10 Pages 2006
The role of ATP sensitive K+ channels and of nitric oxide synthase on myocardial ischemia/reperfusion-induced apoptosis Fulltext Access 10 Pages 2006
Transitional angiogenesis and vascular remodeling during coronary angiogenesis in response to myocardial infarction Fulltext Access 10 Pages 2006
Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography–electrochemical detection coupled with immunoaffinity purification: Association with cigarette smoking Fulltext Access 10 Pages 2006
Nitric oxide protects the mitochondria of anterior pituitary cells and prevents cadmium-induced cell death by reducing oxidative stress Fulltext Access 10 Pages 2006
Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith–Lemli–Opitz syndrome Fulltext Access 10 Pages 2006
Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia–reperfusion Fulltext Access 10 Pages 2006
Inhibition of sphingosine-1-phosphate- and vascular endothelial growth factor-induced endothelial cell chemotaxis by red grape skin polyphenols correlates with a decrease in early platelet-activating factor synthesis Fulltext Access 10 Pages 2006
Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression Fulltext Access 10 Pages 2006
The nitroxide Tempol modulates anthracycline resistance in breast cancer cells Fulltext Access 10 Pages 2006
Heme oxygenase-1 contributes to the cytoprotection of alpha-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells Fulltext Access 10 Pages 2006
A mouse model for human atherosclerosis: Long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice Fulltext Access 10 Pages 2006
Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines Fulltext Access 10 Pages 2006
Saccharomyces cerevisiae strain expressing a plant fatty acid desaturase produces polyunsaturated fatty acids and is susceptible to oxidative stress induced by lipid peroxidation Fulltext Access 10 Pages 2006
In vivo generation of free radicals in the skin of live mice under ultraviolet light, measured by L-band EPR spectroscopy Fulltext Access 10 Pages 2006
Ascorbic acid suppresses cell death in rat DS-sarcoma cancer cells induced by 5-aminolevulinic acid-based photodynamic therapy Fulltext Access 10 Pages 2006
Long-term exposure to oxidized low-density lipoprotein enhances tumor necrosis factor-α-stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways Fulltext Access 10 Pages 2006
A convenient approach for evaluating the toxicity profiles of in vitro neuroprotective alkylaminophenol derivatives Fulltext Access 10 Pages 2006
As(III) transcriptionally activates the gadd45a gene via the formation of H2O2 Fulltext Access 10 Pages 2006
Metalloprotein-dependent decomposition of S-nitrosothiols: Studies on the stabilization and measurement of S-nitrosothiols in tissues Fulltext Access 10 Pages 2006
A new terbium(III) chelate as an efficient singlet oxygen fluorescence probe Fulltext Access 10 Pages 2006
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides Fulltext Access 10 Pages 2006
Reduced nonprotein thiols inhibit activation and function of MMP-9: Implications for chemoprevention Fulltext Access 10 Pages 2006
A novel strategy to identify the regulatory DNA-organized cooperations among transcription factors Fulltext Access 10 Pages 2006
Evidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cells Fulltext Access 10 Pages 2006
Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia Fulltext Access 10 Pages 2006
Overexpression of E2A proteins induces epithelial–mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis Fulltext Access 10 Pages 2006
Cold acclimation of the Arabidopsis dgd1 mutant results in recovery from photosystem I-limited photosynthesis Fulltext Access 10 Pages 2006
Reconstruction and in silico analysis of the MAPK signaling pathways in the human blood fluke, Schistosoma japonicum Fulltext Access 10 Pages 2006
Divergent evolutionary lines of fungal cytochrome c peroxidases belonging to the superfamily of bacterial, fungal and plant heme peroxidases Fulltext Access 10 Pages 2006
CRSBP-1/LYVE-l-null mice exhibit identifiable morphological and functional alterations of lymphatic capillary vessels Fulltext Access 10 Pages 2006
Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria Fulltext Access 10 Pages 2006
p205, A potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation Fulltext Access 10 Pages 2006
Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells Fulltext Access 10 Pages 2006
Microtubule cytoskeleton behavior in the initial steps of host cell invasion by Besnoitia besnoiti Fulltext Access 10 Pages 2006
Proteasomal degradation of the multifunctional regulator YB-1 is mediated by an F-Box protein induced during programmed cell death Fulltext Access 10 Pages 2006
Hypobaric-hypoxia-induced pulmonary damage in rats ameliorated by antioxidant erdosteine Fulltext Access 10 Pages 2006
Immunohistochemical labelling of components of the endoneurial extracellular matrix of intact and rhizotomized dorsal and ventral spinal roots of the rat – a quantitative evaluation using image analysis Fulltext Access 10 Pages 2006
Analysis of unconventional approaches for the rapid detection of surface lectin binding ligands on human cell lines Fulltext Access 10 Pages 2006
A microscopic survey on the efficiency of well-known routine chemical fixatives on cryosections Fulltext Access 10 Pages 2006
The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: Application to a lead optimization of a human A3 adenosine receptor antagonist Fulltext Access 10 Pages 2006
Structure–activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonists Fulltext Access 10 Pages 2006
Synthesis, reactions and structure–activity relationships of 1-hydroxyspiro[2.5]cyclooct-4-en-3-ones: Illudin analogs with in vitro cytotoxic activity Fulltext Access 10 Pages 2006
QSAR analysis of antimicrobial and haemolytic effects of cyclic cationic antimicrobial peptides derived from protegrin-1 Fulltext Access 10 Pages 2006
The binding of 3′-N-piperidine-4-carboxyl-3′-deoxy-ara-uridine to ribonuclease A in the crystal Fulltext Access 10 Pages 2006
Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2′-hydroxy) benzoyl hydrazone Fulltext Access 10 Pages 2006
Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity Fulltext Access 10 Pages 2006
Synthesis and biological evaluation of carboacyclic nucleosides with (Z) and (E)-9-[4,4-bis(hydroxymethyl)]-2-butenyl side chain Fulltext Access 10 Pages 2006
Synthesis of 1-O-monoacyl or 12-O-monoacyl, 1-,12-O-diacyl-, and 11,12-dehydrated excisanin A 7,14-acetonides and their cytotoxic activity Fulltext Access 10 Pages 2006
Preserving nature? Ecology, tourism and other themes in the national parks Fulltext Access 10 Pages 2006
Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds Fulltext Access 10 Pages 2006
A comparative survey on alcohol and tobacco use in urban and rural populations in the Huaihua District of Hunan Province, China Fulltext Access 10 Pages 2006
Metabolic basis of ethanol-induced hepatic and pancreatic injury in hepatic alcohol dehydrogenase deficient deer mice Fulltext Access 10 Pages 2006
Chronic-alcohol exposure alters IGF1 signaling in H9c2 cells via changes in PKC delta Fulltext Access 10 Pages 2006
SR147778, a CB1 cannabinoid receptor antagonist, suppresses ethanol preference in chronically alcoholized Wistar rats Fulltext Access 10 Pages 2006
Activation of serotonin-3 receptors increases dopamine release within the ventral tegmental area of Wistar and alcohol-preferring (P) rats Fulltext Access 10 Pages 2006
Comparing the EQ-5D and the SF-6D Descriptive Systems to Assess Their Ceiling Effects in the US General Population Fulltext Access 10 Pages 2006
WaveRead: Automatic measurement of relative gene expression levels from microarrays using wavelet analysis Fulltext Access 10 Pages 2006
Traversing the tangle: Algorithms and applications for cophylogenetic studies Fulltext Access 10 Pages 2006
Validation by simulation of a clinical trial model using the standardized mean and variance criteria Fulltext Access 10 Pages 2006
Using ontologies linked with geometric models to reason about penetrating injuries Fulltext Access 10 Pages 2006
Integrating regression formulas and kernel functions into locally adaptive knowledge-based neural networks: A case study on renal function evaluation Fulltext Access 10 Pages 2006
Design, synthesis, and antifungal activity of inhibitors of brassilexin detoxification in the plant pathogenic fungus Leptosphaeria maculans Fulltext Access 10 Pages 2006
Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage Fulltext Access 10 Pages 2006
Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: A catalytic cycle for the reduction of peroxynitrite Fulltext Access 10 Pages 2006
Cadmium blocks receptor-mediated Jak/STAT signaling in neurons by oxidative stress Fulltext Access 10 Pages 2006
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo Fulltext Access 10 Pages 2006
Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation Fulltext Access 10 Pages 2006
PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal Fulltext Access 10 Pages 2006
Pharmacophore-based virtual screening: The discovery of novel methionyl-tRNA synthetase inhibitors Fulltext Access 10 Pages 2006
Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents Fulltext Access 10 Pages 2006
Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells Fulltext Access 10 Pages 2006
3D-QSAR study of ring-substituted quinoline class of anti-tuberculosis agents Fulltext Access 10 Pages 2006
Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry Fulltext Access 10 Pages 2006
Cytotoxic activity of (S)-goniothalamin and analogues against human cancer cells Fulltext Access 10 Pages 2006
Molecular modeling and 3D-QSAR studies of indolomorphinan derivatives as kappa opioid antagonists Fulltext Access 10 Pages 2006
Induction of apoptosis in HeLa cells by 3β-hydroxy-12-oleanen-27-oic acid from the rhizomes of Astilbe chinensis Fulltext Access 10 Pages 2006
Combination of porphyrins and DNA-alkylation agents: Synthesis and tumor cell apoptosis induction Fulltext Access 10 Pages 2006
Synthesis and properties of 2′-O,4′-C-methyleneoxymethylene bridged nucleic acid Fulltext Access 10 Pages 2006
Enaminones 9. Further studies on the anticonvulsant activity and potential type IV phosphodiesterase inhibitory activity of substituted vinylic benzamides Fulltext Access 10 Pages 2006
Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1α,25-dihydroxyvitamin D3 analogues Fulltext Access 10 Pages 2006
Synthesis, molecular modelling and enzymatic evaluation of (±)3,5-diphenyl-2-thioxoimidazolidin-4-ones as new potential cyclooxygenase inhibitors Fulltext Access 10 Pages 2006
Dicationic pyridium porphyrins appending different peripheral substituents: Synthesis and studies for their interactions with DNA Fulltext Access 10 Pages 2006
Structure basis for the inhibitory mechanism of a novel DNase γ-specific inhibitor, DR396 Fulltext Access 10 Pages 2006